Ertugliflozin L-pyroglutamic acid

Ertugliflozin L-pyroglutamic acid Structure
CAS No.
1210344-83-4
Chemical Name:
Ertugliflozin L-pyroglutamic acid
Synonyms
Pidolate;ERTUGLIFLOZIN PIDOLATE;Gliadine L- pyroglutamate;L-pyroglutamate atogliflozin;PF-04971729 L-pyroglutamic acid;Ertugliflozin L-pyroglutamic acid;Ertugliflozin L-pyroglutamic Acid (1:1);Ertugliflozin L-pyroglutamic acid Impurity;PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid);SGLT,inhibit,Ertugliflozin L-pyroglutamic acid,Sodium-dependent glucose cotransporters,Inhibitor,Ertugliflozin L pyroglutamic acid,Ertugliflozin Lpyroglutamic acid
CBNumber:
CB73159894
Molecular Formula:
C27H32ClNO10
Molecular Weight:
566
MOL File:
1210344-83-4.mol
Modify Date:
2024/9/5 14:45:50

Ertugliflozin L-pyroglutamic acid Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO: ≥ 125 mg/mL (220.85 mM)
form Solid
color White to off-white
InChIKey YHIUPZFKHZTLSH-NCRAORDPNA-N
SMILES C([C@@H]1CCC(=O)N1)(=O)O.O[C@@H]1[C@H]([C@H](O)[C@]2(CO)CO[C@@]1(C1C=CC(Cl)=C(CC3C=CC(OCC)=CC=3)C=1)O2)O |&1:1,10,11,12,14,19,r|

Ertugliflozin L-pyroglutamic acid Chemical Properties,Uses,Production

Description

Ertugliflozin L-pyroglutamic acid is a potent, selective, orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor with an IC50 value of 0.877 nM for h-SGLT2.It is the main active ingredient in the tablet ertugliflozin. It is the main active ingredient of ertugliflozin tablets. It is used as an adjunctive therapy for type 2 diabetes.

Chemical Properties

Ertugliflozin L-pyroglutamic acid is a white to off-white powder, soluble in ethanol and acetone, slightly soluble in ethyl acetate and acetonitrile, and very slightly soluble in water.

Uses

Ertugliflozin L-pyroglutamic Acid is a reagent in the synthesis of Ertugliflozin (1210344-57-2) a sodium/glucose cotransporter 2 (SGLT2) inhibitor used to treat type 2 diabetes.

brand name

STEGLATRO

Ertugliflozin L-pyroglutamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 115)Suppliers
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Morepen Laboratories Ltd +91-7017029282 +91-9818305894 Haryana, India 34 58 Inquiry
Biophore India Pharmaceuticals Pvt Ltd +91-9100031592 +91-9030907714 Telangana, India 134 58 Inquiry
Metrochem API Private Limited +91-4069069999 +91-4069069999 Telangana, India 78 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 5225 58 Inquiry
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. +86-18600796368 +86-18600796368 China 212 58 Inquiry
Wuhan Fortuna Chemical Co.,Ltd +8618007136271 China 5945 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry

Ertugliflozin L-pyroglutamic acid Spectrum

PF-04971729 L-pyroglutamic acid Ertugliflozin L-pyroglutamic Acid (1:1) ERTUGLIFLOZIN PIDOLATE Pidolate PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid) (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol (1:1) compound with (S)-5-oxopyrrolidine-2-carboxylic acid (S)-5-Oxopyrrolidine-2-carboxylic acid compound with (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol (1:1) Gliadine L- pyroglutamate Ertugliflozin L-pyroglutamic acid SGLT,inhibit,Ertugliflozin L-pyroglutamic acid,Sodium-dependent glucose cotransporters,Inhibitor,Ertugliflozin L pyroglutamic acid,Ertugliflozin Lpyroglutamic acid Ertugliflozin L-pyroglutamic acid Impurity L-pyroglutamate atogliflozin 1210344-83-4