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ChemicalBook > Product Catalog >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Flunoxaprofen

Flunoxaprofen

Flunoxaprofen Structure
CAS No.
66934-18-7
Chemical Name:
Flunoxaprofen
Synonyms
Priaxim;Flunoxaprofen;S-(+)-Flunoxaprofen;Flunoxaprofen USP/EP/BP;(S)-2-(4-Fluorophenyl)-α-methyl-5-benzoxazoleacetic acid;5-Benzoxazoleacetic acid, 2-(4-fluorophenyl)-α-methyl-, (αS)-
CBNumber:
CB81178784
Molecular Formula:
C16H12FNO3
Molecular Weight:
285.273
MOL File:
66934-18-7.mol
MSDS File:
SDS
Modify Date:
2023/7/14 17:40:53
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Flunoxaprofen Properties

Melting point 162-164°
alpha D20 +50° (c = 2% in DMF)
Boiling point 419.4±30.0 °C(Predicted)
Density 1.334±0.06 g/cm3(Predicted)
pka 4.36±0.30(Predicted)

SAFETY

Risk and Safety Statements

Toxicity LD50 orally in mice: ~1200 mg/kg (Dunwell)

Flunoxaprofen Chemical Properties,Uses,Production

Description

Flunoxaprofen is an antiinflammatory related to now withdrawn benoxaprofen, reportedly useful in the treatment of rheumatoid arthritis, myositis, synovitis and osteoarthritis. Its major mechanism of action is reported to be lipoxygenase inhibition, thus enabling the control of inflammation with less severe gastric disturbances.

Definition

ChEBI: A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group (the S-enantiomer). Although it was shown to be effective in treatment of rheumatoid arthritis and osteoarthritis, the clinical use of flunoxaprofen was discontinued due to possible hepatotoxic side-effects.

Flunoxaprofen Preparation Products And Raw materials

Raw materials

Preparation Products

Flunoxaprofen Suppliers

Global( 2)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24639 58 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Supplier Advantage
Dideu Industries Group Limited 58
Lanospharma Laboratories Co.,Ltd 56

66934-18-7(Flunoxaprofen)Related Search:

2-(4-FLUOROPHENYL)BENZOXAZOLE Flunoxaprofen 2-(4-Fluorophenyl)oxazole 2-(4-Fluorophenyl)-α-methyl-5-benzoxazoleacetic acid
Flunoxaprofen (S)-2-(4-Fluorophenyl)-α-methyl-5-benzoxazoleacetic acid Priaxim S-(+)-Flunoxaprofen Flunoxaprofen USP/EP/BP 5-Benzoxazoleacetic acid, 2-(4-fluorophenyl)-α-methyl-, (αS)- 66934-18-7