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Cefmenoxime hydrochloride

Cefmenoxime hydrochloride Structure
CAS No.
75738-58-8
Chemical Name:
Cefmenoxime hydrochloride
Synonyms
Tacef;Cemix;Cefmax;Bestron;Bestcall;Abbott 50192;CEFMENOXIME HCL;CefMenoxiMe SodiuM;SCE-1365(free acid);sce1365hydrochloride
CBNumber:
CB7763319
Molecular Formula:
C16H18ClN9O5S3
Molecular Weight:
548.01
MOL File:
75738-58-8.mol
MSDS File:
SDS
Modify Date:
2023/5/30 13:40:39
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Cefmenoxime hydrochloride Properties

Melting point >175°C (dec.)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Slightly)
form Solid
color Off-White to Pale Yellow
InChIKey HZYJYGJIOCXOTH-AJVJENPNNA-N
SMILES C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NN=NN1C)(=O)O.Cl |&1:5,7,r|

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2941906000

Cefmenoxime hydrochloride Chemical Properties,Uses,Production

Description

Cef menoxime hydrochloride is a third generation cephalosporin antibiotic. Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in the 3-position; like several other compounds containing this structural element (moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella, Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is relatively ineffective against Pseudomonas and Bacteroidea.

Uses

A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.

Definition

ChEBI: The hemihydrochloride salt of cefmenoxime.

General Description

Cefmenoxime was synthesized by Takeda Pharmaceutical Co. in 1978. It contains aminothiazole and methoxyimino groups in the 7-acyl position and a methyltetrazole group at the 3 position of the cephem nucleus. Cefmenoxime has a wide activity spectrum against gram-positive and gram-negative bacteria, including anaerobes, except Staphylococcus aureus. Cefmenoxime is a member of the so-called third-generation cephalosporins, a recently introduced class of clinically important antibiotics.

Cefmenoxime hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Cefmenoxime hydrochloride Suppliers

Global( 180)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 12210 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12459 58 Inquiry
SIMAGCHEM CORP +86-13806087780 China 17367 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
Capot Chemical Co.,Ltd. 60
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Neostar United (Changzhou) Industrial Co., Ltd. 58
Hebei Mojin Biotechnology Co., Ltd 58
SIMAGCHEM CORP 58

75738-58-8(Cefmenoxime hydrochloride )Related Search:

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8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1) 7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride 7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride Bestcall Bestron Cemix SCE-1365(free acid) Tacef 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), [6R-[6α,7β(Z)]]- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), (6R,7R)- Abbott 50192 Cefmax )(methoxyimino)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-ox ab50912hemihydrochloride cefmenoximehemihydrochloride hydrochloride(2:1),(6r-(6-alpha,7-beta(z)))-o sce1365hydrochloride CEFMENOXIME HCL CEFMENOXIME HYDROCHLORIDE (6R)-7α-[[(2-Amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid·0.5hydrochloride 2Cefmenoxime·Hydrochloride Cefmenoxime Hydrochloride (350 mg) CefMenoxiMe SodiuM (6R,7R)-7-[[(2Z)-(2-AMino-4-thiazolyl)(MethoxyiMino)acetyl]aMino]-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid HeMihydrochloride CefMenoxiMe HCL Sterile (pure) Hydrochloride (syn-isomer) 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride CEFMENOXIME HEMIHYDROCHLORIDE;SCE-1365 HEMIHYDROCHLORIDE SCE-1365 hemihydrochloride (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride(2:1) Cefmenoxime hydrochloride USP/EP/BP Cefmenoxime HCl (SCE-1365) Cefmenoxime Hydrochloride (1097771) Cefmenoxime HCL Powder USP Standard 75738-58-8 75739-58-8 2C16H17N9O5S3HClC32H35ClN18O10S6 C16H17N9O5S32HCl C16H17N9O5S312ClH C16H17N9O5S312HCl 2C16H17N9O5S3HCl C32H35ClN18O10S6 CEFMAX Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds