Aripiprazole
![Aripiprazole Structure](CAS/GIF/129722-12-9.gif)
- CAS No.
- 129722-12-9
- Chemical Name:
- Aripiprazole
- Synonyms
- ABILIFY;ARIPIPRAZOLE-D8;Arpiprazole;Aripirazole;OPC 31;ABILITAT;OPC 14597;Abilify-d8;OPC 31-d8-;Abilitat-d8
- CBNumber:
- CB8210870
- Molecular Formula:
- C23H27Cl2N3O2
- Molecular Weight:
- 448.39
- MOL File:
- 129722-12-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
Melting point | 139°C |
---|---|
Boiling point | 646.2±55.0 °C(Predicted) |
Density | 1.263±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: soluble5mg/mL, clear (warmed) |
pka | 14.42±0.20(Predicted) |
form | powder |
color | white to beige |
Merck | 14,785 |
BCS Class | 2 |
Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
InChIKey | CEUORZQYGODEFX-UHFFFAOYSA-N |
CAS DataBase Reference | 129722-12-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() GHS02,GHS06,GHS08 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H225-H301+H311+H331-H370 | |||||||||
Precautionary statements | P210-P233-P280-P301+P310-P303+P361+P353-P304+P340+P311 | |||||||||
Hazard Codes | F,Xn | |||||||||
Risk Statements | 11-20/21/22-36 | |||||||||
Safety Statements | 16-36/37 | |||||||||
RIDADR | UN 1993C 3 / PGIII | |||||||||
WGK Germany | 3 | |||||||||
RTECS | VC8275950 | |||||||||
HS Code | 29349990 | |||||||||
Toxicity | TDLo ivn-dog: 0.03 mg/kg/10M TXAPA9 173,120,2001 | |||||||||
NFPA 704 |
|
Aripiprazole price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0935 | Aripiprazole ≥98% (HPLC) | 129722-12-9 | 10MG | ₹5380.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0935 | Aripiprazole ≥98% (HPLC) | 129722-12-9 | 50MG | ₹14440.55 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1784 | Aripiprazole Pharmaceutical Secondary Standard; Certified Reference Material | 129722-12-9 | 500MG | ₹24312.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A-119 | Aripiprazole solution 1.0?mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1?mL, certified reference material, Cerilliant? | 129722-12-9 | 1ML | ₹16837.8 | 2022-06-14 | Buy |
TCI Chemicals (India) | A2496 | Aripiprazole | 129722-12-9 | 1G | ₹4600 | 2022-05-26 | Buy |
Aripiprazole Chemical Properties,Uses,Production
Chemical Properties
Colourless Flake Crystalline Solid
Uses
A deuterated version of Aripiprazole, a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Please note that users have reported separation of this compound and aripiprazole under normal-phase and reverse-phase
General Description
Aripiprazole (Abilify). The newest, longactingaripiprazole (an arylpiperazine quinolinone derivative),appears to be partial agonist of D2 receptors (i.e., itstimulates certain D2 receptors while blocking others dependingon their locations in the brain and the concentrationof drug). Bioavailability of aripiprazole is around 87%, with peak plasma concentration attained at 3 to 5 hours afterdosing. It is metabolized by dehydrogenation, oxidative hydroxylation, and N-dealkylation, largelymediated by hepatic CYPs 3A4 and 2D6.
The diphenylbutylpiperidine class can be considered amodification of the fluorobutyrophenone class. Because oftheir high lipophilicity, the compounds are inherently longacting. Pimozide has been approved for antipsychotic use,and penfluridol has undergone clinical trials in the UnitedStates. Overall, side effects for the two compounds resemblethose produced by the fluorobutyrophenones.
Hazard
A poison.
Safety Profile
A poison by intravenous route.When heated to decomposition it emits toxic vapors ofNOx and Cl-.
Aripiprazole Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
Cadila Pharmaceuticals Ltd | +91-7069076657 +91-7069076657 | Ahmedabad, India | 54 | 58 | Inquiry |
ANWITA APIS | +919000311012 | Hyderabad, India | 198 | 58 | Inquiry |
Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
NB Healthcare Pvt Ltd | +91 7227055467 | Gujarat, India | 37 | 58 | Inquiry |
J S LABS | +91-7330612784 +91-7330612784 | Tamil Nadu, India | 160 | 58 | Inquiry |
SEUTIC | +91-8309787199 +91-8309787199 | Hyderabad, India | 124 | 58 | Inquiry |
KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
Apotex Pharmachem India Pvt Ltd | +91-8022891034 +91-8022891000 | Karnataka, India | 109 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Jigs Chemical ltd | 58 |
Cadila Pharmaceuticals Ltd | 58 |
ANWITA APIS | 58 |
Anant Pharmaceuticals Pvt Ltd | 58 |
NB Healthcare Pvt Ltd | 58 |
J S LABS | 58 |
SEUTIC | 58 |
KARPSCHEM LABORATORIES | 58 |
Aurobindo Pharma Limited | 58 |
Apotex Pharmachem India Pvt Ltd | 58 |
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