Succinylcholine
- CAS No.
- 306-40-1
- Chemical Name:
- Succinylcholine
- Synonyms
- Diacetylcholine;SUCCINYLCHOLINE;2,2'-(succinylbis(oxy))bis(N,N,N-triMethylethanaMiniuM);2,2'-[(1,4-Dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethylethanaminium];2,2'-[(1,4-Dioxobutane-1,4-diyl)bis(oxy)]bis[N,N,N-trimethyl-1-ethanaminium]
- CBNumber:
- CB81383210
- Molecular Formula:
- C14H30N2O4
- Molecular Weight:
- 0
- MOL File:
- 306-40-1.mol
- Modify Date:
- 2022/12/21 16:56:50
SAFETY
Risk and Safety Statements
| Toxicity | A synthetic muscle relaxant with a curare-like action. Although the selectivity and superficial nature of the paralysis produced by succinylcholine mirrors that of tubocurarine, the specific action is quite different. Succinylcholine is classified as a depolarizing blocking agent, and it blocks acetylcholine receptors by persistent depolarization rather than by the competitive antagonism seen with true curarimimetics. In addition, succinylcholine is inactivated by cholinesterases, limiting the duration of its action. |
|---|
Succinylcholine Chemical Properties,Uses,Production
Description
Succinylcholine is the only therapeutically used depolarizing neuromuscular blocker. Unlike nondepolarizing substances, succinylchloride is not a competitive antagonist; conversely, it is a more stable agonist than acetylcholine. In this manner, succinylcholine differs from acetylcholine only in duration—it lasts longer, causing a more stable depolarization. Thus the process of repolarization is blocked and the muscles relax. During this period, muscles that cause fine movement (ocular, facial, neck) are the most sensitive and are blocked first, after which muscles of the extremities are blocked, and finally the most stable respiratory muscles. Restoration occurs upon completion of drug action.
Uses
Therapeutic use of succinylcholine consists of preventing involuntary patient movement. It is used for brief operations, intubation of the trachea, and other endoscopic procedures. Synonyms of this drug are listenon, midarine, sucostrin, ditilin, and others.
Definition
ChEBI: A quaternary ammonium ion that is the bis-choline ester of succinic acid.
Succinylcholine Preparation Products And Raw materials
Succinylcholine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Micro Orgo Chem | +91-91-022-24969510 +91-9082984052 | Mumbai, India | 66 | 58 | Inquiry |
| AKASH PHARMA EXPORTS | +91-9388123451 +91-9846039283 | Kerela, India | 470 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | China | 31130 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | 029-61856358 15229202216 | China | 10011 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Jigs Chemical ltd | 58 |
| Micro Orgo Chem | 58 |
| AKASH PHARMA EXPORTS | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |