4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone

4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Structure
CAS No.
43076-30-8
Chemical Name:
4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
Synonyms
Terfenadine EP Impurity A;Terfenadine impurity A CRS;Terfenadine USP Related Compound A;4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone;1-(4-TERT-BUTYLPHENYL)-4-[4-(ALPHA-HYDROXYBENZHYDRYL)PIPERIDINO]BUTAN-1-ONE;1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one;1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one;1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-
CBNumber:
CB6884031
Molecular Formula:
C32H39NO2
Molecular Weight:
469.66
MOL File:
43076-30-8.mol
Modify Date:
2023/5/15 10:42:47

4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Properties

Melting point 175 °C
Boiling point 624.5±55.0 °C(Predicted)
Density 1.082±0.06 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly)
pka 13.32±0.29(Predicted)

4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Chemical Properties,Uses,Production

Uses

Terfenadone, is the first nonsedating antihistamine for the treatment of allergic rhinitis. It is also the derivative of Terfenadine (T114500). Terfenadine, has been also identified to be an inhibitor of human CD81-receptor HCV-E2 interaction.

4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Preparation Products And Raw materials

Raw materials

Preparation Products

4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Suppliers

Global( 7)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 China 16168 55 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56070 58 Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 China 94717 76 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone 1-(4-TERT-BUTYLPHENYL)-4-[4-(ALPHA-HYDROXYBENZHYDRYL)PIPERIDINO]BUTAN-1-ONE 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one Terfenadine impurity A CRS 1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]- Terfenadine USP Related Compound A Terfenadine EP Impurity A 43076-30-8