Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >API >Circulatory system drugs >Antihypertensive drugs >2-Butyl-4-chloro-5-formylimidazole

2-Butyl-4-chloro-5-formylimidazole

2-Butyl-4-chloro-5-formylimidazole Structure
CAS No.
83857-96-9
Chemical Name:
2-Butyl-4-chloro-5-formylimidazole
Synonyms
BCFI;2-BUTYL-4-CHLORO-1H-IMIDAZOLE-5-CARBALDEHYDE;2-BUTYL-5-CHLORO-1H-IMIDAZOLE-4-CARBALDEHYDE;2-Butyl-4-chloroimidazole-5-carboxaldehyde;Losaint-A;ALSTint-A03;Losartan potassium-1;LOSARTAN INTERMEDIATES;Losartan EP IMpurity D;Losartan impurity D CRS
CBNumber:
CB4185349
Molecular Formula:
C8H11ClN2O
Molecular Weight:
186.64
MOL File:
83857-96-9.mol
MSDS File:
SDS
Modify Date:
2025/2/26 21:25:56
Request For Quotation

2-Butyl-4-chloro-5-formylimidazole Properties

Melting point 97-100 °C(lit.)
Boiling point 384.1±22.0 °C(Predicted)
Density 1.240
vapor pressure 0.001Pa at 25℃
storage temp. Inert atmosphere,2-8°C
solubility soluble in methanol
form Powder to crystal
pka 8.87±0.10(Predicted)
color Pale Yellow to Brown
Water Solubility slightly soluble
InChIKey JLVIHQCWASNXCK-UHFFFAOYSA-N
LogP 2.5 at 25℃ and pH7.1
Surface tension 58.3mN/m at 1.2g/L and 20℃
CAS DataBase Reference 83857-96-9(CAS DataBase Reference)
EPA Substance Registry System 2-Butyl-5-chloroimidazole-4-carbaldehyde (83857-96-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H317-H411
Precautionary statements  P261-P272-P273-P280-P302+P352-P333+P313
Hazard Codes  Xi,N
Risk Statements  43-51/53
Safety Statements  24-37-61
RIDADR  UN 3077 9/PG 3
WGK Germany  2
HazardClass  IRRITANT
PackingGroup  III
HS Code  29339900
NFPA 704
0
2 0

2-Butyl-4-chloro-5-formylimidazole price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 559881 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde 97% 83857-96-9 25G ₹13379.7 2022-06-14 Buy
TCI Chemicals (India) B2914 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde min. 98.0 % 83857-96-9 25G ₹9800 2022-05-26 Buy
Product number Packaging Price Buy
559881 25G ₹13379.7 Buy
B2914 25G ₹9800 Buy

2-Butyl-4-chloro-5-formylimidazole Chemical Properties,Uses,Production

Description

2-Butyl-4-chloro-5-formylimidazole is an API intermediate used as an intermediate for the anti-hypertensive drug Chlosartan. It can be used in the chemical manufacture of many APIs and advanced intermediates. With the help of this chemical, a number of other chemicals can be manufactured that have further applications in industries such as Losartan manufacturing.

Chemical Properties

2-Butyl-4-chloro-5-formylimidazole is Yellow Solid

Uses

2-Butyl-4-chloro-5-formylimidazole is used for preparation of N-(biphenylylmethyl)imidazoles as angiotensin II antagonists

Application

2-Butyl-4-chloro-1H-imidazole-5-carboxaldehyde (Losartan EP Impurity D) is used for preparation of N-(biphenylylmethyl)imidazoles as angiotensin II antagonists. Losartan USP Related Compound A.

Synthesis

2-Butyl-4-chloro-5-formylimidazole was synthesised as follows: Performing condensation reaction of pentamidine hydrochloride with glyoxal and controlling the pH value of the system in the range of 6.0-7.5; after the reaction terminates, arousing dehydration reaction of the compound of formula III, thereby obtaining 2-butyl-1H-imidazole-5(4H)-ketone; and finally, reacting 2-butyl-1H-imidazole-5(4H)-ketone with N,N-dimethylformamide in the presence of phosphorus oxychloride, thereby obtaining 2-butyl-4-chloro-5-formylimidazole.

storage

2-Butyl-4-chloro-5-formylimidazole is soluble in DMF, DMSO, Ethanol and Methanol.

2-Butyl-4-chloro-5-formylimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL EPROSARTAN N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde

2-Butyl-4-chloro-5-formylimidazole Suppliers

Global( 573)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
GLR Innovations +91 9891111994 New Delhi, India 4535 58 Inquiry
Vijayasri Organics Private Limited +91-9848990113 +91-9848990113 Telangana, India 43 58 Inquiry
VASISTA LIFE SCIENCES PRIVATE LIMITED +91-04029554774 +91-9010855544 Hyderabad, India 153 58 Inquiry
Biosyn Research Chemicals +91-91-9346022300 +91-9346022300 Telangana, India 465 58 Inquiry
Indo Amines Ltd +91-7045592702 +91-7045592702 Mumbai, India 42 58 Inquiry
GSV speciality chemicals +91-91823634932 +91-91823634932 Hyderabad, India 135 58 Inquiry
SNECOFRi Pvt Ltd +91-9032850129 +91-9032850129 Telangana, India 403 58 Inquiry
KARPSCHEM LABORATORIES +91-7249203006 +91-7249203006 Maharashtra, India 786 58 Inquiry
Rutu Chemicals +91-9904014859 +91-9904014859 Gujarat, India 10 58 Inquiry
Sam Fine O Chem Limited +91-9987622299 +91-9987622299 Maharashtra, India 93 58 Inquiry
Supplier Advantage
GLR Innovations 58
Vijayasri Organics Private Limited 58
VASISTA LIFE SCIENCES PRIVATE LIMITED 58
Biosyn Research Chemicals 58
Indo Amines Ltd 58
GSV speciality chemicals 58
SNECOFRi Pvt Ltd 58
KARPSCHEM LABORATORIES 58
Rutu Chemicals 58
Sam Fine O Chem Limited 58

