1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Structure
CAS No.
104113-71-5
Chemical Name:
1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE
Synonyms
NPPI;TIMTEC-BB SBB003161;1-(1-NAPHTHYL)PIPERAZINE;1-(1-NAPHTHYL)PIPERAZINE HCL;1-(1-Naphthalenyl)piperazine;1-(Piperazin-1-yl)naphthalene;1-(1-Naphthyl)piperazine*2HCl;1-(Naphth-1-yl)piperazine diHCl;1-(Naphthalen-1-yl)piperazineHCl;1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE
CBNumber:
CB6244792
Molecular Formula:
C14H17ClN2
Molecular Weight:
248.75
MOL File:
104113-71-5.mol
MSDS File:
SDS
Modify Date:
2023/7/14 17:28:49

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Properties

Melting point 235-237 °C
storage temp. Store at -20°C
solubility H2O: soluble
form needles
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
WGK Germany  3
NFPA 704
0
2 0

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ALFA India ALF-J62097-06 1-(1-Naphthyl)piperazine hydrochloride 104113-71-5 5g ₹59625 2022-05-26 Buy
ALFA India ALF-J62097-03 1-(1-Naphthyl)piperazine hydrochloride 104113-71-5 1g ₹20467 2022-05-26 Buy
Product number Packaging Price Buy
ALF-J62097-06 5g ₹59625 Buy
ALF-J62097-03 1g ₹20467 Buy

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

1-(1-Naphthyl)piperazine (1-NP) is a ligand for serotonin (5-hydroxytryptamine, 5-HT) receptors. It acts as an antagonist for 5-HT at 5-HT1 and 5-HT2 in rat cortical membranes with IC50 values of 6 and 1 nM, respectively. 1-NP also blocks contraction in the rat fundus induced by either 5-HT or tryptamine (IC50 = 1 nM for both agonists). 1-NP mimics the 5-HT1 agonist 1-(m-trifluoromethylphenyl)piperazine (TFMPP, ) in decreasing 5-HT receptor turnover and increasing serum corticosterone, suggesting that, in the absence of 5-HT, 1-NP may act as an agonist of the 5-HT1 receptor. However, in squirrel monkeys, 1-NP acts as a non-selective 5-HT receptor antagonist in altering operant behavior. 1-NP also binds to the human 5-HT6 receptor with an affinity comparable to that of 5-HT (Kis = 120 and 100 nM, respectively).

Uses

1-(1-Naphthyl)piperazinemiddotHCl is a mixed agonist/antagonist of the serotonin receptors.

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Suppliers

Global( 41)Suppliers
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A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Nanjing Bicbiotechnology Co., Ltd +86-2552131256 +86-18251840740 China 6000 58 Inquiry
Shaanxi Xihua Chemical Industry Co., Ltd 17691182729 15529505138 China 9963 58 Inquiry
Shanghai Yanbang Pharmaceutical Technology Co., Ltd 15618536883 China 459 58 Inquiry
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 China 39953 58 Inquiry
1-(1-NAPHTHYL)PIPERAZINE 1-(1-NAPHTHYL)PIPERAZINE HCL 1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE 1-(1-Naphthalenyl)piperazine 1-(Piperazin-1-yl)naphthalene 1-(Naphthalen-1-yl)piperazineHCl 1-(1-Naphthyl)piperazine*2HCl Piperazine, 1-(1-naphthalenyl)-, hydrochloride (1:1) TIMTEC-BB SBB003161 NPPI 1-NAPHTHALEN-1-YL-PIPERAZINE HYDROCHLORIDE 1-(Naphth-1-yl)piperazine diHCl Piperazine, 1-(1-naphthalenyl)-, monohydrochloride 1 (1 Naphthyl) piperazine hydrochloride,1(1Naphthyl) piperazine hydrochloride 104113-71-5