1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE

CAS No.: 353791-85-2

Chemical Name:: 1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE

Synonyms: J 113863;1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE;CCR,Inhibitor,inhibit,rheumatoid,J-113863,CCR1,CCR3,CC chemokine receptor,Chemotaxis,collagen,arthritis,J 113863,J113863,CD18,anti-inflammatory

CBNumber:: CB72453425

Molecular Formula:: C30H37Cl2IN2O2

Molecular Weight:: 655.44

MOL File:: 353791-85-2.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:16

Request For Quotation

1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Properties

storage temp.	Store at +4°C
solubility	Soluble to 100 mM in DMSO and to 50 mM in ethanol
form	Powder
color	Light yellow to yellow

1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Chemical Properties,Uses,Production

Uses

UCB 35625 is an antagonist of CCR1, which are receptors prevalent in chronic inflammatory processes. UCB 35625 displays antiarthritic activity and is also a selective antagonist of CCR3.

Biological Activity

Potent chemokine receptor 1 (CCR1) antagonist (IC 50 values are 0.9 and 5.8 nM for human and mouse CCR1 receptors respectively). Also displays high selectivity for human but not mouse CCR3 receptors (IC 50 values are 0.58 and 460 nM respectively). Improves paw inflammation, joint damage and dramatically reduces cell infiltration into joints in collagen-induced arthritis in mice. Isomer of UCB 35625 (1,4-trans-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidiniumiodide ).

1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Suppliers

Global( 26)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
InvivoChem	13549236410	China	6747	58	Inquiry
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	China	3770	55	Inquiry
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	China	9707	58	Inquiry
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 18112977050	China	10529	58	Inquiry
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	China	11289	58	Inquiry
United States Biological	800.520.3011 or 781.639.5092	United States	6256	80	Inquiry
Kaifeng Mingren Pharmaceutical Co.,LTD	0371-65741762	China	2380	58	Inquiry
Shanghai Universal Biotech Co.,Ltd	18768175414	China	24998	58	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
InvivoChem	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Shanghai EFE Biological Technology Co., Ltd.	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
United States Biological	80
Kaifeng Mingren Pharmaceutical Co.,LTD	58
Shanghai Universal Biotech Co.,Ltd	58

353791-85-2(1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE)Related Search:

1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE TRIMETHYLNONYLAMMONIUMIODIDE XANTHENE-9-CARBOXAMIDE XANTHENE-9-METHYLAMINE ALLYLTRIETHYLAMMONIUM IODIDE

1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE J 113863 CCR,Inhibitor,inhibit,rheumatoid,J-113863,CCR1,CCR3,CC chemokine receptor,Chemotaxis,collagen,arthritis,J 113863,J113863,CD18,anti-inflammatory 353791-85-2