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EPROSARTAN

CAS No.: 133040-01-4

Chemical Name:: EPROSARTAN

Synonyms: Teveten;Navixen;CS-1951;EPROSARTAN;SKB 108566;SKF-108566J;SKF-108566);Eprosartan-d4;prop-1-en-1-yl);13C6]-Eprosartan

CBNumber:: CB0135346

Molecular Formula:: C23H24N2O4S

Molecular Weight:: 424.51

MOL File:: 133040-01-4.mol

MSDS File:: SDS

Modify Date:: 2023/4/23 13:52:06

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EPROSARTAN Properties

Melting point	250-253°C
storage temp.	Sealed in dry,2-8°C
solubility	Dichloromethane (Slightly), Methanol (Slightly)
form	Solid
color	Pale Yellow to Light Yellow
CAS DataBase Reference	133040-01-4

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P305+P351+P338

EPROSARTAN Chemical Properties,Uses,Production

Description

Teveten was launched in Germany for the treatment of hypertension. There are several ways in which it has been prepared, the shortest of which is four steps; beginning with displacement of 2-butyl-4-chloroimidazole-5-carboxaldehyde with methyl 4-(bromomethyl)benzoate. Teveten is an angiotensin Ⅱ antagonist selective for the AT, subtype receptor. It is a potent, highly selective, competitve antagonist with no agonist activity. Duration of action is similar to Enalapril (greater than 12 hr) but Teveten had a faster onset. While it is orally active, it rapidly dissociates from the receptor. This is contrary to its prolonged duration of action, which presumably results from slow removal from compartments within tissue, cells or matrix around the AT, receptor. It is not bound by BSA.

Chemical Properties

Light-Yellow Solid

Uses

Eprosartan (E590100) impurity.

Definition

ChEBI: A member of the class of imidazoles and thiophenes that is an angiotensin II receptor antagonist used for the treatment of high blood pressure.

EPROSARTAN Preparation Products And Raw materials

Raw materials

Clotrimazole Methyl 4-(bromomethyl)benzoate 2-Carbethoxy-3-(2-thienyl)propanoic acid Methyl acrylate 1H-Imidazole-5-propanoic acid, 2-butyl-β-hydroxy-1-[[4-(methoxycarbonyl)phenyl]methyl]-α-(2-thienylmethyl)-, methyl ester

133040-02-5 METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE Methyl (E)-3-[2-Butyl-1-[(4-Carbomethoxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoate Eprosartan Ethyl Methyl Diester Methyl-3-(2-thienyl)=propionate

2-Butyl-4-chloro-5-formylimidazole

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Preparation Products

EPROSARTAN Suppliers

Global( 123)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
KARPSCHEM LABORATORIES	+91-7249203006 +91-7249203006	Maharashtra, India	786	58	Inquiry
OCEAN TRADING CORPORATION	+91(22) 24921669	New Delhi, India	6211	58	Inquiry
Medilink Pharmachem	+91 (79) 3007-0133	New Delhi, India	424	50	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Chiral Biosciences Limited	09441920381	Mallapur, India	41	58	Inquiry
MS Pharmachem	08048371669Ext 537	Mumbai, India	13	58	Inquiry
M/S Vijayasri Organics Private Limited	08069033724Ext 430	Hyderabad, India	7	58	Inquiry
Vijayasri Organics Limited	08068442229Ext 425	Hyderabad, India	10	58	Inquiry

Supplier	Advantage
KARPSCHEM LABORATORIES	58
OCEAN TRADING CORPORATION	58
Medilink Pharmachem	50
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Chiral Biosciences Limited	58
MS Pharmachem	58
M/S Vijayasri Organics Private Limited	58
Vijayasri Organics Limited	58

133040-01-4(EPROSARTAN)Related Search:

SB 206328 CINITAPRIDE HYDROGEN TARTRATE 4-(2-BUTYL-5-FORMYLIMIDAZOL-1-YLMETHYL)BENZOIC ACID Tacrolimus Losartan potassium

Pregabalin Irbesartan Valsartan Eprosartan mesylate Olmesartan Medoxomil

Tasosartan 4-Bromomethylbenzoic acid SB 201972 3-(2-THIENYL)PROPIONIC ACID Methyl (E)-3-[2-Butyl-1-[(4-Carbomethoxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoate

Epalrestat iMpurity 4-(Hydroxymethyl)benzoic acid α-Methylcinnamaldehyde

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4-[2-Butyl-5-(2-carboxy-3-thiophen-2-yl-propenyl)-imidazol-1-ylmethyl]-benzoic acid EPROSARTAN Eprosartan Mysylate (E)-3-[2-Butyl-1-[(4-carboxyphenyl)-methyl]imidazol-5-l]-2-(2-thienylmethyl)-2-propenoic Acid ((E)-3-[2-Butyl-1-[(4-carboxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoic Acid SKF-108566) SKF-108566J Teveten (E)- α-[[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-y1]methylene]2-thiophenepropanoic acid (E)-3-[2-Butyl-1-(4-carboxybenzyl)-1H-imidazol-5-yl]-2-(2-thienylmethyl)acrylic acid 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)- Des[2-(2-thienylMethyl)] Eprosartan-2-carboxylic Acid (E)-2-Butyl-1-(p-carboxybenzyl)-α-2-thenyliMidazole-5-acrylic Acid (αE)-α-[[2-Butyl-1-[(4-carboxyphenyl)Methyl]-1H-iMidazol-5-yl]Methylene]-2-thiophenepropanoic Acid Navixen SKB 108566 2-[[2-Butyl-1-[[4-(carboxyphenyl)]Methyl]-1H-iMidazol-5-yl]Methylene]propanedioic Acid 4-[[2-Butyl-5-(2,2-dicarboxyvinyl)-1H-iMidazol-1yl)Methylbenzoic Acid Eprosartan-d4 (E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-iMidazol-1-yl)Methyl)benzoic acid -1H-imidazol-1-yl) -4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl) prop-1-en-1-yl) CS-1951 EPROSARTAN USP/EP/BP Eprosartan D6 HClQ: What is Eprosartan D6 HCl Q: What is the CAS Number of Eprosartan D6 HCl Q: What is the storage condition of Eprosartan D6 HCl Q: What are the applications of Eprosartan D6 HCl EprosartanQ: What is Eprosartan Q: What is the CAS Number of Eprosartan Q: What is the storage condition of Eprosartan Q: What are the applications of Eprosartan TIANFU-CHEM EPROSARTAN Eprosartan (SKF-108566J) 13C6]-Eprosartan Eprosartan (E)-3-[2-Butyl-1-[(4-carboxyphenyl)methyl]-imidazol-5-yl]-2-(2- thienyl methyl)-2-propenoic acid 133040-01-4 C23H24N2O4S Aromatics Heterocycles Impurities Intermediates Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds