RAC 8-HYDROXY EFAVIRENZ

CAS No.: 205754-33-2

Chemical Name:: RAC 8-HYDROXY EFAVIRENZ

Synonyms: 8-HydroxyEfavirenz;RAC 8-HYDROXY EFAVIRENZ;Efavirenz Impurity 11(8-Hydroxy Efavirenz);(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz

CBNumber:: CB7501021

Molecular Formula:: C14H9ClF3NO3

Molecular Weight:: 331.67

MOL File:: 205754-33-2.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:17

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RAC 8-HYDROXY EFAVIRENZ Properties

Melting point	144-154°C
Boiling point	373.6±42.0 °C(Predicted)
Density	1?+-.0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Acetonitrile: soluble; DMSO: soluble; Methanol: soluble
form	A solid
pka	7.18±0.40(Predicted)
color	White to off-white

RAC 8-HYDROXY EFAVIRENZ Chemical Properties,Uses,Production

Description

8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

Chemical Properties

Off-White Solid

Uses

A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor

RAC 8-HYDROXY EFAVIRENZ Preparation Products And Raw materials

Raw materials

Preparation Products

RAC 8-HYDROXY EFAVIRENZ Suppliers

Global( 32)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Guangzhou PI PI Biotech Inc	020-81716320 +86-13602409664	China	3635	55	Inquiry
DC Chemicals	021-58447131 13564518121	China	9412	58	Inquiry
Nantong Hanfang Biotechnology Co. , Ltd.	18616537568	China	30968	58	Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd	17301488900	China	12582	58	Inquiry
TargetMol Chemicals Inc.	15002134094	China	28091	58	Inquiry
SHANGHAI ZZBIO CO., LTD.	13916577892 19921389125	China	12063	58	Inquiry
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	China	9042	58	Inquiry

Supplier	Advantage
Pharma Affiliates	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Guangzhou PI PI Biotech Inc	55
DC Chemicals	58
Nantong Hanfang Biotechnology Co. , Ltd.	58
Nanjing Shizhou Biology Technology Co.,Ltd	58
TargetMol Chemicals Inc.	58
SHANGHAI ZZBIO CO., LTD.	58
Shanghai SuperLan Chemcial Technique Centre	58

205754-33-2(RAC 8-HYDROXY EFAVIRENZ)Related Search:

SE 563 Efavirenz AMino Alcohol Ethyl CarbaMate rac Methyl Efavirenz Efavirenz Related Compound B (15 mg) ((S,E)-6-Chloro-4-(2-Cyclopropylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) rac 8-Hydroxy Efavirenz

Efavirenz Related Compound C (20 mg) (6-chloro-2-cyclopropyl-4-(trifluoromethyl)quinoline) 6-chloro-4-pent-1-ynyl-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one L 741211 Efavirenz rac 8,14-Dihydroxy Efavirenz

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine(Mixture of 2 Diastereomers) Efavirenz IP Impurity A rac 7-Hydroxy Efavirenz [4-Chloro-2-[(1S)-3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propynyl)phenyl]carbamic Acid Methyl Ester

(S)-5-chloro-a-(Cyclopropylacetenyl)-2-[((4-methoxyphenyl)methyl)amino]-a- (trifluoromethyl) benzenemethanol (E-4) Enantiomer Efavirenz Efavirenz Impurity 13(7-Hydroxy Efavirenz)

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RAC 8-HYDROXY EFAVIRENZ 8-HydroxyEfavirenz 6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one (4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one Efavirenz Impurity 11(8-Hydroxy Efavirenz) 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)- 8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz 2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)- 205754-33-2 Metabolites Non-nucleoside Reverse Transcriptase Pharmaceuticals Intermediates & Fine Chemicals Isotope Labeled Compounds