Buprofezin
![Buprofezin Structure](CAS/GIF/69327-76-0.gif)
- CAS No.
- 69327-76-0
- Chemical Name:
- Buprofezin
- Synonyms
- BUTYL;BUPROFENZIN;Buprofezine;PP618;Aproad;Appland;NNI 750;VIAPPLA;APPLAUD;BUPROLEX
- CBNumber:
- CB4436924
- Molecular Formula:
- C16H23N3OS
- Molecular Weight:
- 305.44
- MOL File:
- 69327-76-0.mol
- Modify Date:
- 2024/7/12 17:58:41
Melting point | 104-106°C |
---|---|
alpha | 22 º (c=8,6N HCl) |
Boiling point | 273°C (12 torr) |
Density | 1.18 |
vapor pressure | 1.25 x l0-3 Pa (25 °C) |
refractive index | 1.52-1.522 |
Flash point | 176-178°C |
storage temp. | 0-6°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | 3.02±0.20(Predicted) |
color | White to Pale Beige |
Water Solubility | 0.9 mg/L at 20 ºC |
Decomposition | 176-178 ºC |
BRN | 8324923 |
CAS DataBase Reference | 69327-76-0(CAS DataBase Reference) |
NIST Chemistry Reference | 4H-1,3,5-thiadiazin-4-one, 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-(69327-76-0) |
EPA Substance Registry System | Buprofezin (69327-76-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS08,GHS09 |
---|---|
Signal word | Warning |
Hazard statements | H373-H410 |
Precautionary statements | P260-P273-P314-P391-P501 |
RIDADR | UN3077(solid) |
WGK Germany | 2 |
RTECS | XI2865000 |
Toxicity | LD50 in mice, rats (mg/kg): 10000, 8740 orally; LC50 (48 hr) in carp: 2-10 mg/l (Kanno, 1981) |
Buprofezin Chemical Properties,Uses,Production
Uses
Buprofezin is a insecticide which works as a chitin synthesis inhibitor. Buprofezin is used to control stubborn rice pests and is effective in controlling green leaf hoppers and white back plant hoppe rs for long durations.
Hazard
Moderately toxic by ingestion. Low toxic- ity by skin contact.
Agricultural Uses
Insecticide, Acaricide, Insect growth regulator: For insect control in food crops and greenhouse ornamentals.
Trade name
APPLAUD®; NNI-750®
Pharmacology
The foregoing indicates that the modes of action of buprofezin and benzoylureas could be similar or identical. However, one differing biochemical effect of buprofezin is inhibition of prostaglandin biosynthesis (33), a mechanism that has been suggested as responsible for its ovicidal activity. Subsequently, the in vitro and in vivo effects of buprofezin were found to be strongly antagonized by 20- hydroxyecdysone (34), which also affected prostaglandin biosynthesis. Thus, inhibition of both prostaglandin and chitin biosynthesis by buprofezin was prevented by 20- hydroxyecdysone, so that both effects of the insecticide are mediated via an effect on the hormone concentration or its receptor. Consequently, buprofezin seems to inhibit the drop in the 20-hydroxyecdysone titer that triggers epidermal cell proliferation, old cuticle digestion, and new cuticle deposition, but the detailed mechanism of this action has yet to be established.
Metabolic pathway
Buprofezin gradually decomposes in soils under flooded and upland conditions, with half-lives of 104 and 80 days, respectively. After 150 days, five degradation products are identified as 2-tert- butylimino-5-(4-hydroxyphenyl)-3-isopropylperhydro- 1,3,5-thiadiazin-4-one, 3-isopropyl-5-phenylperhydro- 1,3,5-thiadiazin-2,4-dione, 1-tert-butyl-3-ispropyl-5- phenylbiuret, 1-isopropyl-3-phenylurea, and phenylurea. As minor products, 2-tert-butylimino-5- phenylperhydro-1,3,5-thiadiazin-4-one or buprofezin sulfoxide are found in the flooded or in the upland soils. Since neither formation of 14CO2 nor hydroxylation is observed in the sterile soils, buprofezin seems to have undergone complete mineralization in soils under both conditions through biological transformation by soil microorganisms.
Buprofezin Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Crop Life Science Limited | +91-7940373967 +91-7926872996 | Gujarat, India | 21 | 58 | Inquiry |
Insecticides Ltd | +91-1127679700 +91-1127679700 | New Delhi, India | 13 | 58 | Inquiry |
SD Agro Chemicals | +91-9650182828 +91-9871331171 | Uttar Pradesh, India | 42 | 58 | Inquiry |
General Crop Science | +91-9810438260 +91-9896700555 | Haryana, India | 31 | 58 | Inquiry |
Mangalore Chemicals And Fertilizers Limited | +91-8045855599 +91-8045855599 | Karnataka, India | 17 | 58 | Inquiry |
Shree Vallabh Chemicals | +91-8849453471 +91-9975490440 | Gujarat, India | 43 | 58 | Inquiry |
Nigam Krishi Sewa Kendra | 08048250310Ext 833 | Uttar Pradesh, India | 1 | 58 | Inquiry |
Kalyani Industries Limited | 08047639232 | Mumbai, India | 37 | 58 | Inquiry |
Crop Life Science Limited | 08048372027Ext 511 | Ahmedabad, India | 7 | 58 | Inquiry |
Umbrella Life Science | 08046073923 | Gujarat, India | 8 | 58 | Inquiry |