Ginsenoside Rg1
- CAS No.
- 22427-39-0
- Chemical Name:
- Ginsenoside Rg1
- Synonyms
- Rg1;SANCHINOSIDE C1;PANAXOSIDE A;ginsenosidea2;ginsenosideg1;panaxosiderg1;Gensenoside Rg1;GINSENOSIDE RGL;GINSENOSIDE RG1;Panaxsaponin Rg1
- CBNumber:
- CB7331840
- Molecular Formula:
- C42H72O14
- Molecular Weight:
- 801.01
- MOL File:
- 22427-39-0.mol
- Modify Date:
- 2024/7/2 8:55:16
| Melting point | 194～197℃ |
|---|---|
| Boiling point | 898.5±65.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly) |
| pka | 12.91±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChIKey | YURJSTAIMNSZAE-OLCOBRLXNA-N |
| LogP | 1.670 (est) |
| CAS DataBase Reference | 22427-39-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 2-45-36/37-16-7-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LY9537200 | |||||||||
| HS Code | 29389090 | |||||||||
| NFPA 704 |
|
Ginsenoside Rg1 price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR2200 | Ginsenoside Rg1 certified reference material, pharmaceutical secondary standard | 22427-39-0 | 50MG | ₹18510.75 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 68317 | Ginsenoside Rg1 analytical standard | 22427-39-0 | 5MG | ₹36469.43 | 2022-06-14 | Buy |
Ginsenoside Rg1 Chemical Properties,Uses,Production
Description
Ginsenoside RG1(Rg1) is a natural product found in Panax notoginseng, Panax ginseng, and Panax vietnamensis. It is one of the primary bioactive ingredients in Panax notoginseng saponins. Numerous studies have indicated that Rg1 plays significant roles in health benefits such as anticancer, neuroprotective, anti-senescence, anti-inflammation, and antioxidative effects. Also, extensive research has demonstrated that Rg1 is associated with various diseases, including cardiovascular disease, Alzheimer’s disease, spinal cord injury, and liver injury. Xue et al. and Yu et al. demonstrated that Rg1 ameliorated streptozotocin-induced oxidative stress and myocardial apoptosis and suppressed HG-induced mesenchymal activation and fibrosis[1].
Chemical Properties
White solid
Uses
Ginsenoside Rg1 protects against arthitis through osteoclast differentiation inhibition. Anti-tumor agent, inhibits the NF-kB-dependant MMP-expression in PMA (phorbol myristate acetate)-induced tumor cell invasion.
Definition
ChEBI: A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 <ital pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 posit on.
References
[1] Hui Liu. “Ginsenoside Rg1 attenuates the inflammation and oxidative stress induced by diabetic nephropathy through regulating the PI3K/AKT/FOXO3 pathway.” Annals of translational medicine 9 24 (2021): 1789.
Ginsenoside Rg1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-19164747840 +86-13119157289 | China | 2971 | 58 | Inquiry |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 1000 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16920 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9336 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29896 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
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