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ANHYDROTETRACYCLINE HYDROCHLORIDE

ANHYDROTETRACYCLINE HYDROCHLORIDE Structure
CAS No.
13803-65-1
Chemical Name:
ANHYDROTETRACYCLINE HYDROCHLORIDE
Synonyms
AnhydrotetracyclineHCl;Tetracycline Anhydro HCl;Aureomycin EP impurity J;Anhydrotetracycline HCl, EvoPure;ANHYDROTETRACYCLINE HYDROCHLORIDE;Anhydrotetracycline hydrochloride CRS;5A,6-ANHYDROTETRACYCLINEHYDROCHLORIDE;Anhydrotetracycline hydrochloride ,97%;ANHYDROTETRACYCLINE HYDROCHLORIDE USP/EP/BP;Lymecycline Impurity 3(Lymecycline EP Impurity C)
CBNumber:
CB7438626
Molecular Formula:
C22H23ClN2O7
Molecular Weight:
462.88
MOL File:
13803-65-1.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

ANHYDROTETRACYCLINE HYDROCHLORIDE Properties

Melting point 223 °C
RTECS QI7860000
storage temp. Refrigerator
solubility Soluble in ethanol, DMSO, or DMF
form Powder
color Yellow to bright yellow
Sensitive Moisture Sensitive
BRN 4228856
Stability Hygroscopic
EPA Substance Registry System 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4S,4aS,12aS)- (13803-65-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H319-H361
Precautionary statements  P201-P202-P264b-P280i-P305+P351+P338-P308+P313-P403-P501c
Hazard Codes  Xn
Risk Statements  63-36
Safety Statements  36/37/39-26
WGK Germany  3
HS Code  29413020

ANHYDROTETRACYCLINE HYDROCHLORIDE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR3175 Anhydrotetracycline Hydrochloride pharmaceutical secondary standard, certified reference material 13803-65-1 50MG ₹49253.75 2022-06-14 Buy
Sigma-Aldrich(India) 94664 Anhydrotetracycline hydrochloride certified reference material, TraceCERT? 13803-65-1 10MG ₹23717.58 2022-06-14 Buy
Sigma-Aldrich(India) 37919 Anhydrotetracycline hydrochloride VETRANAL?, analytical standard 13803-65-1 100MG ₹33102.85 2022-06-14 Buy
Product number Packaging Price Buy
PHR3175 50MG ₹49253.75 Buy
94664 10MG ₹23717.58 Buy
37919 100MG ₹33102.85 Buy

ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to bind tetO and block transcription. Anhydrotetracycline (hydrochloride) is a powerful effector in both the tetracycline repressor (TetR) and reverse TetR (revTetR) systems, binding the Tet repressor 35-fold more strongly than Tet. Moreover, anhydrotetracycline poorly binds the 30S ribosomal subunit, compared to Tet, so it does not act as a general inhibitor of translation and is a poor antibiotic. Perhaps related to this, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than a 1,000-fold above the dose that alters transcription through TetR.

Chemical Properties

yellow to bright yellow powder

Uses

Anhydrotetracycline hydrochloride is a salt of a degradation product of tetracycline, formed by dehydration at the C6 position under acidic conditions to aromatise the B ring. Anhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, anhydrotetracycline is considered biologically active and is thought responsible for aspects of tetracycline toxicity.

ANHYDROTETRACYCLINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 109)Suppliers
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Varanous Labs Pvt Ltd +91-7036248882 +91-7036248882 Hyderabad, India 1541 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
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Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
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BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12382 58 Inquiry
VladaChem GmbH +49-7246-3082843 Germany 1860 58 Inquiry
ANHYDROTETRACYCLINE HYDROCHLORIDE AnhydrotetracyclineHCl Anhydrotetracycline hydrochloride, 'can be used as a secondary standard' 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, monohydrochloride, (4S,4aS,12aS)- 5A,6-ANHYDROTETRACYCLINEHYDROCHLORIDE Anhydrotetracycline hydrochloride,'can be used as secondary standard.' Anhydrotetracycline hydrochloride ,97% (4S,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE MONOHYDROCHLORIDE Lymecycline Impurity 3(Lymecycline EP Impurity C) (4S,4aS,12aS)-4-(DiMethylaMino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-Methyl-1,12-dioxo-2-naphthacenecarboxaMide Hydrochloride Anhydrotetracycline hydrochloride CRS Tetracycline Anhydro HCl Aureomycin EP impurity J ANHYDROTETRACYCLINE HYDROCHLORIDE USP/EP/BP Anhydrotetracycline HydrochlorideQ: What is Anhydrotetracycline Hydrochloride Q: What is the CAS Number of Anhydrotetracycline Hydrochloride Q: What is the storage condition of Anhydrotetracycline Hydrochloride Q: What are the applications of Anhydrotetracycline Hydrochloride Anhydrotetracycline Hydrochloride ((4S ,4aS ,12aS )-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-me (1035708) Tetracycline Hydrochloride Impurity C as Hydrochloride (4S,4aS,12aS)-4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide (anhydrotetracycline) Chlortetracycline Hydrochloride Impurity J as Hydrochloride Chlortetracycline Hydrochloride EP Impurity J as Hydrochloride Tetracycline Hydrochloride EP Impurity C as Hydrochloride 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-,hydrochloride (1:1), (4S,4aS,12aS)- Anhydrotetracycline HCl, EvoPure 13803-65-1 Drug Analogues Intermediates & Fine Chemicals Pharmaceuticals