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Inosine

CAS No.: 58-63-9

Chemical Name:: Inosine

Synonyms: RIBOXINE;(-)-INOSINE;(-)-Inosine;HXR;nosine;(2R,3R,4S,5R)-2-(6-hydroxy-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol;Ino;Atorel;Inosie;Selfer

CBNumber:: CB7161412

Molecular Formula:: C10H12N4O5

Molecular Weight:: 268.23

MOL File:: 58-63-9.mol

MSDS File:: SDS

Modify Date:: 2024/5/31 17:33:32

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Inosine Properties

Melting point	222-226 °C (dec.) (lit.)
alpha	-49.2 º (c=1,H2O 18 ºC)
Boiling point	226 C (dec.)
Density	1.3846 (rough estimate)
refractive index	-52 ° (C=1, H2O)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	H₂O: 0.5 M, clear, colorless
pka	13.24±0.70(Predicted)
form	Crystalline Powder
color	White
Odor	Odorless
Water Solubility	2.1 g/100 mL (20 ºC)
Merck	14,4975
BRN	624889
Stability	Hygroscopic
InChIKey	UGQMRVRMYYASKQ-PKJMTWSGSA-N
LogP	-1.970 (est)
CAS DataBase Reference	58-63-9(CAS DataBase Reference)
NIST Chemistry Reference	Inosine(58-63-9)
EPA Substance Registry System	Inosine (58-63-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

24/25-36-26

WGK Germany

RTECS

NM7460000

TSCA

Yes

HS Code

29389090

Toxicity

LD50 oral in rat: > 10gm/kg

NFPA 704

	1
0		0

Inosine price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	I4125	Inosine ≥99% (HPLC)	58-63-9	5G	₹2013.45	2022-06-14	Buy
Sigma-Aldrich(India)	I4125	Inosine ≥99% (HPLC)	58-63-9	1G	₹2359.85	2022-06-14	Buy
Sigma-Aldrich(India)	I4125	Inosine ≥99% (HPLC)	58-63-9	10G	₹3247.5	2022-06-14	Buy
Sigma-Aldrich(India)	I4125	Inosine ≥99% (HPLC)	58-63-9	25G	₹5163.53	2022-06-14	Buy
Sigma-Aldrich(India)	PHR2412	Adenosine Impurity G Pharmaceutical Secondary Standard; Certified Reference Material	58-63-9	100MG	₹31868.8	2022-06-14	Buy

Product number	Packaging	Price	Buy
I4125	5G	₹2013.45	Buy
I4125	1G	₹2359.85	Buy
I4125	10G	₹3247.5	Buy
I4125	25G	₹5163.53	Buy
PHR2412	100MG	₹31868.8	Buy

Inosine Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Occurrence

Inosine is a synthetic

Uses

Inosine has been used:

as a medium supplement in nucleotide rescue experiments in pancreatic cancer cell lines.
as a component in holidic (synthetic) medium and in larval two-choice preference assay.
as a reference standard in mass spectroscopy.

Definition

ChEBI: A purine nucleoside in which hypoxanthine is attached to ribofuranose via a beta-N9-glycosidic bond.

General Description

Inosine is a non-canonical nucleotide majorly present as monophosphate. It has ability to base pair with deoxythymidine, deoxyadenosine and deoxyguanosine. Incorporation of inosine in place of guanine modulates translational events. Inosine has antioxidant, anti-inflammatory and neuroprotective functionality. Inosine is prescribed as a therapeutic supplement for nerve injury, inflammation and oxidative stress. It modulates biological processes through adenosine receptors. Its enhances neurite outgrowth in depressive disorders via adenosine receptors. Inosine is also used for treating sepsis in infections.

Purification Methods

(-)-Inosine forms anhydrous crystals from aqueous 80% EtOH but the dihydrate from H2O. [Beilstein 31 H 25, 26 III/IV 2087.]

