ISOXICAM
![ISOXICAM Structure](CAS/GIF/34552-84-6.gif)
- CAS No.
- 34552-84-6
- Chemical Name:
- ISOXICAM
- Synonyms
- Pacyl;W 8495;Maxicam;Vectren;ISOXICAM;Isoxicamo;Isoxicamum;)-,1,1-dioxide;pacyl(antiinflammatory);Inhibitor,Cyclooxygenase,COX,inhibit,Isoxicam
- CBNumber:
- CB8101486
- Molecular Formula:
- C14H13N3O5S
- Molecular Weight:
- 335.34
- MOL File:
- 34552-84-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:17
SAFETY
Risk and Safety Statements
WGK Germany | 2 |
---|---|
RTECS | DL0703000 |
Toxicity | LD50 in rats (mg/kg): >5000 orally (Whitehouse) |
ISOXICAM Chemical Properties,Uses,Production
Description
Isoxicam is a non-steroidal antiinflammatory agent useful in the treatment of various forms of rheumatoid arthritis, osteoarthritis and musculoskeletal disorders. It is about one-tenth as potent as its structural relative sudoxicam; its similar long T1/2 (>30 hrs.) allows once-daily dosing.
Uses
Isoxicam is used for the same indications as piroxicam. Synonyms for isoxicam are floxicam and maxicam.
Definition
ChEBI: A monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Steve s-Johnson syndrome.
World Health Organization (WHO)
Isoxicam, a nonsteroidal anti-inflammatory agent, was introduced in 1983 for the treatment of rheumatic disorders. By 1985 its use had been associated with serious adverse effects, including four deaths from rare skin reactions. This led to its withdrawal in France followed immediately by the voluntary suspension of marketing worldwide by the major manufacturer.
ISOXICAM Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | China | 3136 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
ShangHai Anpel Co, Ltd. | 18501792038; 18501792038 | China | 9614 | 58 | Inquiry |
Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48465 | 58 | Inquiry |
RD International Technology Co., Limited | 18024082417 | China | 9268 | 58 | Inquiry |
Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | China | 10010 | 58 | Inquiry |
Bide Pharmatech Ltd. | 400-1647117 13681763483 | China | 62163 | 58 | Inquiry |
Nantong Hi-Future Biotechnology Co., Ltd | 18051384581 | China | 3058 | 58 | Inquiry |
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