SODIUM 4-HYDROXYBUTYRATE
- CAS No.
- 502-85-2
- Chemical Name:
- SODIUM 4-HYDROXYBUTYRATE
- Synonyms
- GHB;SODIUM OXYBATE;SODIUM 4-HYDROXYBUTANOATE;gammaoh;wy-3478;somsanit;NSC-84223;GHB SODIUM SALT;Oxybate (sodium);Levetiracetam-15
- CBNumber:
- CB7491645
- Molecular Formula:
- C4H9NaO3
- Molecular Weight:
- 128.1
- MOL File:
- 502-85-2.mol
- Modify Date:
- 2024/3/19 15:37:51
| Melting point | 145-146°C |
|---|---|
| Flash point | 9℃ |
| storage temp. | Controlled Substance, -20°C Freezer |
| solubility | DMSO (Slightly), Water (Slightly) |
| form | solid |
| Merck | 13,4840 |
| CAS DataBase Reference | 502-85-2(CAS DataBase Reference) |
| EPA Substance Registry System | Butanoic acid, 4-hydroxy-, monosodium salt (502-85-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P260-P280-P301+P310-P311 | |||||||||
| Hazard Codes | F,T | |||||||||
| Risk Statements | 11-23/24/25-39/23/24/25 | |||||||||
| Safety Statements | 22-24/25-45-36/37-16-7 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | ET4750000 | |||||||||
| F | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| Toxicity | Highly sol in aq solns. LD50 in male, female rats (mg/kg): 2,000, 1,650 i.p. (Bruguerolle) | |||||||||
| NFPA 704 |
|
SODIUM 4-HYDROXYBUTYRATE price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G-001 | GHB sodium salt solution 1.0?mg/mL in methanol (as salt), ampule of 1?mL, certified reference material, Cerilliant? | 502-85-2 | 1ML | ₹2231.1 | 2022-06-14 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| G-001 | 1ML | ₹2231.1 | Buy |
SODIUM 4-HYDROXYBUTYRATE Chemical Properties,Uses,Production
Description
Xyrem is distributed by Jazz Pharmaceuticals, Inc. (Palo Alto, CA). It is an oral solution of sodium oxybate prescribed for narcoleptic patients to treat extreme daytime sleepiness and cataplexy. Xyrem is also known as sodium oxybate which is the same as gamma hydroxybutyric acid (GHB), a drug of abuse. GHB is endogenously produced and present in the central nervous system (CNS) in small concentrations. Accidental overdosing has led to many hospitalizations and deaths. Because of the tendency to abuse GHB, it was classified as a schedule I controlled substance. This meant that GHB had a high potential for abuse and no medical purpose. However, in 2002, because of a series of clinical trials that demonstrated that the compound reduces cataplexy attacks, it was approved for use under the trademark Xyrem. Since GHB had previously been used as a ‘date-rape’ drug, Xyrem is considered a schedule III controlled substance and is distributed in accordance with strict FDA regulations. Xyrem may only be ordered through the ‘Xyrem Success Program.’ Illegal use is punishable under federal and state laws.
Chemical Properties
white crystalline powder
Uses
4-Hydroxybutyric acid sodium salt is an agonist to both GHB and GABAB neural receptors, exhibiting neurotransmitter-like effects. It has been used as a general anesthetic in treatment for sleep disorders and clinical depression, but also has been identified as a “date rape drug”.
Environmental Fate
Xyrem is a water-soluble white to off-white powder, which can be disposed by dumping the oral solution down the sanitary sewer system. This is the preferred method of disposal for drugs which have a high potential for abuse and/or accidental overdose.
SODIUM 4-HYDROXYBUTYRATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Centaur Pharmaceuticals Pvt Ltd | +912266499100 | Mumbai, India | 33 | 58 | Inquiry |
| Amuna Pharmaceuticals LLP | +91-7940397667 +91-8700823105 | Gujarat, India | 14 | 58 | Inquiry |
| ALKEM LABORATORIES LTD | +91 22 3982 99 99 | New Delhi, India | 27 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Wuhan Haorong Biotechnology Co.,ltd | +86-18565342920; +8618565342920 | China | 292 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25247 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Guangzhou Juntang Technology Co., Ltd | 020-36607679 13502246435 | China | 10951 | 58 | Inquiry |
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