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Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde

Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Structure
CAS No.
124750-67-0
Chemical Name:
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
Synonyms
Losartan Related compund A;Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde;2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile;2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde;[1,1'-Biphenyl]-2-carbonitrile, 4'-[(2-butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-;Losartan Related Compound A 4’-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-[1,1’- Biphenyl]-2-carbonitrile
CBNumber:
CB72709030
Molecular Formula:
C22H20ClN3O
Molecular Weight:
377.87
MOL File:
124750-67-0.mol
MSDS File:
SDS
Modify Date:
2023/7/11 8:28:12
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Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Properties

Melting point 99 °C(Solv: methanol (67-56-1))
Boiling point 590.1±50.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
pka 1.54±0.60(Predicted)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H317-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501

Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Chemical Properties,Uses,Production

Uses

Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is a derivative of Losartan carboxaldehyde (L470505). Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is also used as reagent to synthesize Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.

Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Losartan potassium

Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Suppliers

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Supplier Advantage
SynThink RESEARCH CHEMICALS 58
GLP Pharma Standards 58
KARPSCHEM LABORATORIES 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Labnetwork lnc. 58
sgtlifesciences pvt ltd 58
Wuhan Yuxiang Medical Technology Co., Ltd. 58
Shanghai YuZn Pharm. Technology Co.,Ltd. 58
BOC Sciences 65
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde 2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile [1,1'-Biphenyl]-2-carbonitrile, 4'-[(2-butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]- 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde Losartan Related compund A Losartan Related Compound A 4’-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-[1,1’- Biphenyl]-2-carbonitrile 124750-67-0