4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile

CAS No.: 114772-55-3

Chemical Name:: 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile

Synonyms: Losartan Impurity 8;1'-Biphenyl]-2-carbonitrile;Benzene,1,3,5-tribromo-2,4,10-trimethyl-;4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-;Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan;4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1;4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)- biphenyl-2-carbonitrile;2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile;4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile;2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl)imidazolyl]methyl} phenyl)benzene carbonitrile

CBNumber:: CB82103743

Molecular Formula:: C22H22ClN3O

Molecular Weight:: 379.88

MOL File:: 114772-55-3.mol

MSDS File:: SDS

Modify Date:: 2023/4/23 13:52:06

Request For Quotation

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Properties

Melting point	157-158°C
Boiling point	605.6±55.0 °C(Predicted)
Density	1.19
storage temp.	Refrigerator
solubility	DMSO (Slightly), Ethyl Acetate (Slightly)
pka	13.66±0.10(Predicted)
form	Solid
color	White to Off-White

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Chemical Properties,Uses,Production

Uses

Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan is a derivative of Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Preparation Products And Raw materials

Raw materials

Methyl Pentanimidate 4'-Methyl-2-cyanobiphenyl (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL 3-(4-BROMOBENZYL)-2-BUTYL-4-CHLORO-1H-IMIDAZOL-5-YLMETHANOL Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde

2-(2-METHOXYPHENYL)-4,4-DIMETHYL-2-OXAZOLINE N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE 2-Butyl-4-chloro-5-formylimidazole 4,4-DIMETHYL-2-(4'-METHYL-2-BIPHENYLYL)-2-OXAZOLINE Valeronitrile

o-Anisoyl chloride o-Anisic acid 4-Bromomethyl-2-cyanobiphenyl

chevron_left

1of3

chevron_right

Preparation Products

Losartan potassium

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Suppliers

Global( 85)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SynThink RESEARCH CHEMICALS	+91-8177860948 +91-8177860948	Mumbai, India	494	58	Inquiry
GLP Pharma Standards	+91 9866074638	Hyderabad, India	1644	58	Inquiry
KARPSCHEM LABORATORIES	+91-7249203006 +91-7249203006	Maharashtra, India	786	58	Inquiry
Viyash Life Sciences Pvt Ltd	+91-4023635052 +91-4023635052	Telangana, India	213	58	Inquiry
Saburi Life Sciences	+91-9052929666 +91-9177339666	Hyderabad, India	91	58	Inquiry
Raising Sun Pharma	+91-9399941155 +91-9399941155	Telangana, India	127	58	Inquiry
Ralington Pharma	+91-7948911722 +91-9687771722	Gujarat, India	1350	58	Inquiry
SL Drugs and Pharmaceuticals Pvt. Ltd.	+91 (40) 6661-1133	New Delhi, India	2688	50	Inquiry
Clinse Labs Private Limited.	+091-40-23778611	New Delhi, India	372	30	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry

Supplier	Advantage
SynThink RESEARCH CHEMICALS	58
GLP Pharma Standards	58
KARPSCHEM LABORATORIES	58
Viyash Life Sciences Pvt Ltd	58
Saburi Life Sciences	58
Raising Sun Pharma	58
Ralington Pharma	58
SL Drugs and Pharmaceuticals Pvt. Ltd.	50
Clinse Labs Private Limited.	30
CLEARSYNTH LABS LTD.	58

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile 4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)- biphenyl-2-carbonitrile Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan 2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile 4'-[(2-BUTYL-4-CHLORO-5-HYDROXYMETHYL-1H-IMIDAZOL-1-YL)METHYL]-1,1'-BIPHENYL-2-CARBONITRILE 114772-55-3 [1,1'-Biphenyl]-2-carbonitrile, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]- 4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile 4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1 1'-Biphenyl]-2-carbonitrile Losartan Impurity 8 2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl)imidazolyl]methyl} phenyl)benzene carbonitrile Benzene,1,3,5-tribromo-2,4,10-trimethyl- Losartan Related Compound B 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1- yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H- 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile 114772-55-3 Losartan Potassium