2-Phenylquinoline
![2-Phenylquinoline Structure](CAS/GIF/612-96-4.gif)
- CAS No.
- 612-96-4
- Chemical Name:
- 2-Phenylquinoline
- Synonyms
- 830g;2-Phenylquinoline;a-Phenylquinoline;Phenylquinoline,99%;2-Phenylquinoline>Phenylquinoline, 99%;Quinoline, 2-phenyl-;2-Phenylquinoline 99%;alpha-Phenylquinoline;2-Phenylquinoline, 99+%
- CBNumber:
- CB7408748
- Molecular Formula:
- C15H11N
- Molecular Weight:
- 205.25
- MOL File:
- 612-96-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/1/5 11:48:35
Melting point | 84-85 °C (lit.) |
---|---|
Boiling point | 363 °C |
Density | 1.1155 (rough estimate) |
refractive index | 1.6550 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
pka | 4.52±0.10(Predicted) |
form | Crystalline Powder |
color | White to light yellow |
Water Solubility | SLIGHTLY SOLUBLE |
λmax | 258nm(lit.) |
CAS DataBase Reference | 612-96-4(CAS DataBase Reference) |
NIST Chemistry Reference | Quinoline, 2-phenyl-(612-96-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-37/39 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 29334900 | |||||||||
NFPA 704 |
|
2-Phenylquinoline price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 299650 | 2-Phenylquinoline 99% | 612-96-4 | 1G | ₹5440 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 299650 | 2-Phenylquinoline 99% | 612-96-4 | 5G | ₹27020 | 2022-06-14 | Buy |
ALFA India | ALF-H31920-06 | 2-Phenylquinoline, 99+% | 612-96-4 | 5g | ₹24366 | 2022-05-26 | Buy |
ALFA India | ALF-H31920-03 | 2-Phenylquinoline, 99+% | 612-96-4 | 1g | ₹5060 | 2022-05-26 | Buy |
TCI Chemicals (India) | P2057 | 2-Phenylquinoline min. 98.0 % | 612-96-4 | 1G | ₹5200 | 2022-05-26 | Buy |
2-Phenylquinoline Chemical Properties,Uses,Production
Description
2-Phenylquinoline is the major quinoline alkaloid of Galipea iongiflora, a Bolivian plant used as treatment for cutaneous leishmaniasis. Antinociceptive properties of 2-phenylquinoline isolated from the bark of Galipea iongiflora against different models of pain in mice were evaluated.
Chemical Properties
white to light yellow crystalline powder
Preparation
Synthesis of 2-phenylquinoline: Quinoline (1.0 g, 7.742 mmol) and phenyl lithium (2.30 mL, 2 M, 23.22 mmol) were reacted according to general procedure. Purification of the residue by silica gel column chromatography (EtOAc:MeOH:Et3N; 10-30:1:1 or PhMe:MeOH:Et3N; 10:1:1) gave 2-phenylquinoline (0.66 g, 42%) as an orange solid.
Aniline (0.140 g, 1.50 mmol) and cinnamaldehyde (0.132 g, 1.00 mmol) were dissolved in toluene in a reaction vial equipped with a magnetic stirrer bar, followed by the addition of K10 (0.50 g). The reaction mixture was heated at a temperature of 110 ?C for 3 hours. After completion of the reaction, the crude product was purified by column chromatography over silica gel eluting with a mixture of Hexane : Ethyl acetate (20:1) to produce 2-Phenylquinoline as a yellow solid (0.044 g, 21%); (m.p. 82-84 ?C) (lit. 84-85 °C); Rf 0.67 (20:1 hexane:ethyl acetate);
1H NMR (400 MHz, CDCl3) δH 7.46-7.51 (1H, m, H-4’), 7.53-7.56 (3H, m, H-6, 3’, 5’), 7.73- 7.77 (1H, m, H-7), 7.85 (1H, d, J = 8.31 Hz, H-5), 7.88-7.91 (1H, d, J = 8.31 Hz, H-3), 8.18- 8.27 (4H, m, H-4, 8, 2’, 6’)
13C NMR(400 MHz, CDCl3) δC 119.2 (C-3), 126.7 (C-6), 127.2 (C-4a), 127.5 (C-2’, 6’), 127.9 (C-5), 128.4 (C-3’, 5’), 128.7 (C-4’), 128.9 (C-7, 8), 129.8 (C-4), 130.3 (C-1’), 137.9 (C-8a), 157.2 (C-2)
2-Phenylquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20308 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16209 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10318 | 58 | Inquiry |
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