UNOPROSTONE

UNOPROSTONE Structure
CAS No.
120373-36-6
Chemical Name:
UNOPROSTONE
Synonyms
UNOPROSTONE;Unii-6X4F561V3w;Unoprostone [inn];Emorfazone Impurity 6;Alprostadil Impurity 20;13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA;9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID;(E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-
CBNumber:
CB7220472
Molecular Formula:
C22H38O5
Molecular Weight:
382.53
MOL File:
120373-36-6.mol
Modify Date:
2023/6/8 9:02:17

UNOPROSTONE Properties

Boiling point 562.9±40.0 °C(Predicted)
Density 1.069±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMSO: 17 mg/ml; Ethanol: 12 mg/ml; PBS (7.2): 90 μg/ml
pka 4.76±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360
NFPA 704
3
2 0

UNOPROSTONE Chemical Properties,Uses,Production

Uses

Unoprostane is a protectant against retinal degeneration in S334ter rhodopsin mutant rats. Neuroprotective agent.

General Description

Unoprostone (Rescula) is supplied as a 0.15% sterileophthalmic solution. Unoprostone is somewhat unusual inthat it is a docosanoid (22-carbon atom) PGF analog marketedas the isopropyl ester. The natural 15-position alcoholis oxidized to the ketone as would be expected to occur invivo. Cautions and side effects are similar to those givenpreviously.

UNOPROSTONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 42)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
PT CHEM GROUP LIMITED +86-85511178 +86-85511178 China 35451 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Xiamen Eagle Chemical Limited Corporation +86-5925023701 +86-18900207489 China 6046 58 Inquiry
UNOPROSTONE 9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID Unii-6X4F561V3w Unoprostone [inn] 13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)- Alprostadil Impurity 20 Emorfazone Impurity 6 120373-36-6