Inosine Preparation Products And Raw materials

Raw materials

Acid off Platinum Disodium 5'-Inosinate Sodium chloride Guanosine 5'-monophosphate disodium salt

Agar TRIS BORATE EDTA BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY BEEF EXTRACT Inosinic Acid Yeast extract

corn syrup Sulfuric acid Adenosine BARIUM NITRITE

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Preparation Products

Dideoxyinosine Ribavirin beta-D-Ribofuranose 1,2,3,5-tetraacetate DL-Tryptophan Calcium 5'-ribonucleotide

2-(6-ethylaminopurin-9-yl)-5-(hydroxymethyl)oxol 5''-O-(4,4''-Dimethoxytrityl)-inosine 6-Chloropurine ribonucleoside N6-CYCLOHEXYLADENOSINE

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Inosine Suppliers

Global( 721)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEANCHEM LABORATORIES LLP	+91-9951015911 +91-9951015911	Mumbai, India	281	58	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
S D Fine Chem Limited	+91-9323715856 +91-9323715856	Maharashtra, India	368	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
ALPHA CHEMIKA	+91-22-22061123 +91-22-66382501	Mumbai, India	1681	43	Inquiry
Loba Chemie Pvt., Ltd.	91-22-66636663	Maharashtra, India	766	58	Inquiry
Scientific OEM	+91-22- 2343 7546 / 2341 3094	New Delhi, India	1996	38	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry

Supplier	Advantage
CLEANCHEM LABORATORIES LLP	58
JSK Chemicals	58
S D Fine Chem Limited	58
TCI Chemicals (India) Pvt. Ltd.	58
ALPHA CHEMIKA	43
Loba Chemie Pvt., Ltd.	58
Scientific OEM	38
CHEMSWORTH	30
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58

Inosine Spectrum

Inosine(58-63-9)MS Inosine(58-63-9)¹HNMR Inosine(58-63-9)¹³CNMR Inosine(58-63-9)IR1 Inosine(58-63-9)IR2 Inosine(58-63-9)Raman

58-63-9(Inosine)Related Search:

6-Hydroxypurine Inosine Impurity 1 AICAR L-Inosine 2-CHLOROINOSINE

1-METHYLGUANOSINE 2',3',5'-TRI-O-ACETYLINOSINE GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Disodium 5'-Inosinate Isoprinosine

Inosine, 2',3'-dideoxy- Zalcitabine 2'-Deoxyinosine 5'-monophosphate disodium salt 2'-Deoxy-D-inosine Dinaphtho[2,3-a:2',3'-i]naphth[2',3':6,7]indolo[2,3-c]carbazole-5,10,15,17,22,24-hexol hexakis(hydrogen salfate)

Inosine-5-triphosphate trisodium Guanosine 5'-monophosphate disodium salt 2',3'-O-Isopropylideneinosine

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Atorel beta-D-Ribofuranoside, hypoxanthine-9 beta-Inosine Hypoxanthine D-riboside Hypoxanthine, 9-beta-D-ribofuranosyl- hypoxanthined-riboside hypoxanthinenucleoside Ino INO 495 Inosie Oxiamin Panholic-L Pantholic-L Ribonosine Selfer Trophicardyl INOSINE HYPOXANTHINE-9-BETA-D-RIBOFURANOSIDE HYPOXANTHINE 9-D-RIBOFURANOSIDE HYPOXANTHINE RIBONUCLEOSIDE HYPOXANTHINE RIBOSIDE HYPOXANTHOSINE 9-BETA-RIBOFURANOSYLHYPOXANTHINE 9-BETA-D-RIBOFURANOSYLHYPOXANTHINE 9-B-D-RIBOFURANOSYLHYPOXANTHINE 9-[3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-3H-PURIN-6-ONE 9-((2R,3R,4S,5R)-3,4-DIHYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1,9-DIHYDRO-PURIN-6-ONE 6-HYDROXYPURINE RIBOSIDE Inosine AJI92 INOSINE SIGMAULTRA INOSINE, CRYSTALLIZED Inosine,FreeBase InosineForBiochemistry99% Inosine,>98% hypoxanthine-9-á-d-ribofuranoside B-INOSINE D-Inosine [1',2',3',4',5'-13C5]inosine Inosine, 97+% 12712-98-0 132953-54-9 28861-88-3 4181-51-5 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]-3H-purin-6-one 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-3H-purin-6-one C00294 InChI=1/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,1 SMR000058316 ZINC05127790 9-[(2S,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one INOSINE,REAGENT 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one 1,9-Dihydro-9-β-D-ribofuranosyl-6H-purin-6-one 6H-Purin-6-one, 1,9-dihydro-9-β-D-ribofuranosyl- 9-β-D-Ribofuranosylhypoxanthine Hypoxanthine, 9-β-D-ribofuranosyl- Inosine (8CI, 9CI)