Name: 1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE
Brand: chemicalbook
SKU: 104113-71-5

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1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE

₹20467 - ₹59625
Product name: 1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE
CAS: 104113-71-5
MF: C14H17ClN2
MW: 248.75
EINECS:
MDL Number:MFCD00055161
Synonyms:1-(1-NAPHTHYL)PIPERAZINE;1-(1-NAPHTHYL)PIPERAZINE HCL;1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE;1-(1-Naphthalenyl)piperazine;1-(Piperazin-1-yl)naphthalene;1-(Naphthalen-1-yl)piperazineHCl;1-(1-Naphthyl)piperazine*2HCl;Piperazine, 1-(1-naphthalenyl)-, hydrochloride (1:1)

Price2 Properties Safety Information Description

2 prices

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Brand

ALFA India

Package

ManufacturerALFA India
Product numberALF-J62097-06
Product description1-(1-Naphthyl)piperazine hydrochloride
Packaging5g
Price₹59625
Updated2022-05-26
Buy

ManufacturerALFA India
Product numberALF-J62097-03
Product description1-(1-Naphthyl)piperazine hydrochloride
Packaging1g
Price₹20467
Updated2022-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
ALFA India	ALF-J62097-06	1-(1-Naphthyl)piperazine hydrochloride	5g	₹59625	2022-05-26	Buy
ALFA India	ALF-J62097-03	1-(1-Naphthyl)piperazine hydrochloride	1g	₹20467	2022-05-26	Buy

Properties

Melting point :235-237 °C
storage temp. :Store at -20°C
solubility :H₂O: soluble
form :needles
color :white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405	Store locked up.

Description

1-(1-Naphthyl) piperazine (1-NP) is a ligand for serotonin (5-hydroxytryptamine, 5-HT) receptors. It acts as an antagonist for 5-HT at 5-HT1 and 5-HT2 in rat cortical membranes with IC50 values of 6 and 1 nM, respectively. 1-NP also blocks contraction in the rat fundus induced by either 5-HT or tryptamine (IC50 = 1 nM for both agonists). 1-NP mimics the 5-HT1 agonist 1-(m-trifluoromethylphenyl)piperazine (TFMPP, ) in decreasing 5-HT receptor turnover and increasing serum corticosterone, suggesting that, in the absence of 5-HT, 1-NP may act as an agonist of the 5-HT1 receptor. However, in squirrel monkeys, 1-NP acts as a non-selective 5-HT receptor antagonist in altering operant behavior. 1-NP also binds to the human 5-HT6 receptor with an affinity comparable to that of 5-HT (Kis = 120 and 100 nM, respectively).

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