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(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL

(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Structure
  • ₹16670.5 - ₹70135.18
  • Product name: (R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL
  • CAS: 139290-65-6
  • MF: C22H28FNO3
  • MW: 373.46
  • EINECS:
  • MDL Number:MFCD00909060
  • Synonyms: (+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol;(aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol;M 100907;R-MDL 100907;(R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol (R,R)-tartrate;4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R), (R,R)-tartrate;MDL100907-L-tartrate;(R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol
Price2 Properties Safety Information Description
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberM3324
  • Product descriptionM100907 ≥98% (HPLC)
  • Packaging25MG
  • Price₹70135.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM3324
  • Product descriptionM100907 ≥98% (HPLC)
  • Packaging5MG
  • Price₹16670.5
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M3324 M100907 ≥98% (HPLC) 25MG ₹70135.18 2022-06-14 Buy
Sigma-Aldrich(India) M3324 M100907 ≥98% (HPLC) 5MG ₹16670.5 2022-06-14 Buy

Properties

Melting point :89-91°C
Boiling point :499.4±45.0 °C(Predicted)
Density :1.150±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
form :powder
pka :13.93±0.20(Predicted)
color :off-white to light brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

Volinanserin is a potent and selective antagonist of the serotonin receptor 5-HT2A (Ki = 0.36-0.85 nM). It weakly binds 5-HT2C, α1-adrenergic, and sigma receptors (Ki = 88, 128, and 87 nM) and much less effectively associates with other serotonin, dopamine, adrenergic, muscarinic acetylcholine receptors and monoamine transporters. Volinanserin displays antipsychotic activity, attenuates impulsivity, and augments antidepressant effects in vivo.

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