2-Butyl-4-chloro-5-formylimidazole Spectrum

2-Butyl-4-chloro-5-formylimidazole(83857-96-9)IR

83857-96-9(2-Butyl-4-chloro-5-formylimidazole)Related Search:

tert-Butyldimethylsilyl chloride tert-Butanol butyl rubber Tetrabutylammonium bromide 1-Vinylimidazole
Butyl acetate N-(n-Butyl)thiophosphoric triamide Methimazole n-Butyllithium Buprofezin
Cyhalofop-butyl 2-Butoxyethanol 1-Bromobutane Imidazole 1H-Imidazole-4-carbaldehyde
Butyl acrylate Zolasartan Difluorochloromethane
chevron_left

1of4

chevron_right
2-BUTYL-4-CHLORO-5-IMIDAZOLECARBOXALDEHYDE (BCFI) 2-Butyl-5-formyl-4-chloroimidazole 2-butyl-5-chloro-3H-imidazole-4-carbaldehyde 2-Butyl-5-chloro-4-formylimidazole 97% 2-BUTYL-5-CHLORO-1H-IMIDAGOLE- 2-N-BUTYL-4(5)-CHLORO-1H-IMIDAZOLE-5(4)-CARBOXALDEHYDE (INTERMEDIATE OF LOSARTAN) 2-n-Butyl-4-chloro-5-formylimidazloe 2-butyl-4-chloro-5-imidazolecarboxyaldehyde 2-n-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde 2-Butyl-4(5)-chloro-1H-imidazole-5(4)-carbaldehyde 2-Butyl-5-chloro-1H-imidazole-4-carbaldehyde ,99% 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde,2-Butyl-4-chloro-5-formylimidazole 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde 97% 2-(But-1-yl)-5-chloro-1H-imidazole-4-carboxaldehyde 97% 2-(But-1-yl)-5-chloro-4-formyl-1H-imidazole Ethyl(2S)-2-[(3S,8aS)-3-Methyl-1,4-dioxo-octahydropyrrolo[1,2-alpha]pyrazin-2-yl]-4-phenylbutanoate 2-n-Butyl-4(5)-Chloro-1H-IMidazole-5(4)-Carboxaldehyde (BCFI) 2-Butyl-4-chloro-5-formylimidazole,99% LOSARTAN INTERMEDIATES 2-n-butyl-4(5)-Chloro-1H-imdazole-5(4)-carboxaldehyde 2-Butyl-5-chloro-4-formylimidazole 2-Butyl-5-choloro-1H-imidazole-4-carbaldehyde 2-Butyl-4-chloro-5-imidazolecarboxaldehyde 2-Butyl-5-Chloro-1H-Imidagole-4-Carbaldehyde 2-Buty1-4(5)-Chloro-5(4)Imidazolecarboxaldehyde 2N-Butyl-4(5)-Chloro-1H-Imidazole-5(4)-Oarboxaldehyde 2-BUTYL-5-CHLOROIMIDAZOLE-4-CARBOXALDEHYDE 2-BUTYL-4-CHLORO-IMIDAZOLE-5-CARBALDEHYDE 2-BUTYL-5-CHLORO-1H-IMIDAZOLE-4-CARBOXALDEHYDE 2-BUTYL-4-CHLORO-1H-IMIDAZOLE-5-CARBOXALDEHYDE 2-BUTYL-4-CHLORO-5-FORMYLIMIDAZLOE 2-BUTYL-4-CHLORO-5-FORMYLIMIDAZOLE 2-BUTYL-4(5)-CHLORO-5(4)IMIDAZOLECARBOXALDEHYDE 2-N-BUTYL-5-CHLORO-4-FORMYL IMIDAZOLE 2-N-BUTYL-4(5)-CHLORO-1H-IMIDAZOLE-5(4)-CARBOXALDEHYDE 2-N-BUTYL-4-CHLORO-5-FORMYLIMIDAZOLE 2-N-BUTYL-4-CHLOROIMIDAZOLE-5-CARBOXALDEHYDE 2-Butyl-5-chloro-1H-imidazole carboxaldehyde 2-Butyl-4(5)-chloro-5(4)-imidazolecarboxyaldehyde Losartan EP IMpurity D 2- butyl-4-chloro -5-forMyl iMidazoles (2-n-Butyl-5-chloro-imidazole-4-yl)-carboxaldehyde 2-Butyl-4-chloro-5-formylimidazole (BCFI) 2-N-Butyl-4-chloro-5-Formyl Imidazole (BCFI) Losartan potassium-1 2-(But-1-yl)-5-chloro-1H-imidazole-4-carboxaldehyde Losartan potassium impurity A ALSTint-A03 Losaint-A Losartan Impurity D (EP) Losartan Impurity 4(Losartan EP Impurity D) Losartan Potassium EP Impurity D Losartan impurity D CRS 2-Butyl-4-chloro-1H-imidazole-5-car 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde > 1H-Imidazole-4-carboxaldehyde, 2-butyl-5-chloro- 2-Butyl-4-chloro-5-formylimidazole USP/EP/BP 2-Butyl-4-Chloro-5-Formyl-1H-Imidazole (BCFI)