Chinese english Japanese Germany Korea

Zolenzepine

Zolenzepine Structure
CAS No.
78208-13-6
Chemical Name:
Zolenzepine
Synonyms
Zolenzepine;4,9-Dihydro-1,3-dimethyl-4-[(4-methyl-1-piperazinyl)acetyl]pyrazolo[4,3-b][1,5]benzodiazepin-10(1H)-one;Pyrazolo[4,3-b][1,5]benzodiazepin-10(1H)-one, 4,9-dihydro-1,3-dimethyl-4-[2-(4-methyl-1-piperazinyl)acetyl]-
CBNumber:
CB81180105
Molecular Formula:
C19H24N6O2
Molecular Weight:
368.43
MOL File:
78208-13-6.mol
Modify Date:
2022/12/21 16:56:50
Request For Quotation

Zolenzepine Chemical Properties,Uses,Production

Originator

Zolenzepine,ZYF Pharm Chemical

Manufacturing Process

3.5 g of 4-chloroacetyl-1,3-dimethyl-1,4,9,10-tetrahydropyrazolo[4,3- b][1,5]benzodiazepin-10-one, 8.1 g of N-methylpiperazine and 50 ml of toluene are stirred at 80°C for 2 h. 60 ml of dilute sodium bicarbonate solution are added to the mixture, the layers are separated and the aqueous phase is extracted by shaking it with toluene several times more before concentrating it to dryness in vacuum. The residue is stirred with 100 ml of isopropanol and is filtered; the filtrate is concentrated in vacuum. The residue (4.0 g) is purified by stirring it with diethyl ether and by recrystallizing it from toluene, which yields 2.2 g of 1,3-dimethyl-4-[(4-methylpiperazin-1-yl)acetyl]-1,4,9,10-tetrahydropyrazolo[4,3-b][1,5]benzodiazepin-10-one, melting point 186-188°C.

Therapeutic Function

Antiulcer

Zolenzepine Preparation Products And Raw materials

Raw materials

Sodium bicarbonate 1-Methylpiperazine

Preparation Products

Zolenzepine Suppliers

Global( 1)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Supplier Advantage
Lanospharma Laboratories Co.,Ltd 56

78208-13-6(Zolenzepine)Related Search:

4-AMINO-N,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXAMIDE 5-METHYL-1H-PYRAZOLE-3-CARBOXAMIDE METHYL-(2H-PYRAZOL-3-YLMETHYL)-AMINE N-Methyl-(1-methyl-1H-pyrazol-5-yl)methylamine N-(2-aminophenyl)-2-(4-methylpiperazin-1-yl)acetamide
N1-(2-AMINOPHENYL)-N2,N2-DIMETHYLGLYCINAMIDE N-[(1,3-DIMETHYL-1H-PYRAZOL-5-YL)METHYL]-N-METHYLAMINE 1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXAMIDE (1,3-DIMETHYL-1H-PYRAZOL-5-YL)METHYLAMINE N-(2-aminophenyl)-2-(diethylamino)acetamide
1H-Pyrazole-3-carboxamide,4-amino-(9CI) Zolenzepine
chevron_left

1of3

chevron_right
Zolenzepine 4,9-Dihydro-1,3-dimethyl-4-[(4-methyl-1-piperazinyl)acetyl]pyrazolo[4,3-b][1,5]benzodiazepin-10(1H)-one Pyrazolo[4,3-b][1,5]benzodiazepin-10(1H)-one, 4,9-dihydro-1,3-dimethyl-4-[2-(4-methyl-1-piperazinyl)acetyl]- 78208-13-6