mexidol
- CAS No.
- 127464-43-1
- Chemical Name:
- mexidol
- Synonyms
- Emoxypine Succinate;ETHYLMETHYLHYDROXYPYRIDINE SUCCINATE;Mexifin;2-Ethyl-6-methyl-3-hydroxypyridine succinate;Mexidole;Emoxypine Succinate (Mexidol);mexidol;Mexiletine base;Mexidol succinate;Methoxyl west dol
- CBNumber:
- CB71331340
- Molecular Formula:
- C8H11NO.C4H6O4
- Molecular Weight:
- 255.268
- MOL File:
- 127464-43-1.mol
- Modify Date:
- 2024/5/18 8:51:54
| Melting point | 119-120 °C |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C8H11NO.C4H6O4/c1-3-7-8(10)5-4-6(2)9-7;5-3(6)1-2-4(7)8/h4-5,10H,3H2,1-2H3;1-2H2,(H,5,6)(H,7,8) |
| InChIKey | IKMNOGHPKNFPTK-UHFFFAOYSA-N |
| SMILES | C1(CC)N=C(C=CC=1O)C.C(C(=O)O)CC(=O)O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HS Code | 2933.39.9200 |
mexidol Chemical Properties,Uses,Production
Uses
The Chinese name of Mesidol is 2-ethyl-6methyl-3-hydroxypyridine succinic acid (Mexidox), 2-ethyl-6-methyl-3-hydroxypyridine succinate (emoxypine, product Name-MEXIDOL?, etc.) is widely used in medicine as an antioxidant and anti-hypoxic agent. Use 2-ethyl-6-methyl-3-hydroxypyridine succinate as a nootropic and anxiolytic, anti-ischemic and atherosclerotic, anti-angina, liver protection, antibacterial, etc.
Preparation
3.5 liters of ethanol, 1.2 kg of 2-ethyl-6-methyl-3-hydroxypyridine and 1.0 kg of succinic acid were added to the reactor. The reaction mass is heated to the boiling point of ethanol (78°C) and stirring is continued for 20 minutes until the components are completely dissolved. Then, keep the reaction mass in the reactor under stirring until the temperature reaches 20°C, cool to 5°C and keep at this temperature for 16 hours, stirring occasionally. The suspension is then stirred until the material is homogeneous, overloaded in a centrifuge and filtered. The precipitate of the succinate salt of 2-ethyl-6-methyl-3-hydroxypyridine was dried to constant weight in a vacuum oven at 45°C. The yield of the target product 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexitrad) was 89%.
mexidol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SOLFYN INTERNATIONAL LLP | +91-9321772608 +91-9321772608 | Mumbai, India | 105 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Neel Kanth Drugs Private Limited | 08069033721Ext 594 | Delhi, India | 6 | 58 | Inquiry |
| Prasol Chemicals Private Limited | 08046048267 | Mumbai, India | 49 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD | +8618291886785 | China | 164 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5872 | 58 | Inquiry |
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