A[5']P5[5']A SODIUM SALT
![A[5']P5[5']A SODIUM SALT Structure](CAS/GIF/4097-04-5.gif)
- CAS No.
- 4097-04-5
- Chemical Name:
- A[5']P5[5']A SODIUM SALT
- Synonyms
- A(5′)P5(5′)A;A[5']P5[5']A SODIUM SALT;DIADENOSINE PENTAPHOSPHATE SODIUM SALT;Diadenosine pentaphosphate pentasodium;5'-ester with adenosine pentasodium salt;P1,P5-Di(adenosine-5;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATESOD IUM;Diadenosine pentaphosphate pentasodium salt;P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE SODIUM SALT;P1,P5-di(adenosine-5')pentaphosphate pentasodium salt 5H2O
- CBNumber:
- CB8189688
- Molecular Formula:
- C20H24N10Na5O22P5
- Molecular Weight:
- 1026.28
- MOL File:
- 4097-04-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/4/17 18:22:24
A[5']P5[5']A SODIUM SALT price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D4022 | P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder | 4097-04-5 | 2MG | ₹4849.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D4022 | P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder | 4097-04-5 | 10MG | ₹15761.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D4022 | P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder | 4097-04-5 | 25MG | ₹26174.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D4022 | P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt ≥95% (HPLC), powder | 4097-04-5 | 50MG | ₹44923.75 | 2022-06-14 | Buy |
A[5']P5[5']A SODIUM SALT Chemical Properties,Uses,Production
Uses
P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt has been used as:
- an adenylate kinase (AK) inhibitor in: sarcoma osteogenic (Saos-2) cells
- mitochondrial lysates during ATP synthesis
- tetramethylrhodamine methyl ester (TMRM) based membrane potential assay
- chromoplasts
General Description
P1,P5-Di(adenosine-5′) pentaphosphate (Ap5A) is a diadenosine polyphosphate, which has a tail-to-tail dimer structure. Ap5A is synthesized in a twostep process involving the formation of adenosine 5′-tetraphosphate (P4A) from the ATP and trimeta-phosphate (P3). In the second step, P4A is converted to Ap5A. The synthesis of Ap5A requires a pH optimum in the range of 7.5 to 8.5 and is modulated by metal ions.
Biochem/physiol Actions
A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.
A[5']P5[5']A SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
A[5']P5[5']A SODIUM SALT Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Aladdin Scientific | United States | 57505 | 58 | Inquiry | |
Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | China | 25003 | 65 | Inquiry |
Absin Bioscience Inc. | 021-38015121-8802 | CHINA | 6208 | 58 | Inquiry |
Merck KGaA | 21-20338288 | China | 292394 | 58 | Inquiry |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | China | 71829 | 60 | Inquiry |
Enzo Biochem Inc | Enzo Biochem Inc. 13797054060 | China | 177174 | 58 | Inquiry |
Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | China | 233051 | 58 | Inquiry |
SIGMA-RBI | 800 736 3690 (Orders) | Switzerland | 6896 | 91 | Inquiry |
Riedel-de Haen AG | 800 558-9160 | United States | 6773 | 87 | Inquiry |
Codow Chemical Co.,Ltd. | 18620099427 | China | 17687 | 55 | Inquiry |