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2-Butyl-4-chloro-5-formylimidazole

CAS No.: 83857-96-9

Chemical Name:: 2-Butyl-4-chloro-5-formylimidazole

Synonyms: BCFI;2-BUTYL-4-CHLORO-1H-IMIDAZOLE-5-CARBALDEHYDE;2-BUTYL-5-CHLORO-1H-IMIDAZOLE-4-CARBALDEHYDE;2-Butyl-4-chloroimidazole-5-carboxaldehyde;Losaint-A;ALSTint-A03;Losartan potassium-1;LOSARTAN INTERMEDIATES;Losartan EP IMpurity D;Losartan impurity D CRS

CBNumber:: CB4185349

Molecular Formula:: C8H11ClN2O

Molecular Weight:: 186.64

MOL File:: 83857-96-9.mol

MSDS File:: SDS

Modify Date:: 2024/3/27 14:44:20

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2-Butyl-4-chloro-5-formylimidazole Properties

Melting point	97-100 °C(lit.)
Boiling point	384.1±22.0 °C(Predicted)
Density	1.240
vapor pressure	0.001Pa at 25℃
storage temp.	Inert atmosphere,2-8°C
solubility	soluble in methanol
form	Powder to crystal
pka	8.87±0.10(Predicted)
color	Pale Yellow to Brown
Water Solubility	slightly soluble
InChIKey	JLVIHQCWASNXCK-UHFFFAOYSA-N
LogP	2.5 at 25℃ and pH7.1
Surface tension	58.3mN/m at 1.2g/L and 20℃
CAS DataBase Reference	83857-96-9(CAS DataBase Reference)
EPA Substance Registry System	2-Butyl-5-chloroimidazole-4-carbaldehyde (83857-96-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H317-H411

Precautionary statements

P261-P272-P273-P280-P302+P352-P333+P313

Hazard Codes

Xi,N

Risk Statements

43-51/53

Safety Statements

24-37-61

RIDADR

UN 3077 9/PG 3

WGK Germany

HazardClass

IRRITANT

PackingGroup

III

HS Code

29339900

NFPA 704

	0
2		0

2-Butyl-4-chloro-5-formylimidazole price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	559881	2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde 97%	83857-96-9	25G	₹13379.7	2022-06-14	Buy
TCI Chemicals (India)	B2914	2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde min. 98.0 %	83857-96-9	25G	₹9800	2022-05-26	Buy

Product number	Packaging	Price	Buy
559881	25G	₹13379.7	Buy
B2914	25G	₹9800	Buy

2-Butyl-4-chloro-5-formylimidazole Chemical Properties,Uses,Production

Description

2-Butyl-4-chloro-5-formylimidazole is an API intermediate used as an intermediate for the anti-hypertensive drug Chlosartan. It can be used in the chemical manufacture of many APIs and advanced intermediates. With the help of this chemical, a number of other chemicals can be manufactured that have further applications in industries such as Losartan manufacturing.

Chemical Properties

2-Butyl-4-chloro-5-formylimidazole is Yellow Solid

Uses

2-Butyl-4-chloro-5-formylimidazole is used for preparation of N-(biphenylylmethyl)imidazoles as angiotensin II antagonists

Application

2-Butyl-4-chloro-1H-imidazole-5-carboxaldehyde (Losartan EP Impurity D) is used for preparation of N-(biphenylylmethyl)imidazoles as angiotensin II antagonists. Losartan USP Related Compound A.

Synthesis

2-Butyl-4-chloro-5-formylimidazole was synthesised as follows: Performing condensation reaction of pentamidine hydrochloride with glyoxal and controlling the pH value of the system in the range of 6.0-7.5; after the reaction terminates, arousing dehydration reaction of the compound of formula III, thereby obtaining 2-butyl-1H-imidazole-5(4H)-ketone; and finally, reacting 2-butyl-1H-imidazole-5(4H)-ketone with N,N-dimethylformamide in the presence of phosphorus oxychloride, thereby obtaining 2-butyl-4-chloro-5-formylimidazole.

storage

2-Butyl-4-chloro-5-formylimidazole is soluble in DMF, DMSO, Ethanol and Methanol.

2-Butyl-4-chloro-5-formylimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL EPROSARTAN N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde

2-Butyl-4-chloro-5-formylimidazole Suppliers

Global( 551)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
GLR Innovations	+91 9891111994	New Delhi, India	4542	58	Inquiry
VASISTA LIFE SCIENCES PRIVATE LIMITED	+91-04029554774 +91-9010855544	Hyderabad, India	153	58	Inquiry
Biosyn Research Chemicals	+91-91-9346022300 +91-9346022300	Telangana, India	465	58	Inquiry
Indo Amines Ltd	+91-7045592702 +91-7045592702	Mumbai, India	42	58	Inquiry
Vijayasri Organics Private Limited	+91-9848990113 +91-9848990113	Telangana, India	43	58	Inquiry
GSV speciality chemicals	+91-91823634932 +91-91823634932	Hyderabad, India	116	58	Inquiry
SNECOFRi Pvt Ltd	+91-9032850129 +91-9032850129	Telangana, India	404	58	Inquiry
GLP Pharma Standards	+91 9866074638	Hyderabad, India	1644	58	Inquiry
KARPSCHEM LABORATORIES	+91-7249203006 +91-7249203006	Maharashtra, India	786	58	Inquiry
VINEET LABORATORIES LIMITED	+91-9642200049 +91-9642200049	Telangana, India	69	58	Inquiry

