CLOBENZOREX HYDROCHLORIDE

CLOBENZOREX HYDROCHLORIDE Structure
CAS No.
Chemical Name:
CLOBENZOREX HYDROCHLORIDE
Synonyms
CLOBENZOREX HYDROCHLORIDE
CBNumber:
CB8194075
Molecular Formula:
C16H19Cl2N
Molecular Weight:
296.23
MOL File:
Mol file

CLOBENZOREX HYDROCHLORIDE Chemical Properties,Uses,Production

Originator

Asenlix,Aventis

Manufacturing Process

A solution of 21.0 g (0.15 mol) of 2-chlorobenzaldehyde in 100 ml of ethanol (95%) was added to a solution of 20.5 g (0.152 mol) of D-1-phenyl-2-aminopropane in 100 ml of ethanol (95%). After standing for 15 h at room temperature, the ethanol was driven off, and the oily residue was then distilled to yield 36.2 g (94%) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane, boiling point 142°-146°C/0.1 mm Hg.
To the solution of 36.0 g (0.14 mol) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane in 200 ml of dry methanol were added, in portions, 5.3 g (0.14 mol) of sodium borohydride. The mixture was stirred for 1 h at room
temperature, and refluxed for 1 h water (100 ml) was then added and the methanol was removed in vacuo. After acidifying carefully with dilute hydrochloric acid, the solution was made alkaline by dilute sodium hydroxide, and extracted with ether. 33.0 g (90%) of D-N-(1-phenyl-2-propyl)-2-
chlorobenzylamine, boiling point 132°-134°C/0.1 mm Hg, were obtained by distillation.

Therapeutic Function

Anorexic

CLOBENZOREX HYDROCHLORIDE Preparation Products And Raw materials

CLOBENZOREX HYDROCHLORIDE Suppliers

Global( 2)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry

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