(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide

(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide Structure
CAS No.
170863-34-0
Chemical Name:
(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide
Synonyms
Isavuconazole Impurity 80;Isavuconazole Impurity 52;(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanethioaMide;[R-(R*,R*)]-β-(2,4-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanethioaMide;(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide;1H-1,2,4-Triazole-1-butanethioamide, β-(2,4-difluorophenyl)-β-hydroxy-α-methyl-, (αR,βR)-;(alphaR,betaR)-beta-(2,4-Difluorophenyl)-beta-hydroxy-alpha-methyl-1H-1,2,4-triazole-1-butanethioamide
CBNumber:
CB82620738
Molecular Formula:
C13H14F2N4OS
Molecular Weight:
312.34
MOL File:
170863-34-0.mol
Modify Date:
2024/7/10 17:45:06

(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide Properties

Boiling point 536.4±60.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform
pka 11.74±0.29(Predicted)
form Foam
color Off-Wihte

(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide Chemical Properties,Uses,Production

Chemical Properties

Off-Wihte Foam

Uses

(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide is used in the preparation of triazole antifungal agents.

(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide (αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanethioaMide [R-(R*,R*)]-β-(2,4-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanethioaMide (alphaR,betaR)-beta-(2,4-Difluorophenyl)-beta-hydroxy-alpha-methyl-1H-1,2,4-triazole-1-butanethioamide 1H-1,2,4-Triazole-1-butanethioamide, β-(2,4-difluorophenyl)-β-hydroxy-α-methyl-, (αR,βR)- Isavuconazole Impurity 52 Isavuconazole Impurity 80 170863-34-0