SNC 80

SNC 80 Structure
CAS No.
156727-74-1
Chemical Name:
SNC 80
Synonyms
SNC 80;NIH 10815;(+)-4-[(Ar)-alpha-((2s,5r)-4-allyl-2,5-dimethyl-1-piperazinyl)-3;4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide;(+)-4-[(AR)-A-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAM;(+)-4-[(aR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide;(+)-4-[(AR)-A-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAMIDE;(+)-4-[(αr)-α-((2s,5r)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-n,n-diethylbenzamide;(+)-4-[(AR)-ALPHA-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAMIDE;(+)-4-[(alphaR)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
CBNumber:
CB7712786
Molecular Formula:
C28H39N3O2
Molecular Weight:
449.63
MOL File:
156727-74-1.mol
Modify Date:
2023/9/4 15:51:00

SNC 80 Properties

Melting point 122-123°C
Boiling point 564.8±50.0 °C(Predicted)
Density 1.040
storage temp. Store at RT
solubility DMSO: soluble
form solid
pka 7.29±0.10(Predicted)
color off-white
Stability Store in Freezer
InChIKey KQWVAUSXZDRQPZ-UMTXDNHDSA-N
SMILES C(N(CC)CC)(=O)C1=CC=C([C@@H](N2C[C@@H](C)N(CC=C)C[C@@H]2C)C2=CC=CC(OC)=C2)C=C1

SAFETY

Risk and Safety Statements

WGK Germany  3

SNC 80 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S2812 SNC80 ≥98% (HPLC), solid 156727-74-1 5MG ₹33817.3 2022-06-14 Buy
Sigma-Aldrich(India) S2812 SNC80 ≥98% (HPLC), solid 156727-74-1 25MG ₹135442.4 2022-06-14 Buy
Sigma-Aldrich(India) 5.08161 SNC80 - CAS 156727-74-1 - Calbiochem 156727-74-1 10MG ₹18740 2022-06-14 Buy
Product number Packaging Price Buy
S2812 5MG ₹33817.3 Buy
S2812 25MG ₹135442.4 Buy
5.08161 10MG ₹18740 Buy

SNC 80 Chemical Properties,Uses,Production

Description

SNC 80 is a selective nonpeptide agonist of the δ-opioid receptor (Ki = 0.18 nM, IC50 = 2.73 nM) that is over 2,000-fold less effective at the μ-opioid receptor. It effectively activates μ/δ receptor heteromers (EC50 = 52.8 nM) but not κ/δ or μ/κ heteromers. SNC 80 has antinociceptive as well as pro-convulsant effects in vivo.

Chemical Properties

Crystalline Solid

Uses

A highly selective and potent non-peptide -agonist, 2000-fold selective over u-receptors

Biological Activity

A highly selective and potent non-peptide δ -opioid agonist, 2000-fold selective over μ -opioid receptors.

SNC 80 Suppliers

Global( 81)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9650 58 Inquiry
InvivoChem 13549236410 China 6747 58 Inquiry
DC Chemicals 021-58447131 13564518121 China 9412 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
Beijing Lebo Biotechnology Co., Ltd. 010-50934026 CHINA 6057 58 Inquiry

SNC 80 Spectrum

(+)-4-[(alphaR)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide 4-[(R)-[(2S,5R)-2,5-Dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethylbenzamide (+)-4-[(Ar)-alpha-((2s,5r)-4-allyl-2,5-dimethyl-1-piperazinyl)-3 NIH 10815 (+)-4-[(AR)-A-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAM (+)-4-[(AR)-A-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAMIDE (+)-4-[(AR)-ALPHA-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAMIDE SNC 80 (+)-4-[(αr)-α-((2s,5r)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-n,n-diethylbenzamide 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide (+)-4-[(aR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide Benzamide, 4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl- 156727-74-1 C28H39N3O2 Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents Opioid receptor and opioid-like receptor