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1-Chloroethyl chloroformate

1-Chloroethyl chloroformate Structure
CAS No.
50893-53-3
Chemical Name:
1-Chloroethyl chloroformate
Synonyms
ACE-CL;1-Chloroethyl carbonochloridate;α-Chloroethyl Chloroformate;RELU-012;a-Chloroethoxycarbonyl chloride;1-ChL;1-Chlorethylchlorformiat;Isavuconazole Impurity 36;Isavuconazole Impurity 54;1-Chlorothyl chloroformate
CBNumber:
CB5320341
Molecular Formula:
C3H4Cl2O2
Molecular Weight:
142.97
MOL File:
50893-53-3.mol
MSDS File:
SDS
Modify Date:
2024/8/24 19:19:26

1-Chloroethyl chloroformate Properties

Melting point -65°C
Boiling point 118-119 °C (lit.)
Density 1.325 g/mL at 25 °C (lit.)
vapor pressure 3.25 psi ( 20 °C)
refractive index n20/D 1.422(lit.)
Flash point 105 °F
storage temp. 2-8°C
solubility Miscible with most organic solvents.
form Liquid
color Clear colorless
Sensitive Moisture Sensitive
BRN 1747601
Stability Hygroscopic, Moisture Sensitive
InChIKey QOPVNWQGBQYBBP-UHFFFAOYSA-N
CAS DataBase Reference 50893-53-3(CAS DataBase Reference)
NIST Chemistry Reference «ALPHA»-chloroethyl chloroformate(50893-53-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H226-H302-H314
Precautionary statements  P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  T
Risk Statements  10-22-23-34
Safety Statements  26-36/37/39-45
RIDADR  UN 2742 6.1/PG 2
WGK Germany  3
10-19-21
TSCA  No
HazardClass  6.1
PackingGroup  II
HS Code  29159000
NFPA 704
2
4 0
W

1-Chloroethyl chloroformate price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 301485 1-Chloroethyl chloroformate 98% 50893-53-3 5G ₹1558.8 2022-06-14 Buy
Sigma-Aldrich(India) 301485 1-Chloroethyl chloroformate 98% 50893-53-3 25G ₹4330 2022-06-14 Buy
ALFA India ALF-L14197-14 1-Chloroethyl chloroformate, 98% 50893-53-3 25g ₹7216 2022-05-26 Buy
TCI Chemicals (India) C1395 1-Chloroethyl Chloroformate min. 98.0 % 50893-53-3 25G ₹5200 2022-05-26 Buy
ALFA India ALF-L14197-06 1-Chloroethyl chloroformate, 98% 50893-53-3 5g ₹2010 2022-05-26 Buy
Product number Packaging Price Buy
301485 5G ₹1558.8 Buy
301485 25G ₹4330 Buy
ALF-L14197-14 25g ₹7216 Buy
C1395 25G ₹5200 Buy
ALF-L14197-06 5g ₹2010 Buy

1-Chloroethyl chloroformate Chemical Properties,Uses,Production

Chemical Properties

Clear and colorless liquid

Uses

1-Chloroethyl chloroformate was used:

  • for N-demethylation reaction during determination of multiple drugs of abuse in biological fluids using capillary electrophoresis with native fluorescence and laser-induced fluorescence detection
  • as catalyst in chemoselective desilylation of silyl-protected alcohols
  • as reagent in N-demethylation of tertiary amines to produce drug metabolite reference material for forensic toxicological applications
  • as reagent to cleave benzhydryl groups from amines

Preparation

1-Chloroethyl chloroformate is obtained by stirring phosgene and acetaldehyde in the presence of benzyltributylammonium chloride, followed by distillation (96% yield).

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1-Chloroethyl carbonochloridoate 1-CHLOROETHYL CHLOROFORMATE, 97+% 1-Chloroethyl chloroformate,Carbonochloridic acid 1-Chlotoethyl chloroformate 1-Chloromethyl-4-fluoro-1,4-diazabicyclo[2.2.2]octane 1-Chlorocarbonyloxy-1-chloroethane α-Chloroethoxycarbonyl Chloride 1-Chloroethyl chloroforMate,99% 1-Chlorothyl chloroformate 1-Chloroethyl chloridocarbonate Carbonochloridic acid, 1-chloroethyl ester 1-CHLOROETHYL CHLOROFORMATE Ethyl chloroforMate-1- chloride 1 - chlorine ethyl chloride acid ester Chloroformic Acid 1-Chloroethyl Ester ACE-Cl CHLOROFORMIC ACID 1-CHLOROETHYL ESTER 1-Chloroethylchloroformate,98% 1-Chloroethyl chloroformate (JCC) 1-CHLOROETHYL CHLOROFORMATE 99% Chloroethyl 1-chloroformate 1 - chlorine ethyl chloride acid es 1-ChL 1-Chloroethyl Chlorofomate 1-Chlorethylchlorformiat Isavuconazole Impurity 36 1-Chloroethyl Chloroformate > Chloroformic Acid 1-Chloroethyl Ester,>98% ACE-CL 1-Chloroethyl carbonochloridate α-Chloroethyl Chloroformate a-Chloroethoxycarbonyl chloride RELU-012 Isavuconazole Impurity 54 1-Chloroethyl chloroformate (1-CECF) 1-Chloroethyl Chloroformate, ≥ 98.0% 50893-53-3 50593-53-3 50893-53-4 CH3CHClOCOCl Carbonyl Compounds Building Blocks Synthetic Reagents Protecting and Derivatizing Reagents Protection and Derivatization Others Organic Building Blocks Acid Halides Acid Halides Building Blocks Carbonyl Compounds Chemical Synthesis Organic Building Blocks CHLOROFORMATES 50893-53-3