(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL

(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Structure
CAS No.
139290-65-6
Chemical Name:
(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL
Synonyms
M 100907;MDL100907;R-MDL 100907;VOLINANSERIN;MDL 100907 NEW;MDL100907-L-tartrate;MDL100907 tartrate salt;MDL 100907 (MDL-100907;MDL-100907(Volinanserin);Volinanserin (MDL100907)
CBNumber:
CB7103504
Molecular Formula:
C22H28FNO3
Molecular Weight:
373.46
MOL File:
139290-65-6.mol
MSDS File:
SDS
Modify Date:
2023/9/4 15:50:00

(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Properties

Melting point 89-91°C
Boiling point 499.4±45.0 °C(Predicted)
Density 1.150±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥20mg/mL
form powder
pka 13.93±0.20(Predicted)
color off-white to light brown

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273
Hazard Codes  N
Risk Statements  50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3

(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) M3324 M100907 ≥98% (HPLC) 139290-65-6 5MG ₹16670.5 2022-06-14 Buy
Sigma-Aldrich(India) M3324 M100907 ≥98% (HPLC) 139290-65-6 25MG ₹70135.18 2022-06-14 Buy
Product number Packaging Price Buy
M3324 5MG ₹16670.5 Buy
M3324 25MG ₹70135.18 Buy

(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Chemical Properties,Uses,Production

Description

Volinanserin is a potent and selective antagonist of the serotonin receptor 5-HT2A (Ki = 0.36-0.85 nM). It weakly binds 5-HT2C, α1-adrenergic, and sigma receptors (Ki = 88, 128, and 87 nM) and much less effectively associates with other serotonin, dopamine, adrenergic, muscarinic acetylcholine receptors and monoamine transporters. Volinanserin displays antipsychotic activity, attenuates impulsivity, and augments antidepressant effects in vivo.

Chemical Properties

Colourless solid

Uses

As a serotonin 5-HT2A receptor antagonist, Volinanserin Hydrochloride Salt can be used as potential controls in various biological studies.

General Description

M100907 blocks the serotonin 2A (5-HT2A) receptors and imposes antidepressant-like effects. It may be used for treating dopaminergic anomalies.

(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 65)Suppliers
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(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Spectrum

(+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol (aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol M 100907 R-MDL 100907 (R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol (R,R)-tartrate 4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R), (R,R)-tartrate MDL100907-L-tartrate (R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol 4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R) MDL100907 tartrate salt (+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride (aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride Volinanserin Hydrochloride Salt (+)-α-(2,3-DiMethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidineMethanol Hydrochloride (αR)-α-(2,3-DiMethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidineMethanol Hydrochloride MDL-100907(Volinanserin) (R)-(+)-a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol (R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol 4-piperidinemethanol, a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (ar)- MDL100907 4-PIPERIDINEMETHANOL, 1-[2-(4-FLUOROPHENYL)ETHYL]-ALPHA-(2,3-DIMETHOXYPHENYL)-, (ALPHAR) (R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL VOLINANSERIN (R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol MDL 100907 (MDL-100907 MDL 100907 NEW Volinanserin (MDL100907) Serotonin Receptor,inhibit,MDL 100907,5-HT Receptor,M-100907,5-hydroxytryptamine Receptor,Inhibitor,Volinanserin,M100907,MDL-100907 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (αR)- 139290-65-6 C22H29ClFNO3 C22H28FNO3C4H6O6 C22H28FNO3 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals