pipacycline

CAS No.: 1110-80-1

Chemical Name:: pipacycline

Synonyms: Sieromicin;Pipacicline;Mepicycline;pipacycline;Tetrasolvina;(4S)-4β-Dimethylamino-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,6α,10,12,12aβ-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-2-naphthacenecarboxamide;2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-

CBNumber:: CB7928471

Molecular Formula:: C29H38N4O9

Molecular Weight:: 586.638

MOL File:: 1110-80-1.mol

Modify Date:: 2023/5/21 10:59:17

Request For Quotation

pipacycline Properties

alpha	D20 -195° (c = 0.5); D20 -175° (c = 0.5 in methanol)
Boiling point	895.8±65.0 °C(Predicted)
Density	1.55±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
pka	4.50±1.00(Predicted)

SAFETY

Risk and Safety Statements

Toxicity	LD50 i.v. in white mice: 188 mg/kg (Scalvini, Delmonte)

pipacycline Chemical Properties,Uses,Production

Uses

Pipacycline (mepicycline) is a semi-synthetic tetracycline formed by a Mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracycline. The introduction of the piperazine improves bioavailability, but Mannich bases are pro-drugs, converting back to the parent compound. Pipacycline is used commercially as a salt in combination with penicillin V for parenteral use (penimepicycline). The intrinsic in vitro activity and SARs for the amide region of the tetracycline molecule have not investigated extensively. Pipacycline has not been extensively cited in the literature.

Definition

ChEBI: Tetracycline in which a hydrogen attached to the amide nitrogen is substituted by a 4-[(2-hydroxyethyl)piperazin-1-yl]methyl group.

pipacycline Preparation Products And Raw materials

Raw materials

Tetracycline Paraformaldehyde

Preparation Products

pipacycline Suppliers

Global( 15)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Energy Chemical	021-58432009 400-005-6266	China	44843	58	Inquiry
Lynnchem	86-(0)29-85992781 17792393971	China	4587	58	Inquiry
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	China	11289	58	Inquiry
United States Biological	800.520.3011 or 781.639.5092	United States	6256	80	Inquiry
Hubei Xinyang Medical Technology Co., Ltd	15347293736 15347293736	China	8516	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	029-81124267 15229202216	China	10011	58	Inquiry
Shanghai New Union Textra Import & Export Co., Ltd	+861-348-227-9455	China	2752	60	Inquiry
HONEST JOY HOLDINGS LIMITED	+86-755-26404303	United States	6702	54	Inquiry

Supplier	Advantage
Career Henan Chemica Co	58
BOC Sciences	58
Energy Chemical	58
Lynnchem	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
United States Biological	80
Hubei Xinyang Medical Technology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Shanghai New Union Textra Import & Export Co., Ltd	60
HONEST JOY HOLDINGS LIMITED	54

1110-80-1(pipacycline)Related Search:

Minocycline Tetracycline (S)-2-METHYL-1-PHENYL-BUT-3-EN-1-OL (S)-1-PHENYL-BUT-3-EN-1-OL Apicycline

4-Methyl-1-tetralone 1,2,3,4-Tetrahydro-1-naphthol 1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL 3-(2-ISOPROPYLPHENYL)-1-PROPENE 1-ACETYL-1-CYCLOHEXENE

Sancycline pipacycline

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(4S)-4β-Dimethylamino-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,6α,10,12,12aβ-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Mepicycline Pipacicline Sieromicin Tetrasolvina pipacycline 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)- 1110-80-1 C29H38N4O9