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ISOXICAM

ISOXICAM Structure
CAS No.
34552-84-6
Chemical Name:
ISOXICAM
Synonyms
Pacyl;W 8495;Maxicam;Vectren;ISOXICAM;Isoxicamo;Isoxicamum;)-,1,1-dioxide;pacyl(antiinflammatory);Inhibitor,Cyclooxygenase,COX,inhibit,Isoxicam
CBNumber:
CB8101486
Molecular Formula:
C14H13N3O5S
Molecular Weight:
335.34
MOL File:
34552-84-6.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:17

ISOXICAM Properties

Melting point 265-271℃
Density 1.588
storage temp. -20°C Freezer
solubility Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form Solid
pka 4.50±1.00(Predicted)
color White to Pale Beige

SAFETY

Risk and Safety Statements

WGK Germany  2
RTECS  DL0703000
Toxicity LD50 in rats (mg/kg): >5000 orally (Whitehouse)

ISOXICAM price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) I1762 Isoxicam analytical standard 34552-84-6 1G ₹9623.43 2022-06-14 Buy
Product number Packaging Price Buy
I1762 1G ₹9623.43 Buy

ISOXICAM Chemical Properties,Uses,Production

Description

Isoxicam is a non-steroidal antiinflammatory agent useful in the treatment of various forms of rheumatoid arthritis, osteoarthritis and musculoskeletal disorders. It is about one-tenth as potent as its structural relative sudoxicam; its similar long T1/2 (>30 hrs.) allows once-daily dosing.

Uses

Isoxicam is used for the same indications as piroxicam. Synonyms for isoxicam are floxicam and maxicam.

Definition

ChEBI: A monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Steve s-Johnson syndrome.

World Health Organization (WHO)

Isoxicam, a nonsteroidal anti-inflammatory agent, was introduced in 1983 for the treatment of rheumatic disorders. By 1985 its use had been associated with serious adverse effects, including four deaths from rare skin reactions. This led to its withdrawal in France followed immediately by the voluntary suspension of marketing worldwide by the major manufacturer.

ISOXICAM Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 63)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
ShangHai Anpel Co, Ltd. 18501792038; 18501792038 China 9614 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48465 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9268 58 Inquiry
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 China 10010 58 Inquiry
Bide Pharmatech Ltd. 400-1647117 13681763483 China 62163 58 Inquiry
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 China 3058 58 Inquiry

ISOXICAM Spectrum

)-,1,1-dioxide 2h-1,2-benzothiazine-3-carboxamide,4-hydroxy-2-methyl-n-(5-methyl-3-isoxazolyl pacyl(antiinflammatory) ISOXICAM 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide Pacyl Vectren W 8495 Isoxicamo Isoxicamum Maxicam 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-, 1,1-dioxide 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1, 1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxa mide Inhibitor,Cyclooxygenase,COX,inhibit,Isoxicam 4-Hydroxy-2-methyl-N-(5-methylisoxazol-3-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide 34552-84-6 C14H13N3O5S Analytical Standards Analytical Chromatography Product Catalog Alphabetic OCTOPIROX