Tofogliflozin

CAS No.: 903565-83-3

Chemical Name:: Tofogliflozin

Synonyms: CSG 452;Tofogliflozin;CSG452;CSG-452;Tofogliflozin-13C6;Tofogliflozin(free);CSG452; CSG 452; CSG-452;(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol;(1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triol;(1S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-6-(methoxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol;((1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-3',4',5'-trihydroxy-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-6'-yl)methyl propionate

CBNumber:: CB52551370

Molecular Formula:: C22H26O6

Molecular Weight:: 386.44

MOL File:: 903565-83-3.mol

MSDS File:: SDS

Modify Date:: 2023/5/18 11:31:12

Request For Quotation

Tofogliflozin Properties

Melting point	75-79oC
Boiling point	607.5±55.0 °C(Predicted)
Density	1.38±0.1 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
pka	13.06±0.70(Predicted)
form	Solid
color	White to Off-White
Stability	Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

Tofogliflozin Chemical Properties,Uses,Production

Uses

A novel, potent, and highly selective SGLT2 inhibitor that has been shown to improve glycemic control in diabetic mice and rats.

Tofogliflozin Preparation Products And Raw materials

Raw materials

Preparation Products

Tofogliflozin Suppliers

Global( 75)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6700	30	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30231	58	Inquiry
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	China	9642	58	Inquiry
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	China	9304	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10473	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6391	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	China	25356	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24727	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
CHEMSWORTH	30
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Finetech Industry Limited	58
Baoji Guokang Bio-Technology Co., Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
LEAP CHEM CO., LTD.	58

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Tofogliflozin ((1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-3',4',5'-trihydroxy-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-6'-yl)methyl propionate (1S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-6-(methoxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol (1S,3'R,4'S,5'S,6'R)-6-[(4-Ethylphenyl)Methyl]-3',4',5',6'-tetrahydro-6'-(hydroxyMethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-3',4',5'-triol CSG 452 Tofogliflozin-13C6 Spiro[isobenzofuran-1(3H),2'-[2H]pyran]-3',4',5'-triol, 6-[(4-ethylphenyl)methyl]-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)-, (1S,3'R,4'S,5'S,6'R)- CSG452; CSG 452; CSG-452 (3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol CSG452;CSG-452 Tofogliflozin(free) (1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triol 903565-83-3 Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals