ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >AChR antagonist >Trospium chloride
Trospium chloride
- CAS No.
- 10405-02-4
- Chemical Name:
- Trospium chloride
- Synonyms
- Trospium;Trosupium Chloride;Sanctura;asxvii;keptan;spasmex;spasmo3;relaspium;Spasmo-lyt;trospiuM-D8
- CBNumber:
- CB6481397
- Molecular Formula:
- C25H30ClNO3
- Molecular Weight:
- 427.96
- MOL File:
- 10405-02-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:14
| Melting point | 266-268°C |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Very soluble in water, freely soluble in methanol, practically insoluble in methylene chloride. |
| form | Solid |
| color | White to Off-White |
| Merck | 14,9786 |
| InChIKey | RVCSYOQWLPPAOA-QKYUOBHYSA-M |
| SMILES | [N+]12(CCCC1)[C@@]1([H])CC[C@]2([H])C[C@@H](C1)OC(=O)C(O)(C1=CC=CC=C1)C1C=CC=CC=1.[Cl-] |&1:5,9,12,r| |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| RTECS | WH1424000 | |||||||||
| HS Code | 2939800000 | |||||||||
| Toxicity | Soly in water: ~1 g/2 ml. LD50 in mice (mg/kg): 12.3 i.v. (Antweiler) | |||||||||
| NFPA 704 |
|
Trospium chloride price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR3378 | Trospium chloride certified reference material, pharmaceutical secondary standard | 10405-02-4 | 200MG | ₹30970.33 | 2022-06-14 | Buy |
| TCI Chemicals (India) | T3305 | Trospium Chloride | 10405-02-4 | 200MG | ₹6300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T3305 | Trospium Chloride | 10405-02-4 | 1G | ₹14500 | 2022-05-26 | Buy |
Trospium chloride Chemical Properties,Uses,Production
Description
Trospium chloride (Sanctura) is an antimuscarinic that has been used in Europe for the management of OAB symptoms for over 30 years.Trospium chloride's chemical structure is such that it is unlikely to penetrate the brain and thus does not appear to affect cognitive function. Trospium chloride is usually administered orally twice a day in 20mg. Trospium chloride should be taken 1 hour before meals or on an empty stomach. It is not well absorbed if taken with food.An advantage of this medication is that it has little potential interaction with other medications.
Chemical Properties
White to Off-White Crystalline Solid
Uses
Tropine derivative with anticholinergic activity, Trospium chloride can be used as Antispasmodic and used in treatment of urinary incontinence
General Description
Trospium chloride, 3α-benziloyloxynortropane-8-spiro-1'-pyrrolidinium chloride, (Sanctura) was available in Europe for almost 20 years before gainingapproval in the United States in May 2004. Much likeoxybutynin, it too is a competitive antagonist for muscarinicreceptors and is used to manage overactive bladder. Thequaternary amine reduces the likelihood that this agent willcross the blood-brain barrier. In addition, it has a limitedmetabolic profile, largely a result of its highly water-solublecharacteristics.
Trospium chloride Preparation Products And Raw materials
Raw materials
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Global( 322)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Apotex Pharmachem India Pvt Ltd | +91-8022891034 +91-8022891000 | Karnataka, India | 109 | 58 | Inquiry |
| Macleods Pharmaceuticals Limited | +91-2266762800 +91-2266762800 | Maharashtra, India | 116 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Fleming Laboratories Ltd | +91-9666407333 +91-9666022445 | Hyderabad, India | 22 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| ProVentus Life Sciences Pvt Ltd | +91-4428362047 +91-4447400141 | Tamil Nadu, India | 20 | 58 | Inquiry |
| Enaltec Labs Pvt Ltd | +91-9167119247 +91-9167119247 | Maharashtra, India | 49 | 58 | Inquiry |
| Zeon Pharma | +91 22 64405325 | Maharashtra, India | 16 | 58 | Inquiry |
| Aspart Chemicals | 07984983327 | Gujarat, India | 4 | 58 | Inquiry |
Related articles
- Trospium Chloride: Therapeutic Efficacy, Dosage and Administration
- Trospium chloride effectively reduces overactive bladder symptoms, supported by robust clinical evidence, with dosage adjustme....
- Apr 9，2024
- Trospium chloride: Biological action, Pharmacodynamics, and Pharmacokinetics
- Trospium chloride, a quaternary amine with anticholinergic properties, is used for the treatment of overactive bladder with sy....
- Oct 31，2023
10405-02-4(Trospium chloride)Related Search:
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(1a,3,5a)-3-[(2-Hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] Chloride
5-alpha-h-nortropane-8,1’-pyrrolidinium),3-alpha-hydroxy-spiro(1-alpha-chl
8-alpha-benziloyloxy-6,10-ethano-5-azoniaspiro(4.5)decanechloride
asxvii
azoniaspiro(3-alpha-benziloyloxy-nortropan-8,1’-pyrrolidine)-chloride
azoniaspirocompoundxvii
keptan
Trosipium Chloride
Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium], 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-, chloride (1:1), (1a,3b,5a)-
Trospium Chloride (100 mg)
trospiuM-D8
TrospiuM chloride (Sanctura)
(1α,3β,5α)-3-[(2-Hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidiniuM] Chloride
(1α,3β,5α)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium],chloride (1:1)
Trospium chloride, >=99%
oride,benzilate
relaspium
spasmex
spasmo3
TROSPIUM CHLORIDE
(1a,3b,5a)-3-[(2-Hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] Chloride
Azoniaspiro
Azoniaspiro(3a-benziloyloxynortropane-8,1'-pyrrolidine) chloride
Benzilic acid, ester with 3a-hydroxyspiro[1aH,5aH-nortropane-8,1'-pyrrolidinium] chloride (8CI)
Spasmo-lyt
Spiro[1aH,5aH-nortropane-8,1'-pyrrolidinium], 3a-hydroxy-, chloride, benzilate (8CI)
Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium], 3-[(hydroxydiphenylacetyl)oxy]-, chloride, (1a,3b,5a)- (9CI)
Trospiumchlorid
TROSPIUM CHLORDE
2-hydroxy-2,2-diphenylacetic acid [(1S,5R)-3-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]yl] ester chloride
Trospium chloride CRS
rel-(1R,3r,5S)-3-(2-Hydroxy-2,2-diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-1'-ium chloride
Trospium chloride USP/EP/BP
Trospium chlorideQ: What is
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Trospium chloride Q: What are the applications of
Trospium chloride
Trospium-d8 chlorideQ: What is
Trospium-d8 chloride Q: What is the CAS Number of
Trospium-d8 chloride Q: What is the storage condition of
Trospium-d8 chloride Q: What are the applications of
Trospium-d8 chloride
Trospium Chloride (1699300)
Sanctura
Trospium
Trosupium Chloride
13C6]-Trospium chloride salt
rel-(1R,3r,5S)-3-(2-Hydroxy-2,2-diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-1'-ium chloride
10405-02-4
10405024
C25H30ClNO3
C25H30NO3Cl
C25H30NO3
AGRI-MEK
Intermediates & Fine Chemicals
Pharmaceuticals
10405-02-4