ChemicalBook > Product Catalog >API >Nervous system drugs >Antiepileptic and anticonvulsant >Pregabalin
Pregabalin
- CAS No.
- 148553-50-8
- Chemical Name:
- Pregabalin
- Synonyms
- Pregablin;Pregabilin;3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;Pregabali;PREDNISOLONESODIUMPHOSPHATE;PREGABAIN;Prebagalin;1-pregabalin;Pregabalin CRS;3-(Aminomethyl)-5-methyl-hexanoic acid
- CBNumber:
- CB2251105
- Molecular Formula:
- C8H17NO2
- Molecular Weight:
- 159.23
- MOL File:
- 148553-50-8.mol
- Modify Date:
- 2024/8/8 18:06:34
| Melting point | 194-196°C |
|---|---|
| alpha | D23 +10.52° (c = 1.06 in water) |
| Boiling point | 274.0±23.0 °C(Predicted) |
| Density | 0.997±0.06 g/cm3(Predicted) |
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | deionized water: ≥10mg/mL |
| pka | 4.23±0.10(Predicted) |
| form | white powder |
| Water Solubility | Soluble to 100 mM in water |
| BCS Class | 1 |
| InChI | InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1 |
| InChIKey | AYXYPKUFHZROOJ-ZETCQYMHSA-N |
| SMILES | C(O)(=O)C[C@@H](CN)CC(C)C |
| CAS DataBase Reference | 148553-50-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H336-H361 | |||||||||
| Precautionary statements | P201-P202-P261-P271-P280-P308+P313 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 63-48/22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 22-36/37-45-16-7 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29224999 | |||||||||
| NFPA 704 |
|
Pregabalin price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML3167 | Pregabalin ≥95% (HPLC) | 148553-50-8 | 10MG | ₹8053.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML3167 | Pregabalin ≥95% (HPLC) | 148553-50-8 | 50MG | ₹32496.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P-120 | Pregabalin solution 10.0?mg/mL in water, ampule of 1?mL, certified reference material, Cerilliant? | 148553-50-8 | 1ML | ₹52815.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P-066 | Pregabalin solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 148553-50-8 | 1ML | ₹18659.9 | 2022-06-14 | Buy |
Pregabalin Chemical Properties,Uses,Production
Description
Pregabalin (Lyrica), a derivative of GABA that is closely related to gabapentin, has undergone extensive research for its efficacy in treating conditions such as generalized anxiety disorder (GAD), fibromyalgia, neuropathic pain, and partial complex seizures. It seems to have a more targeted effect on the a2-δ subunit of calcium channels in the brain compared to gabapentin. Pregabalin was granted FDA approval at the end of 2004 for the treatment of neuropathic pain and epilepsy. In 2008, it became the first medication approved for the management of fibromyalgia. Although pregabalin was approved for GAD treatment in the European Union in 2006, it has not yet received FDA approval for GAD in the United States as of the time of writing.
Chemical Properties
Off-White Solid
Uses
S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
General Description
Pregabalin, marketed as the anticonvulsant drug Lyrica, is used in the treatment of epilepsy and generalized anxiety disorder. Along with other anticonvulsants such as gabapentin and levetiracetam, pregabalin is also used to treat neuropathic pain. This certified reference standard is suitable for pregabalin GC/MS or LC/MS applications from forensic analysis, clinical toxicology and pain prescription monitoring to urine drug testing.
