(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)(6-METHOXY-2-(4-METHOXYPHENYL)BENZO[B]THIOPHEN-3-YL)METHANONE

(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)(6-METHOXY-2-(4-METHOXYPHENYL)BENZO[B]THIOPHEN-3-YL)METHANONE Structure
CAS No.
84541-38-8
Chemical Name:
(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)(6-METHOXY-2-(4-METHOXYPHENYL)BENZO[B]THIOPHEN-3-YL)METHANONE
Synonyms
Raloxifene Impurity 2;Sulfamic Acid Impurity 7;Raloxifene IMpurity: IMpurity C;Raloxifene Dimethoxy Impurity/ Raloxifene Bismethyl Ether;Methanone, [6-methoxy-2-(4-methoxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-;[6-methoxy-2-(4-methoxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;(6-Methoxy-2-(4-Methoxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)Methanone
CBNumber:
CB7485271
Molecular Formula:
C30H31NO4S
Molecular Weight:
501.64
MOL File:
84541-38-8.mol
Modify Date:
2023/5/15 10:43:54

(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)(6-METHOXY-2-(4-METHOXYPHENYL)BENZO[B]THIOPHEN-3-YL)METHANONE Properties

Melting point 75-85°C
Boiling point 692.2±55.0 °C(Predicted)
Density 1.198±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility soluble in DMF, DMSO, Methanol
form Solid
pka 8.52±0.10(Predicted)
color Yellow

(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)(6-METHOXY-2-(4-METHOXYPHENYL)BENZO[B]THIOPHEN-3-YL)METHANONE Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

An intermediate in the synthesis of Raloxifene, a nonsteroidal estrogen receptor mixed agonist/antagonist.

(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)(6-METHOXY-2-(4-METHOXYPHENYL)BENZO[B]THIOPHEN-3-YL)METHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(6-Methoxy-2-(4-Methoxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)Methanone Raloxifene IMpurity: IMpurity C Raloxifene Impurity 2 [6-methoxy-2-(4-methoxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone Raloxifene Dimethoxy Impurity/ Raloxifene Bismethyl Ether Methanone, [6-methoxy-2-(4-methoxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]- Sulfamic Acid Impurity 7 84541-38-8 Intermediates & Fine Chemicals Pharmaceuticals