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Aripiprazole

Aripiprazole Structure
CAS No.
129722-12-9
Chemical Name:
Aripiprazole
Synonyms
ABILIFY;ARIPIPRAZOLE-D8;Arpiprazole;Aripirazole;OPC 31;ABILITAT;OPC 14597;Abilify-d8;OPC 31-d8-;Abilitat-d8
CBNumber:
CB8210870
Molecular Formula:
C23H27Cl2N3O2
Molecular Weight:
448.39
MOL File:
129722-12-9.mol
MSDS File:
SDS
Modify Date:
2024/7/25 20:04:51

Aripiprazole Properties

Melting point 139°C
Boiling point 646.2±55.0 °C(Predicted)
Density 1.263±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble5mg/mL, clear (warmed)
pka 14.42±0.20(Predicted)
form powder
color white to beige
Merck 14,785
BCS Class 2
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey CEUORZQYGODEFX-UHFFFAOYSA-N
CAS DataBase Reference 129722-12-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P233-P280-P301+P310-P303+P361+P353-P304+P340+P311
Hazard Codes  F,Xn
Risk Statements  11-20/21/22-36
Safety Statements  16-36/37
RIDADR  UN 1993C 3 / PGIII
WGK Germany  3
RTECS  VC8275950
HS Code  29349990
Toxicity TDLo ivn-dog: 0.03 mg/kg/10M TXAPA9 173,120,2001
NFPA 704
0
2 0

Aripiprazole price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0935 Aripiprazole ≥98% (HPLC) 129722-12-9 10MG ₹5380.03 2022-06-14 Buy
Sigma-Aldrich(India) SML0935 Aripiprazole ≥98% (HPLC) 129722-12-9 50MG ₹14440.55 2022-06-14 Buy
Sigma-Aldrich(India) PHR1784 Aripiprazole Pharmaceutical Secondary Standard; Certified Reference Material 129722-12-9 500MG ₹24312.95 2022-06-14 Buy
Sigma-Aldrich(India) A-119 Aripiprazole solution 1.0?mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1?mL, certified reference material, Cerilliant? 129722-12-9 1ML ₹16837.8 2022-06-14 Buy
TCI Chemicals (India) A2496 Aripiprazole 129722-12-9 1G ₹4600 2022-05-26 Buy
Product number Packaging Price Buy
SML0935 10MG ₹5380.03 Buy
SML0935 50MG ₹14440.55 Buy
PHR1784 500MG ₹24312.95 Buy
A-119 1ML ₹16837.8 Buy
A2496 1G ₹4600 Buy

Aripiprazole Chemical Properties,Uses,Production

Chemical Properties

Colourless Flake Crystalline Solid

Uses

A deuterated version of Aripiprazole, a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Please note that users have reported separation of this compound and aripiprazole under normal-phase and reverse-phase

General Description

Aripiprazole (Abilify). The newest, longactingaripiprazole (an arylpiperazine quinolinone derivative),appears to be partial agonist of D2 receptors (i.e., itstimulates certain D2 receptors while blocking others dependingon their locations in the brain and the concentrationof drug). Bioavailability of aripiprazole is around 87%, with peak plasma concentration attained at 3 to 5 hours afterdosing. It is metabolized by dehydrogenation, oxidative hydroxylation, and N-dealkylation, largelymediated by hepatic CYPs 3A4 and 2D6.
The diphenylbutylpiperidine class can be considered amodification of the fluorobutyrophenone class. Because oftheir high lipophilicity, the compounds are inherently longacting. Pimozide has been approved for antipsychotic use,and penfluridol has undergone clinical trials in the UnitedStates. Overall, side effects for the two compounds resemblethose produced by the fluorobutyrophenones.

Hazard

A poison.

Safety Profile

A poison by intravenous route.When heated to decomposition it emits toxic vapors ofNOx and Cl-.

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Aripiprazole Spectrum

ARIPIPRAZOLE ABILITAT 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydrocarbostyril OPC 14597 OPC 31 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone OPC-14597, OPC-31, 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one Form I of Aripiprazole Aripiprazole solution Aripiprazole (200 mg) Aripiprazole, >=99% Alipiprazole 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril Abilify-d8 Abilitat-d8 OPC 14597-d8 OPC 31-d8- 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydrocarbostyril 2(1H)-Quinolinone, 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro- 7-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one Aripiprozole Aripiprazole (Abilify) Aripiprazole Tablets Aripiprazole (Both tablet and inj grade) 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one Crystal forms reference substance of Aripiprazole Form II of Aripiprazole Form C of Aripiprazole Form B of Aripiprazole Aripiprazole Form I Aripiprazole Form II Aripiprazole Form A Aripiprazole Form B Aripiprazole Form C Aripiprazole Form D Aripiprazole Form E Aripiprazole Form F Aripiprazole Form G Aripiprazole, 98%, a human 5-HT1A receptor partial agonist Aripiprazole Manufacturer Aripiprazole > Aripiprazole CRS Aripiprazole USP/EP/BP Aripiprazole (OPC-14597) AripiprazoleQ: What is Aripiprazole Q: What is the CAS Number of Aripiprazole Q: What is the storage condition of Aripiprazole Q: What are the applications of Aripiprazole TIANFU-CHEM CAS:129722-12-9 Aripiprazole Aripiprazole (1042634) ARIPIPRAZOLE-D8 ABILIFY Arpiprazole Aripirazole Aripiprazole Type 1 Aripirazole (USP) Aripiprazole 7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-3,4- dihydroquinolin-2(1H)-one 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydrChemicalbookocarbostyril 129722-12-9