SQUALESTATIN
- CAS No.
- 144541-82-2
- Chemical Name:
- SQUALESTATIN
- Synonyms
- L-694,599;SQUALESTATIN;ZARAGOZIC ACID A SODIUM SALT;Zaragozic acid A trisodium salt
- CBNumber:
- CB7779233
- Molecular Formula:
- C35H47NaO14
- Molecular Weight:
- 714.74
- MOL File:
- Mol file
- MSDS File:
- SDS
SQUALESTATIN Chemical Properties,Uses,Production
Uses
Zaragozic acid A trisodium salt is a potent inhibitor of squalene synthase.
Biochem/physiol Actions
Potent inhibitor, in vivo and in vitro, of mammalian, fungal and Saccharomyces cervisiae squalene synthase. Squalene synthase is the first committed enzyme in sterol synthesis, catalyzing the reductive condensation of farnesyl pyrophosphate to form squalene. As a squalene synthase inhibitor, zaragozic acid produces lower plasma cholesterol levels in primates. Treatment of rats with zaragozic acid A caused an increase in hepatic low density lipoprotein (LDL) receptor mRNA levels.
SQUALESTATIN Preparation Products And Raw materials
Raw materials
Preparation Products
SQUALESTATIN Suppliers
Global( 10)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
Shanghai Universal Biotech Co.,Ltd | 18768175414 | China | 24998 | 58 | Inquiry |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | China | 4428 | 55 | Inquiry |
SIGMA-RBI | 800 736 3690 (Orders) | Switzerland | 6913 | 91 | Inquiry |
Riedel-de Haen AG | 800 558-9160 | United States | 6825 | 87 | Inquiry |
Energy Chemical | 021-58432009 400-005-6266 | China | 44843 | 58 | Inquiry |
Sigma-Aldrich | 021-61415566 800-8193336 | China | 51471 | 80 | Inquiry |
United States Biological | 800.520.3011 or 781.639.5092 | United States | 6256 | 80 | Inquiry |
144541-82-2(SQUALESTATIN)Related Search:
SQUALESTATIN
L-694,599
ZARAGOZIC ACID A SODIUM SALT
Zaragozic acid A trisodium salt
144541-82-2