Tris(hydroxymethyl)aminomethane
Tris(hydroxymethyl)aminomethane
- CAS:
- 77-86-1
- MF:
- C4H11NO3
- MW:
- 121.14
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Properties
- Melting point:
- 167-172 °C(lit.)
- Boiling point:
- 219-220 °C10 mm Hg(lit.)
- Density
- 1,353 g/cm3
- vapor pressure
- 0.0267 hPa (20 °C)
- refractive index
- 1.4170 (estimate)
- Flash point:
- 219-220°C/10mm
- storage temp.
- 20-25°C
- solubility
- H2O: 4 M at 20 °C, clear, colorless
- form
- crystalline
- color
- white
- PH Range
- 7 - 9
- PH
- 10.5-12.0(4 m in water, 25 °C)
- pka
- 8.1(at 25℃)
- Water Solubility
- 550 g/L (25 ºC)
- λmax
- λ: 260 nm Amax: 0.10
λ: 280 nm Amax: 0.08
- Sensitive
- Hygroscopic
- Merck
- 14,9772
- BRN
- 741883
- Stability:
- Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
- InChIKey
- LENZDBCJOHFCAS-UHFFFAOYSA-N
- LogP
- -2.515 (est)
- CAS DataBase Reference
- 77-86-1(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
- EPA Substance Registry System
- Tris(hydroxymethyl)aminomethane (77-86-1)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39-24/25-23
- WGK Germany
- 2
- RTECS
- TY2900000
- F
- 3
- TSCA
- Yes
- HazardClass
- IRRITANT
- HS Code
- 29221980
- Hazardous Substances Data
- 77-86-1(Hazardous Substances Data)
- Toxicity
- LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rat > 5000 mg/kg
Use
Tris base, also known as THAM, is widely used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.
51 India supplier list of "Tris(hydroxymethyl)aminomethane"
- Product Name:Tris Base
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Tris-(hydroxymethyl)-aminomethane
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:TRIS BUFFER 99.5%
- Products Intro:Purity: 99.50% | Package: 100GM;500GM
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:TROMETHAMINE
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Tris(hydroxymethyl)aminomethane (TRIS BASE)
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Tris(hydroxymethyl)aminomethane, 98%
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Tris(hydroxymethyl)aminomethane
- Products Intro:Brand:sigma aldrich | Product Number:1.02408 | Purity:volumetricstandard,secondaryreferencematerialforacidimetry,traceabletoNISTStanda
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Tris(hydroxymethyl)aminomethane AR ACS molecular biology 99.9%
- Products Intro:Brand：Glrinnovations | OriginalID：GLRIN18226611
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Tris-(Hydroxymethyl) Aminomethane 99.9+% Ultrapure
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Tris Base
- Company Type: Trader
- Country/Region: New Delhi,INDIA