ChemicalBook > Product Catalog >Organic Chemistry >Alcohols,Phenols,Phenol alcohols >Phenol derivatives >4-Bromophenol

4-Bromophenol

4-Bromophenol Structure
CAS No.
106-41-2
Chemical Name:
4-Bromophenol
Synonyms
P-BROMOPHENOL;Para Bromo Phenol;4-Bromphenol;Phenol, 4-bromo-;NSC 4970;p-Bromphenol;4-BROMOPHENOL;BROMOPHENOL-4;P-Bromophenlo;4-bromo-pheno
CBNumber:
CB7181317
Molecular Formula:
C6H5BrO
Molecular Weight:
173.01
MOL File:
106-41-2.mol
MSDS File:
SDS
Modify Date:
2023/7/4 17:14:15

4-Bromophenol Properties

Melting point 61-64 °C (lit.)
Boiling point 235-236 °C (lit.)
Density 1.84
refractive index 1.5085 (estimate)
Flash point 235-238°C
storage temp. room temp
solubility 14g/l
form Crystalline Solid
pka 9.37(at 25℃)
color Pinkish-brown
Water Solubility It is insoluble in water. It is soluble in 5%ethanol.
λmax 282nm(EtOH)(lit.)
Merck 14,1428
BRN 1680024
CAS DataBase Reference 106-41-2(CAS DataBase Reference)
NIST Chemistry Reference 4-Bromophenol(106-41-2)
EPA Substance Registry System Phenol, 4-bromo- (106-41-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315
Precautionary statements  P264-P270-P280-P301+P312-P302+P352-P332+P313
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-37/39-36
RIDADR  2811
WGK Germany  2
RTECS  SJ7960000
8-10-23
Hazard Note  Irritant
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29081000
Toxicity mouse,LD50,intraperitoneal,411mg/kg (411mg/kg),Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 44(12), Pg. 19, 1979.
NFPA 704
0
2 0

4-Bromophenol price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) B75808 4-Bromophenol 99% 106-41-2 5G ₹1980 2022-06-14 Buy
Sigma-Aldrich(India) B75808 4-Bromophenol 99% 106-41-2 100G ₹3450 2022-06-14 Buy
Sigma-Aldrich(India) B75808 4-Bromophenol 99% 106-41-2 500G ₹11770 2022-06-14 Buy
TCI Chemicals (India) B3910 4-Bromophenol [for Biochemical Research] min. 98.0 % 106-41-2 1G ₹2700 2022-05-26 Buy
ALFA India ALF-A14873-36 4-Bromophenol, 99% 106-41-2 500g ₹8309 2022-05-26 Buy
Product number Packaging Price Buy
B75808 5G ₹1980 Buy
B75808 100G ₹3450 Buy
B75808 500G ₹11770 Buy
B3910 1G ₹2700 Buy
ALF-A14873-36 500g ₹8309 Buy

4-Bromophenol Chemical Properties,Uses,Production

Chemical Properties

4-Bromophenol is a pinkish-brown crystalline solid. four-sided biconical crystal precipitated from ether or chloroform. The melting point is 66.4 ℃, and a small amount of water can reduce the melting point a lot. Soluble in water, chloroform, easily soluble in ethanol, ether and glacial acetic acid, soluble in 7 parts of water.

Application

4-Bromophenol is a phenolic derivative that It can used as a reagent in Stille reactions or Intermediates of Liquid Crystals.

Preparation

4-Bromophenol is synthesized by bromination of phenol. The bromine and carbon disulfide solution was added to the phenolic carbon disulfide solution, and the addition was started below 5°C, and the addition was completed under stirring for 2 hours. Phenol and bromine are approximately equimolar ingredients. Distill the reactant to remove carbon disulfide, and then conduct fractional distillation under reduced pressure to collect fractions at 145-150°C (3.32-3.99kPa) to obtain the product. Yield 80-84%.

Purification Methods

Crystallise the phenol from CHCl3, CCl4, pet ether (b 40-60o), or water and dry it at 70o under vacuum for 2hours. [Beilstein 6 IV 1043.]

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