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OCHRATOXIN B

OCHRATOXIN B Structure
CAS No.
4825-86-9
Chemical Name:
OCHRATOXIN B
Synonyms
OCHRATOXIN B;(r)-carbonyl);Ochratoxin B(OTB);ochratoxin b solution;Ochratoxin B 10ug/ml in ACN;ochratoxin B from aspergillus ochraceus;Ochratoxin B, 99%, from Aspergillus ochraceus;Ochratoxin B Solution (10μg/ml in Acetonitrile Solution);ochratoxin b from aspergillus ochraceus (aspergillus oryzae);N-[(8-Hydroxy-3-Methyl-1-oxo-7-isochroManyl)carbonyl]-3-phenyl-L- alanine
CBNumber:
CB2297543
Molecular Formula:
C20H19NO6
Molecular Weight:
369.37
MOL File:
4825-86-9.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:03

OCHRATOXIN B Properties

Melting point 221° (van der Merwe)
alpha D -35° (c = 0.15 in ethanol)
Boiling point 632.4±55.0 °C(Predicted)
Density 1.361±0.06 g/cm3(Predicted)
Flash point -11 °C
storage temp. 2-8°C
solubility DMF: 10 mg/ml; DMSO: 15 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.50 mg/ml
form A crystalline solid
pka 3.40±0.10(Predicted)
color White to off-white
EPA Substance Registry System L-Phenylalanine, N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]- (4825-86-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302-H312-H319-H332
Precautionary statements  P210-P280-P305+P351+P338
Hazard Codes  Xn,T,F
Risk Statements  22-36/37/38-65-48/23/24/25-36/38-11-46-45-36-20/21/22
Safety Statements  26-36-45-16-53-36/37-62
RIDADR  UN 3462 6.1/PG 3
WGK Germany  3
RTECS  AY6825000
HazardClass  6.1(a)
PackingGroup  I
HS Code  39229000
NFPA 704
0
2 0

OCHRATOXIN B price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 32411 Ochratoxin B solution ~10?μg/mL in acetonitrile, analytical standard 4825-86-9 1ML ₹57017.1 2022-06-14 Buy
Product number Packaging Price Buy
32411 1ML ₹57017.1 Buy

OCHRATOXIN B Chemical Properties,Uses,Production

Description

Ochratoxins are mycotoxins produced by Aspergillus and Penicillium species of fungi that contaminate foods. Ochratoxin A (OTA, ) is a chlorinated form with toxicity that targets the kidneys, causing nephropathy and renal adenomas. OTB is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion. OTB inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 μg/ml but lacks the genotoxic activity of OTA, even at higher concentrations.

Uses

Ochratoxin B is the non-chlorinated analogue of the much more extensively studied ochratoxin A. It is co-produced by the same species of Aspergillus and Penicillium that are associated with food spoilage. Ochratoxin B has received little focused investigation and its mode of action and potential hazards have been inferred from ochratoxin A.

General Description

Crystals that exhibit blue fluorescence.

Reactivity Profile

OCHRATOXIN B is incompatible with strong oxidizing agents, strong acids and strong bases. OCHRATOXIN B is a carboxylic acid derivative. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt.

Fire Hazard

Flash point data for OCHRATOXIN B are not available. OCHRATOXIN B is probably combustible.

OCHRATOXIN B Preparation Products And Raw materials

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2-[((3R)-8-HYDROXY-3-METHYL-1-OXOISOCHROMAN-7-YL)CARBONYLAMINO](2S)-3-PHENYLPR OPANOIC ACID OCHRATOXIN B (r)-carbonyl) l-phenylalanine,n-((3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1h-2-benzopyran-7-yl) N-[(8-Hydroxy-3-Methyl-1-oxo-7-isochroManyl)carbonyl]-3-phenyl-L- alanine N-[[(3R)-3,4-Dihydro-8-hydroxy-3-Methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine ochratoxin B from aspergillus ochraceus ochratoxin b from aspergillus ochraceus (aspergillus oryzae) ochratoxin b solution (-)-N-[[(R)-3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine N-[[(3R)-1-Oxo-3-methyl-8-hydroxy-3,4-dihydro-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine N-[[(R)-1-Oxo-3α-methyl-8-hydroxyisochroman-7-yl]carbonyl]-L-phenylalanine (2S)-2-[[(3R)-8-hydroxy-1-keto-3-methyl-isochromane-7-carbonyl]amino]-3-phenyl-propionic acid (2S)-2-[[(3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid (2S)-2-[[(3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-7-carbonyl]amino]-3-phenylpropanoic acid Ochratoxin B(OTB) Ochratoxin B, 99%, from Aspergillus ochraceus Ochratoxin B Solution (10μg/ml in Acetonitrile Solution) L-Phenylalanine, N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]- Ochratoxin B 10ug/ml in ACN (2S)-2-[[(3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-7-carbonyl]amino]-3-phenylpropanoicaci 4825-86-9 Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Cell Signaling and Neuroscience Mold Toxins and Venoms Biotoxins Mycotoxins Single component solutions