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2'-Deoxyguanosine

2'-Deoxyguanosine Structure
CAS No.
961-07-9
Chemical Name:
2'-Deoxyguanosine
Synonyms
DG;deoxyguanosine;2'-DEOXYGUANOSINE;2-amino-9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one;2'-dG;-O-DMT;NSC 22837;D8415_SIGMA;Guanine, 9-(;Oprea1_013861
CBNumber:
CB3209022
Molecular Formula:
C10H13N5O4
Molecular Weight:
267.24
MOL File:
961-07-9.mol
Modify Date:
2023/8/17 19:32:44

2'-Deoxyguanosine Properties

Melting point 300 °C
Boiling point 410.43°C (rough estimate)
Density 1.3382 (rough estimate)
refractive index -42 ° (C=0.2, 1mol/L NaOH)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility NH4OH 1 M: 50 mg/mL, clear to very faintly turbid, yellow to brown
form powder
pka 9?+-.0.20(Predicted)
color White to Off-white
Water Solubility Slightly soluble in water.
BRN 39814
InChIKey OROIAVZITJBGSM-OJFKHTATSA-N
CAS DataBase Reference 961-07-9(CAS DataBase Reference)
NIST Chemistry Reference Deoxyguanosine(961-07-9)
EPA Substance Registry System Guanosine, 2'-deoxy- (961-07-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P501
Risk Statements  20/21/22
Safety Statements  24/25
WGK Germany  3
RTECS  MF8760000
10-23
TSCA  Yes
HS Code  29349990
NFPA 704
1
2 0

2'-Deoxyguanosine price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) D0052 2'-Deoxyguanosine Hydrate 961-07-9 1G ₹3800 2022-05-26 Buy
TCI Chemicals (India) D0052 2'-Deoxyguanosine Hydrate 961-07-9 5G ₹8000 2022-05-26 Buy
TCI Chemicals (India) D0052 2'-Deoxyguanosine Hydrate 961-07-9 25G ₹23800 2022-05-26 Buy
ottokemi D 3444 2-Deoxyguanosine+ 98% 961-07-9 100mg ₹9945 2022-05-26 Buy
ottokemi D 3444 2-Deoxyguanosine+ 98% 961-07-9 500mg ₹28089 2022-05-26 Buy
Product number Packaging Price Buy
D0052 1G ₹3800 Buy
D0052 5G ₹8000 Buy
D0052 25G ₹23800 Buy
D 3444 100mg ₹9945 Buy
D 3444 500mg ₹28089 Buy

2'-Deoxyguanosine Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.

Uses

2'-Deoxyguanosine (Deoxyguanosine; dG) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Definition

ChEBI: 2'-deoxyguanosine is a purine 2'-deoxyribonucleoside having guanine as the nucleobase. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2'-deoxy-D-ribonucleoside and a purine 2'-deoxyribonucleoside. It is functionally related to a guanosine.

Purification Methods

2'-Deoxyguanosine recrystallises from H2O as the monohydrate. [Brown &C5440 Lythgoe J Chem Soc 1990 1950, L

2'-Deoxyguanosine Preparation Products And Raw materials

Global( 457)Suppliers
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CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
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Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Sisco Resech Laboratories Private Limited +91-22-4268 5800 Mumbai, India 655 58 Inquiry

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