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DIHYDROERGOTAMINE

CAS No.: 511-12-6

Chemical Name:: DIHYDROERGOTAMINE

Synonyms: Levadex;DIHYDROERGOTAMINE;Dihydro Ergotamine D5;9,10-Dihydroergotamine;DIHYDROERGOTAMINE USP/EP/BP;Dihydro Ergotamine Impurity 4;Dihydroergotamine (base and/or unspecified salts);9,10α-Dihydro-12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione;Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-;(6aR,9R,10aR)-N-[(2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline- 9-carboxamide (dihydroergotamine),

CBNumber:: CB7482038

Molecular Formula:: C33H37N5O5

Molecular Weight:: 583.69

MOL File:: 511-12-6.mol

Modify Date:: 2023/5/4 15:12:41

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DIHYDROERGOTAMINE Properties

Melting point	239°
alpha	D20 -64°; 20546 -79° (c = 0.5 in pyridine)
Boiling point	641.14°C (rough estimate)
Density	1.1992 (rough estimate)
refractive index	1.7500 (estimate)
pka	9≅+-.0.60(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P330-P501

DIHYDROERGOTAMINE Chemical Properties,Uses,Production

Uses

Levadex is an intermediate in the synthesis of 2’-Epidihydroergotamine (E584910), which is an ergot alkaloid that exhibits potential neuroprotective properties against degenerative diseases.

Definition

ChEBI: Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the tr atment of migraine and orthostatic hypotension.

brand name

D.H.E. 45 (Valeant); Migranal (Valeant) .

DIHYDROERGOTAMINE Preparation Products And Raw materials

Raw materials

ergotamine

Preparation Products

511-12-6(DIHYDROERGOTAMINE)Related Search:

Sumatriptan ergotamine DIHYDROERGOTAMINE TARTRATE CRYSTALLINE DIHYDROERGOTAMINE BASE DIHYDROERGOTAMINE METHANESULFONATE,Dihydroergotamine monomethanesulfonate,DIHYDROERGOTAMINE MESYLATE,DIHYDROERGOTAMINE METHANESULFONATE SALT

Dihydroergotamine Tartrate Bp,Eur,Ph Dihydroergotamine Mesylate USP,BP,JP,Eur,Ph DIHYDROERGOTAMINE TARTRATE,DIHYDROERGOTAMINE TARTRATE SALT Dihydroergotamine for peak identification DIHYDROERGOTAMINE METHANESULFONATE SALT,DIHYDROERGOTAMINE MESYLATE,DIHYDROERGOTAMINE METHANESULFONATE

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DIHYDROERGOTAMINE Dihydroergotamine (base and/or unspecified salts) 9,10-Dihydroergotamine 9,10α-Dihydro-12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione Levadex DIHYDROERGOTAMINE USP/EP/BP Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)- Dihydro Ergotamine D5 (6aR,9R,10aR)-N-[(2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline- 9-carboxamide (dihydroergotamine), Dihydro Ergotamine Impurity 4 511-12-6