Pregabalin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 866)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Cadila Pharmaceuticals Ltd | +91-7069076657 +91-7069076657 | Ahmedabad, India | 54 | 58 | Inquiry |
| NILKANTH HEALTH CHEM (I) PRIVATE LIMITED | +91 8000452862 | Gujarat, India | 17 | 58 | Inquiry |
| ANWITA APIS | +919000311012 | Hyderabad, India | 198 | 58 | Inquiry |
| Dr. Reddy's Laboratories Ltd | +91-4049002900 +91-4049002900 | Hyderabad, India | 165 | 58 | Inquiry |
| ChemBioReas Life Sciences | +91-7989264158 +91-7989264158 | Hyderabad, India | 82 | 58 | Inquiry |
| VASISTA LIFE SCIENCES PRIVATE LIMITED | +91-04029554774 +91-9010855544 | Hyderabad, India | 153 | 58 | Inquiry |
| SGMR PHARMACEUTICALS PVT LTD | +91-9032001889 +91-9032001889 | Telangana, India | 83 | 58 | Inquiry |
| ALMELO PRIVATE LIMITED | +91-9100991345 +91-8500807769 | Telangana, India | 114 | 58 | Inquiry |
| THE MOLECULEZ | +91-7506703683 +91-7506703683 | Maharashtra, India | 79 | 58 | Inquiry |
Related articles
- Pregabalin vs. Gabapentin: similarities and differences
- Pregabalin and Gabapentin are both classified as anticonvulsants or antiepileptic drugs (AEDs) and are both used to treat part....
- Jun 7，2024
- Side effects of taking pregabalin
- Pregabalin is a drug that has been approved for different indications across the world, including the treatment of pain syndro....
- Feb 18，2024
- Uses and Preparation of Pregabalin
- Pregabalin is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and....
- Jul 5，2022
148553-50-8(Pregabalin)Related Search:
chevron_left
1of4
chevron_right
PREGABALIN
(R)-Pregabalin
(S)-Pregabalin
(S)-3-(Ammoniomethyl)-5-methylhexanoate
3(S)-(AMINOMETHYL)-5
Pregabalin-13C3 RaceMic
PREGABALINE (S)-(+)-3-AMinoMethyl-5-Methylhexanoic acid
(S)-(+)-Pregabalin-d4
xiangxizhiliao
Pregabalin (S)-(+)-3-AMinoMethyl-5-Methylhexanoic acid
(S)-Pregabalin (1.0 Mg/ML in Methanol)
Pregabalin SynonyMs 3-(AMinoMethyl)-5-Methyl-hexanoic acid
Pregabalin
3-(Aminomethyl)-5-methyl-hexanoic acid
Pregabalin solution
Hexanoic acid, 3-(aminomethyl)-5-methyl-, (3S)-
Pregabalin and Intermediates
Pregabalin kf-wang(at)kf-chem.com
API Pregabalin 148553-50-8 wickr alinalee
(S)-3-(Aminomethyl)-5-methylhexanoic acid (Pregabalin)
Neugaba 75
Maxgalin 75
Pregabalin Manufacturer
ACTIVE PHARMACEUTICALS INGRADIENTS : PRE GABALIN 3-( AMINOMETHYL)-5-METHYL-HEXANO IC ACID (OTHER) [TAX I
Pregabalin powder 99%
APIPregabalin
Pregabalin powder
3-(aminomethyl)-5-methyl-(3S)-Hexanoic acid
TOS-BB-0910
Pregabalin Lyric Pregablin
Prebagalin for sale
Pregabalin Basic information
Pregabalin USP/EP/BP
pure pregabalin
(S)(+)-3-Aminomethyl-5-methyl-hecanoic acid
crystal Pregabalin
Pregabalin -IP/IH/USP/EP
prégabaline
Pregabalin #69-1 gram
Pregabalin (Y0001805)Q: What is
Pregabalin (Y0001805) Q: What is the CAS Number of
Pregabalin (Y0001805)
Pregabalin D6
PregabalinQ: What is
Pregabalin Q: What is the CAS Number of
Pregabalin Q: What is the storage condition of
Pregabalin Q: What are the applications of
Pregabalin
Pregabalin CV (1559618)
pregabalin crystal
3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID
(3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID
Pregablin
3-(Aminomethyl)-5-methyl-hexanoic acid
PREDNISOLONESODIUMPHOSPHATE
Pregabilin
Pregabalin CRS
Prebagalin
Pregabali
PREGABAIN
1-pregabalin
Pregabalin C8H17NO2
Pregabalin (CRM)
Pregabalin
IP/BP/EP/USP
Prybalin