ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Pramipexole Impurity 16

Pramipexole Impurity 16

Pramipexole Impurity 16 Structure
CAS No.
104632-27-1
Chemical Name:
Pramipexole Impurity 16
Synonyms
RPPX;Kns 760704;Snd 919cl2x;Dexpramipexole HCl;Dexpramipexole 2HCl;Pramipexole R-Isomer;PraMipexole IMpurity D;Pramipexole BP Impurity D;Pramipexole impurity D CRS;KNS-760704 dihydrochloride
CBNumber:
CB82449027
Molecular Formula:
C10H18ClN3S
Molecular Weight:
247.79
MOL File:
104632-27-1.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:26

Pramipexole Impurity 16 Properties

storage temp. -20°C
solubility H2O: >15mg/mL
form powder
color white to beige
optical activity [α]/D 60 to 70°, c = 1 in methanol

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HS Code  2934200000
NFPA 704
0
2 0

Pramipexole Impurity 16 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0392 Dexpramipexole dihydrochloride ≥98% (HPLC) 104632-27-1 10MG ₹15403.98 2022-06-14 Buy
Sigma-Aldrich(India) SML0392 Dexpramipexole dihydrochloride ≥98% (HPLC) 104632-27-1 50MG ₹62633.45 2022-06-14 Buy
Sigma-Aldrich(India) PHR1824 Pramipexole Related Compound D Pharmaceutical Secondary Standard; Certified Reference Material 104632-27-1 50MG ₹75764.18 2022-06-14 Buy
Product number Packaging Price Buy
SML0392 10MG ₹15403.98 Buy
SML0392 50MG ₹62633.45 Buy
PHR1824 50MG ₹75764.18 Buy

Pramipexole Impurity 16 Chemical Properties,Uses,Production

Description

Pramipexole (Item No. 11981) is an agonist of dopamine receptors that has applications in Parkinson’s disease and other disorders. Pramipexole is usually available as a mixture of enantiomers, with the majority of the dopamine receptor-dependent activity resulting from the (S) form. (R)-Pramipexole is an enantiomer of pramipexole that is ~100-fold less active than the (S) form as a dopamine receptor agonist. For this reason, it can be used as a negative control for the (S) form in the study of dopamine receptors. Both isoforms are antioxidants that target mitochondria to prevent apoptosis. This cytoprotective effect of (R)-pramipexole, without dopaminergic side effects, suggests utility in amyotrophic lateral sclerosis.

Uses

(R)-Pramipexole Dihydrochloride (Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D) is the opposite enantiomer of Pramipexole (P700755), a dopamine-D2-receptor agonist. Dexpramipexole is a low-molecular-weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pramipexole Related Compound D is a pharmaceutical impurity of pramipexole. Pramipexole is a non-ergot dopamine receptor agonist, widely used in the treatment of Parkinson′s disease.

Pramipexole Impurity 16 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 82)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Varanous Labs Pvt Ltd +91-7036248882 +91-7036248882 Hyderabad, India 1541 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12382 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nanjing Doge Biomedical Technology Co., Ltd +86-25-58227606 +86-15305155328 China 4128 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, (R)- Kns 760704 Snd 919cl2x DexpraMipexole (dihydrochloride) PraMipexole IMpurity D (R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride // (R)-Pramipexole dihydrochloride (R)-4,5,6,7-Tetrahydro-6-(propylamino)-benzothiazole-2-amine dihydrochloride RPPX Pramipexole Dihydrochloride Hydrate Impurity (R)-Pramipexole (hydrochloride) Pramipexole Dihydrochloride Hydrate IMP Pramipexole dihydrochloride impurity IV (R)-PRAMIPEXOLE DIHYDROCHLORIDE; KNS 760704; SND 919CL2X Pramipexole R-Isomer Pramipexole EP Impurity D DiHCl (6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine,dihydrochloride Dexpramipexole dihydrochloride ((R)-Pramipexole Pramipexole impurity D CRS KNS-760704 dihydrochloride (R)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine dihydrochloride Dexpramipexole HCl Pramipexole EP Impurity D ((R)-Pramipexole diHCl) Pramipexole Related Compound D ((R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydro (1553815) Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride Dopamine Receptor,inhibit,Inhibitor,KNS-760704,Dexpramipexole,Dexpramipexole dihydrochloride,(R)-Pramipexole,KNS760704,KNS 760704 Pramipexole Impurity 4 Dihydrochloride(Pramipexole EP Impurity D Dihydrochloride) Glycerol Impurity 41((R)-3-chloropropane-1,2-diol) Dexpramipexole 2HCl Pramipexole BP Impurity D Pramipexole EP Impurity D HCl 104632-27-1 28425