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cephaeline

cephaeline Structure
CAS No.
483-17-0
Chemical Name:
cephaeline
Synonyms
Cefalin;Cepheline;Aids002677;cephaeline;Alangine B;Aids-002677;Cephaelinel;(-)-Cephaelin;Desmethylemetine;Dihydropsychotrine
CBNumber:
CB6904960
Molecular Formula:
C28H38N2O4
Molecular Weight:
466.61
MOL File:
483-17-0.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:14

cephaeline Properties

Melting point 115-1160C
alpha D20 -43.4° (c = 2 in chloroform)
Boiling point 569.42°C (rough estimate)
Density 1.21±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 1.5800 (estimate)
storage temp. -20°C Freezer
solubility Acetonitrile: slightly soluble; Chloroform: slightly soluble; Ethanol: slightly soluble; Methanol: slightly soluble
form A crystalline solid
pka 9.90±0.40(Predicted)
color Light yellow to yellow
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H330-H300
Precautionary statements  P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501
RIDADR  1544
HazardClass  6.1(b)
PackingGroup  III
NFPA 704
0
4 0

cephaeline Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Uses

Has been used as an emetic and expectorant

Definition

ChEBI: A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions.

Health Hazard

The toxicity of cephaeline is lower than thatof emetine. The toxic effects are cumula tive. Ingestion of high doses may producehypotension, muscle weakness, and gastroin testinal problems, including nausea, vomiting, and diarrhea.

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United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
cephaeline O-Phosphatidyl-ethanolamine Cefalin (-)-Cephaelin (1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol 7',10,11-Trimethoxyemetan-6'-ol Cepheline Desmethylemetine Dihydropsychotrine 5853-29-2 (Dihydrochloride) Aids002677 Aids-002677 Cephaelinel Isoquinoline alkaloid Nsc32944 (dihydrochloride) Alangine B 6-Isoquinolinol, 1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-, (1R)- cephaeline USP/EP/BP NSC 32944,inhibit,Inhibitor,NSC32944,Ebola,Cephaeline,Filovirus,phenolic,alkaloid,virus,Influenza Virus,NSC-32944,Zika 483-17-0 C28H36N2O4 C28H38N2O4 C29H40N2O4 Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals