2'-Deoxyguanosine
- CAS No.
- 961-07-9
- Chemical Name:
- 2'-Deoxyguanosine
- Synonyms
- DG;deoxyguanosine;2'-DEOXYGUANOSINE;2-amino-9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one;2'-dG;-O-DMT;NSC 22837;D8415_SIGMA;Guanine, 9-(;Oprea1_013861
- CBNumber:
- CB3209022
- Molecular Formula:
- C10H13N5O4
- Molecular Weight:
- 267.24
- MOL File:
- 961-07-9.mol
- Modify Date:
- 2023/8/17 19:32:44
Melting point | 300 °C |
---|---|
Boiling point | 410.43°C (rough estimate) |
Density | 1.3382 (rough estimate) |
refractive index | -42 ° (C=0.2, 1mol/L NaOH) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | NH4OH 1 M: 50 mg/mL, clear to very faintly turbid, yellow to brown |
form | powder |
pka | 9?+-.0.20(Predicted) |
color | White to Off-white |
Water Solubility | Slightly soluble in water. |
BRN | 39814 |
InChIKey | OROIAVZITJBGSM-OJFKHTATSA-N |
CAS DataBase Reference | 961-07-9(CAS DataBase Reference) |
NIST Chemistry Reference | Deoxyguanosine(961-07-9) |
EPA Substance Registry System | Guanosine, 2'-deoxy- (961-07-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332 | |||||||||
Precautionary statements | P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P501 | |||||||||
Risk Statements | 20/21/22 | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | MF8760000 | |||||||||
F | 10-23 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
|
2'-Deoxyguanosine price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemicals (India) | D0052 | 2'-Deoxyguanosine Hydrate | 961-07-9 | 1G | ₹3800 | 2022-05-26 | Buy |
TCI Chemicals (India) | D0052 | 2'-Deoxyguanosine Hydrate | 961-07-9 | 5G | ₹8000 | 2022-05-26 | Buy |
TCI Chemicals (India) | D0052 | 2'-Deoxyguanosine Hydrate | 961-07-9 | 25G | ₹23800 | 2022-05-26 | Buy |
ottokemi | D 3444 | 2-Deoxyguanosine+ 98% | 961-07-9 | 100mg | ₹9945 | 2022-05-26 | Buy |
ottokemi | D 3444 | 2-Deoxyguanosine+ 98% | 961-07-9 | 500mg | ₹28089 | 2022-05-26 | Buy |
2'-Deoxyguanosine Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.
Uses
2'-Deoxyguanosine (Deoxyguanosine; dG) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
Definition
ChEBI: 2'-deoxyguanosine is a purine 2'-deoxyribonucleoside having guanine as the nucleobase. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2'-deoxy-D-ribonucleoside and a purine 2'-deoxyribonucleoside. It is functionally related to a guanosine.
Purification Methods
2'-Deoxyguanosine recrystallises from H2O as the monohydrate. [Brown &C5440 Lythgoe J Chem Soc 1990 1950, L
2'-Deoxyguanosine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Brisben Chemicals | 08048963750 | Mumbai, India | 509 | 58 | Inquiry |
Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Sisco Resech Laboratories Private Limited | +91-22-4268 5800 | Mumbai, India | 655 | 58 | Inquiry |
Supplier | Advantage |
---|---|
CHEMSWORTH | 30 |
CLEARSYNTH LABS LTD. | 58 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Otto Chemie Pvt. Ltd. | 58 |
SynZeal Research Pvt Ltd | 58 |
Brisben Chemicals | 58 |
Anand Agencies | 58 |
Sisco Research Laboratories Pvt. Ltd. | 58 |
Sisco Resech Laboratories Private Limited | 58 |
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