Inosine
![Inosine Structure](CAS/GIF/58-63-9.gif)
- CAS No.
- 58-63-9
- Chemical Name:
- Inosine
- Synonyms
- RIBOXINE;(-)-INOSINE;(-)-Inosine;HXR;nosine;(2R,3R,4S,5R)-2-(6-hydroxy-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol;Ino;Atorel;Inosie;Selfer
- CBNumber:
- CB7161412
- Molecular Formula:
- C10H12N4O5
- Molecular Weight:
- 268.23
- MOL File:
- 58-63-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/31 17:33:32
Melting point | 222-226 °C (dec.) (lit.) |
---|---|
alpha | -49.2 º (c=1,H2O 18 ºC) |
Boiling point | 226 C (dec.) |
Density | 1.3846 (rough estimate) |
refractive index | -52 ° (C=1, H2O) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | H2O: 0.5 M, clear, colorless |
pka | 13.24±0.70(Predicted) |
form | Crystalline Powder |
color | White |
Odor | Odorless |
Water Solubility | 2.1 g/100 mL (20 ºC) |
Merck | 14,4975 |
BRN | 624889 |
Stability | Hygroscopic |
InChIKey | UGQMRVRMYYASKQ-PKJMTWSGSA-N |
LogP | -1.970 (est) |
CAS DataBase Reference | 58-63-9(CAS DataBase Reference) |
NIST Chemistry Reference | Inosine(58-63-9) |
EPA Substance Registry System | Inosine (58-63-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 24/25-36-26 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | NM7460000 | |||||||||
F | 10 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29389090 | |||||||||
Toxicity | LD50 oral in rat: > 10gm/kg | |||||||||
NFPA 704 |
|
Inosine price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | I4125 | Inosine ≥99% (HPLC) | 58-63-9 | 5G | ₹2013.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | I4125 | Inosine ≥99% (HPLC) | 58-63-9 | 1G | ₹2359.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | I4125 | Inosine ≥99% (HPLC) | 58-63-9 | 10G | ₹3247.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | I4125 | Inosine ≥99% (HPLC) | 58-63-9 | 25G | ₹5163.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR2412 | Adenosine Impurity G Pharmaceutical Secondary Standard; Certified Reference Material | 58-63-9 | 100MG | ₹31868.8 | 2022-06-14 | Buy |
Inosine Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Occurrence
Inosine is a synthetic
Uses
Inosine has been used:
- as a medium supplement in nucleotide rescue experiments in pancreatic cancer cell lines.
- as a component in holidic (synthetic) medium and in larval two-choice preference assay.
- as a reference standard in mass spectroscopy.
Definition
ChEBI: A purine nucleoside in which hypoxanthine is attached to ribofuranose via a beta-N9-glycosidic bond.
General Description
Inosine is a non-canonical nucleotide majorly present as monophosphate. It has ability to base pair with deoxythymidine, deoxyadenosine and deoxyguanosine. Incorporation of inosine in place of guanine modulates translational events. Inosine has antioxidant, anti-inflammatory and neuroprotective functionality. Inosine is prescribed as a therapeutic supplement for nerve injury, inflammation and oxidative stress. It modulates biological processes through adenosine receptors. Its enhances neurite outgrowth in depressive disorders via adenosine receptors. Inosine is also used for treating sepsis in infections.
Purification Methods
(-)-Inosine forms anhydrous crystals from aqueous 80% EtOH but the dihydrate from H2O. [Beilstein 31 H 25, 26 III/IV 2087.]
Inosine Preparation Products And Raw materials
Raw materials
1of3
chevron_rightPreparation Products
1of2
chevron_rightSupplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEANCHEM LABORATORIES LLP | +91-9951015911 +91-9951015911 | Mumbai, India | 281 | 58 | Inquiry |
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
S D Fine Chem Limited | +91-9323715856 +91-9323715856 | Maharashtra, India | 368 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
Loba Chemie Pvt., Ltd. | 91-22-66636663 | Maharashtra, India | 766 | 58 | Inquiry |
Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Supplier | Advantage |
---|---|
CLEANCHEM LABORATORIES LLP | 58 |
JSK Chemicals | 58 |
S D Fine Chem Limited | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
ALPHA CHEMIKA | 43 |
Loba Chemie Pvt., Ltd. | 58 |
Scientific OEM | 38 |
CHEMSWORTH | 30 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
58-63-9(Inosine)Related Search:
1of4
chevron_right