herbimycin C

herbimycin C Structure
CAS No.
91700-92-4
Chemical Name:
herbimycin C
Synonyms
TAN-420D;herbimycin C;Antibiotic TAN-420D;(15R)-17-Demethoxy-15-methoxygeldanamycin;(15R)-17-Demethoxy-15β-methoxygeldanamycin;Geldanamycin, 17-demethoxy-15-methoxy-, (15R)-
CBNumber:
CB81315864
Molecular Formula:
C29H40N2O9
Molecular Weight:
560.64
MOL File:
91700-92-4.mol
MSDS File:
SDS
Modify Date:
2023/7/12 16:53:19

herbimycin C Properties

Boiling point 774.1±60.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Yellow solid.
pka 8.56±0.70(Predicted)

herbimycin C Chemical Properties,Uses,Production

Uses

Herbimycin C is a minor analogue of the herbimycin complex isolated from Streptomyces hygroscopicus. Herbimycin C possesses potent antitumour activity and converts Rous sarcoma virus-infected rat kidney cells into normal cells. Until now limited access has restricted a full investigation of the properties of herbimycin C. Research on related metabolites, herbimycin A and geldanamycin, has stimulated intensive interest in this class as selective antitumour agents and for prolonging the viability of tissue-cultured cells and organs.

herbimycin C Preparation Products And Raw materials

Raw materials

Preparation Products

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herbimycin C (15R)-17-Demethoxy-15-methoxygeldanamycin (15R)-17-Demethoxy-15β-methoxygeldanamycin Antibiotic TAN-420D TAN-420D Geldanamycin, 17-demethoxy-15-methoxy-, (15R)- 91700-92-4