6-THIO-2'-DEOXYGUANOSINE

6-THIO-2'-DEOXYGUANOSINE Structure
CAS No.
789-61-7
Chemical Name:
6-THIO-2'-DEOXYGUANOSINE
Synonyms
tgdr;6-SH-dG;NSC-71261;6-Thio-dG;nci-c01581;Aids010571;Aids-010571;Thiodeoxyguanosine;6-Thio-dG (β-TGdR);6-SH-deoxyguanosine
CBNumber:
CB8152534
Molecular Formula:
C10H13N5O3S
Molecular Weight:
283.31
MOL File:
789-61-7.mol
Modify Date:
2023/5/18 11:31:13

6-THIO-2'-DEOXYGUANOSINE Properties

Melting point 190-192 °C
Boiling point 709.1±70.0 °C(Predicted)
Density 2.02±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), DMF (Slightly), Methanol (Slightly, Heated), Water (Very Slightly)
form Solid
pka 6.81±0.20(Predicted)
color Yellow to Brown

6-THIO-2'-DEOXYGUANOSINE Chemical Properties,Uses,Production

Uses

Guanosine (G837900) derivative with cancer chemotherapeutic properties. It is involved in the inhibition of human RNase H-mediated RNA cleavage from DNA-RNA duplexes via incorporation into DNA.

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2’-deoxy-6-thio-guanosin 2’-deoxythioguanosine 2-amino-9-(2-deoxy-beta-d-erythro-pentofuranosyl)-9h-purine-6(1h)-thion beta-2’-deoxythioguanosine beta-thioguaninedeoxyriboside nci-c01581 tgdr BETA-THIOGUANIDINEDEOXYRIBOSIDE 2'-Deoxy-6-thioguanosine NSC-71261 Thioguanine deoxyriboside β-Thioguanine deoxyriboside 2-Amino-9-(2-deoxy-.beta.-D-erythropentofuranosyl)-9H-purine-6(1H)-thione 6-Mercaptoguaninedeoxyriboside Aids010571 Aids-010571 Thiodeoxyguanosine 2-AMino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-Mercaptopurine 2-AMino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione 2'-Desoxy-6-thioguanosine 6-Thio-dG 6-THIO-2'-DEOXYGUANOSINE 6-Thio-dG (β-TGdR) Mercaptopurine Impurity 13 Guanosine, 2'-deoxy-6-thio- 6-SH-dG 6-SH-deoxyguanosine Inhibitor,inhibit,DNA/RNA Synthesis,6Thio2'Deoxyguanosine,6 Thio 2' Deoxyguanosine 2'-deoxyribo-6-thioguanosine,tgdr,2'-Deoxy-6-thioguanosine 6-THIO-2'-DEOXYGUANOSINE 2'-Deoxy-6-thioguanosine 2'-deoxyribo-6-thioguanosine,tgdr,2'-Deoxy-6-thioguanosine 789-61-7 C10H13N5O3S Bases & Related Reagents Heterocycles Inhibitors Intermediates & Fine Chemicals Nucleotides Pharmaceuticals