Supplier	Advantage
GLR Innovations	58
VASISTA LIFE SCIENCES PRIVATE LIMITED	58
Biosyn Research Chemicals	58
Indo Amines Ltd	58
Vijayasri Organics Private Limited	58
GSV speciality chemicals	58
SNECOFRi Pvt Ltd	58
GLP Pharma Standards	58
KARPSCHEM LABORATORIES	58
VINEET LABORATORIES LIMITED	58

2-Butyl-4-chloro-5-formylimidazole Spectrum

2-Butyl-4-chloro-5-formylimidazole(83857-96-9)IR

83857-96-9(2-Butyl-4-chloro-5-formylimidazole)Related Search:

tert-Butyldimethylsilyl chloride tert-Butanol butyl rubber Tetrabutylammonium bromide 1-Vinylimidazole

Butyl acetate N-(n-Butyl)thiophosphoric triamide Methimazole n-Butyllithium Buprofezin

Cyhalofop-butyl 2-Butoxyethanol 1-Bromobutane Imidazole Butyl acrylate

1H-Imidazole-4-carbaldehyde Zolasartan Difluorochloromethane

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2-BUTYL-4-CHLORO-5-IMIDAZOLECARBOXALDEHYDE (BCFI) 2-Butyl-5-formyl-4-chloroimidazole 2-butyl-5-chloro-3H-imidazole-4-carbaldehyde 2-Butyl-5-chloro-4-formylimidazole 97% 2-BUTYL-5-CHLORO-1H-IMIDAGOLE- 2-N-BUTYL-4(5)-CHLORO-1H-IMIDAZOLE-5(4)-CARBOXALDEHYDE (INTERMEDIATE OF LOSARTAN) 2-n-Butyl-4-chloro-5-formylimidazloe 2-butyl-4-chloro-5-imidazolecarboxyaldehyde 2-n-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde 2-Butyl-4(5)-chloro-1H-imidazole-5(4)-carbaldehyde 2-Butyl-5-chloro-1H-imidazole-4-carbaldehyde ,99% 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde,2-Butyl-4-chloro-5-formylimidazole 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde 97% 2-(But-1-yl)-5-chloro-1H-imidazole-4-carboxaldehyde 97% 2-(But-1-yl)-5-chloro-4-formyl-1H-imidazole Ethyl(2S)-2-[(3S,8aS)-3-Methyl-1,4-dioxo-octahydropyrrolo[1,2-alpha]pyrazin-2-yl]-4-phenylbutanoate 2-n-Butyl-4(5)-Chloro-1H-IMidazole-5(4)-Carboxaldehyde (BCFI) 2-Butyl-4-chloro-5-formylimidazole,99% LOSARTAN INTERMEDIATES 2-n-butyl-4(5)-Chloro-1H-imdazole-5(4)-carboxaldehyde 2-Butyl-5-chloro-4-formylimidazole 2-Butyl-5-choloro-1H-imidazole-4-carbaldehyde 2-Butyl-4-chloro-5-imidazolecarboxaldehyde 2-Butyl-5-Chloro-1H-Imidagole-4-Carbaldehyde 2-Buty1-4(5)-Chloro-5(4)Imidazolecarboxaldehyde 2N-Butyl-4(5)-Chloro-1H-Imidazole-5(4)-Oarboxaldehyde 2-BUTYL-5-CHLOROIMIDAZOLE-4-CARBOXALDEHYDE 2-BUTYL-4-CHLORO-IMIDAZOLE-5-CARBALDEHYDE 2-BUTYL-5-CHLORO-1H-IMIDAZOLE-4-CARBOXALDEHYDE 2-BUTYL-4-CHLORO-1H-IMIDAZOLE-5-CARBOXALDEHYDE 2-BUTYL-4-CHLORO-5-FORMYLIMIDAZLOE 2-BUTYL-4-CHLORO-5-FORMYLIMIDAZOLE 2-BUTYL-4(5)-CHLORO-5(4)IMIDAZOLECARBOXALDEHYDE 2-N-BUTYL-5-CHLORO-4-FORMYL IMIDAZOLE 2-N-BUTYL-4(5)-CHLORO-1H-IMIDAZOLE-5(4)-CARBOXALDEHYDE 2-N-BUTYL-4-CHLORO-5-FORMYLIMIDAZOLE 2-N-BUTYL-4-CHLOROIMIDAZOLE-5-CARBOXALDEHYDE 2-Butyl-5-chloro-1H-imidazole carboxaldehyde 2-Butyl-4(5)-chloro-5(4)-imidazolecarboxyaldehyde Losartan EP IMpurity D 2- butyl-4-chloro -5-forMyl iMidazoles (2-n-Butyl-5-chloro-imidazole-4-yl)-carboxaldehyde 2-Butyl-4-chloro-5-formylimidazole (BCFI) 2-N-Butyl-4-chloro-5-Formyl Imidazole (BCFI) Losartan potassium-1 2-(But-1-yl)-5-chloro-1H-imidazole-4-carboxaldehyde Losartan potassium impurity A ALSTint-A03 Losaint-A Losartan Impurity D (EP) Losartan Impurity 4(Losartan EP Impurity D) Losartan Potassium EP Impurity D Losartan impurity D CRS 2-Butyl-4-chloro-1H-imidazole-5-car 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde > 1H-Imidazole-4-carboxaldehyde, 2-butyl-5-chloro- 2-Butyl-4-chloro-5-formylimidazole USP/EP/BP 2-Butyl-4-Chloro-5-Formyl-1H-Imidazole (BCFI)