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Trospium chloride

Trospium Chloride

CAS:
10405-02-4
MF:
C25H30ClNO3
MW:
427.96

Properties

Melting point:
266-268°C
storage temp. 
Inert atmosphere,2-8°C
solubility 
Very soluble in water, freely soluble in methanol, practically insoluble in methylene chloride.
form 
Solid
color 
White to Off-White
Merck 
14,9786
InChIKey
RVCSYOQWLPPAOA-QKYUOBHYSA-M
SMILES
[N+]12(CCCC1)[C@@]1([H])CC[C@]2([H])C[C@@H](C1)OC(=O)C(O)(C1=CC=CC=C1)C1C=CC=CC=1.[Cl-] |&1:5,9,12,r|

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H302
Precautionary statements 
P301+P312+P330
RTECS 
WH1424000
HS Code 
2939800000
Toxicity
Soly in water: ~1 g/2 ml. LD50 in mice (mg/kg): 12.3 i.v. (Antweiler)

Use

Trospium chloride is a quaternary ammonium compound that is nonselective for the muscarinic receptor. It also has smooth muscle relaxant qualities.(Staskin et al.,2007) Trospium chloride is available in an lR formulation given 20 mg twice daily or an ER formula administered 60 mg daily. The uniqueness of this antimuscarinic is that it is renally cleared.Care should be used in the elderly and patients with renal impairment. The initial dosing in these patients she be the IR formulation 20 mg once daily. The ER formulation should not be used in patients with severe renal impairment. Because of poor bioavailability, trospium chloride must be taken on an empty stomach.

28 India supplier list of "Trospium Chloride"

  • Product Name:Trospium chloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Tamil Nadu,INDIA
  • Product Name:Trospium chloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Trospium chloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Trospium chloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Trospium chloride
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Trospium chloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1MT
  • Company Type: Manufacturer
  • Country/Region: Karnataka,INDIA
  • Product Name:Trospium chloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:Trospium chloride
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Trospiumchloride
  • Products Intro:Brand:sigma aldrich | Product Number:PHR3378 | Purity:certifiedreferencematerial,pharmaceuticalsecondarystandard
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Trospium chloride 98% (HPLC)
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.040342
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA

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