4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE

4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE Structure
CAS No.
135721-98-1
Chemical Name:
4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE
Synonyms
S14506HCl;S 14506 HYDROCHLORIDE;1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride;4-Fluoro-N-(2-(4-(7-Methoxynaphthalen-1-yl)piperazin-1-yl)ethyl)benzaMide hydrochloride;4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE
CBNumber:
CB8161035
Molecular Formula:
C24H27ClFN3O2
Molecular Weight:
443.94
MOL File:
135721-98-1.mol
Modify Date:
2023/5/4 17:34:33

4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE Properties

storage temp. Desiccate at RT

4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

S 14506 is a full, highly potent and selective SR-1A agonist.

Biological Activity

Highly potent selective 5-HT 1A receptor full agonist (pK i values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT 1A , 5-HT 1B , 5-HT 1C , 5-HT 2 and 5-HT 3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo .

4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE Suppliers

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4-FLUORO-N-[2-[4-(7-METHOXY-1-NAPHTHALENYL)-1-PIPERAZINYL]ETHYL]BENZAMIDE HYDROCHLORIDE S 14506 HYDROCHLORIDE S14506HCl 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride 4-Fluoro-N-(2-(4-(7-Methoxynaphthalen-1-yl)piperazin-1-yl)ethyl)benzaMide hydrochloride 135721-98-1 C24H27ClFN3O2 C24H26FN3O2HCl