1-O-HEXADECYL-SN-GLYCEROL
- CAS No.
- 506-03-6
- Chemical Name:
- 1-O-HEXADECYL-SN-GLYCEROL
- Synonyms
- CHIMYL ALCOHOL;1-C16 Ether MG;1-hexadecylglycerol;1-o-hexadecylglycerol;MONOCERYL GLYCERYL ETHER;α-hexadecylglyceryl ether;1-O-HEXADECYL-SN-GLYCEROL;1-O-PALMITOYL-SN-GLYCEROL;3-cetyloxypropane-1,2-diol;3-hexadecoxypropane-1,2-diol
- CBNumber:
- CB7247866
- Molecular Formula:
- C19H40O3
- Molecular Weight:
- 316.52
- MOL File:
- 506-03-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/12/21 14:55:28
| Melting point | 64° |
|---|---|
| alpha | D20 +3.0° (c = 1.16 in chloroform) |
| Boiling point | bp0.005 120° |
| Density | 1.0054 (rough estimate) |
| refractive index | 1.4410 (estimate) |
| storage temp. | -15°C |
| solubility | DMF: 16 mg/ml; DMSO: 0.16 mg/ml; Ethanol: 5 mg/ml |
| form | A crystalline solid |
| pka | 13.68±0.20(Predicted) |
| LogP | 6.702 (est) |
1-O-HEXADECYL-SN-GLYCEROL Chemical Properties,Uses,Production
Description
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; ) in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.
Uses
1-O-Hexadecyl-sn-glycerol restores plasmalogen levels in Chinese hamster ovary (CHO) cells and human pulmonary arterial endothelial cells (PAEC). Plasmalogen may play a role in protecting animal cells against photosensitized killing.
Definition
ChEBI: A 1-n-hexadecyl analogue of an optically active alkylglycerol compound.
Purification Methods
Recrystallise it from hexane. [Beilstein 1 III 2322.]
1-O-HEXADECYL-SN-GLYCEROL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16220 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | China | 2417 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
| Alfa Chemistry | +1-5166625404 | United States | 21317 | 58 | Inquiry |
| Meike meditech (Foshan) Co.,Ltd | +86-0757-22239986 +86-18029359586 | China | 1134 | 58 | Inquiry |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | China | 2989 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
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