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Chloromethyl chloroformate

Chloromethyl chloroformate Structure
CAS No.
22128-62-7
Chemical Name:
Chloromethyl chloroformate
Synonyms
ChloroMethyl carbonochloridate;JMC;CMCF;Tenofovir Impurity 42;Tenofovir Impurity 65;Tenofovir Impurity 241;Tenofovir Impurity 42 CRS;CHLOROMETHYL CHLOROFORMATE;Chloromethylchloroformate,97%;Chloromethyl chloromethanoate
CBNumber:
CB3271092
Molecular Formula:
C2H2Cl2O2
Molecular Weight:
128.94
MOL File:
22128-62-7.mol
MSDS File:
SDS
Modify Date:
2023/6/8 17:06:39

Chloromethyl chloroformate Properties

Melting point <-20°C
Boiling point 107-108 °C(lit.)
Density 1.449 g/mL at 20 °C
refractive index n20/D 1.428
Flash point 95°C
storage temp. 2-8°C
solubility Chloroform (Soluble), Methanol (Slightly)
form clear liquid
color Colorless to Light yellow to Light orange
Water Solubility Slightly miscible with water.
Sensitive Moisture Sensitive
BRN 506426
Stability Extremely Moisture Sensitive, Hygroscopic
CAS DataBase Reference 22128-62-7(CAS DataBase Reference)
EPA Substance Registry System Carbonochloridic acid, chloromethyl ester (22128-62-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS06
Signal word  Danger
Hazard statements  H314-H331
Precautionary statements  P261-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  T
Risk Statements  23-34
Safety Statements  26-36/37/39-45
RIDADR  UN 2745 6.1/PG 2
WGK Germany  3
10-19-21
HS Code  2915.90.5050
HazardClass  6.1
PackingGroup  II
NFPA 704
1
3 0

Chloromethyl chloroformate price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 23181 Chloromethyl chloroformate ≥98.0% (GC) 22128-62-7 10ML ₹11214.7 2022-06-14 Buy
Sigma-Aldrich 23181 Chloromethyl chloroformate ≥98.0% (GC) 22128-62-7 50ML ₹42845.35 2022-06-14 Buy
Sigma-Aldrich(India) 23181 Chloromethyl chloroformate ≥98.0% (GC) 22128-62-7 50ML ₹42845.35 2022-06-14 Buy
TCI Chemicals (India) C1396 Chloromethyl Chloroformate min. 95.0 % 22128-62-7 25G ₹6200 2022-05-26 Buy
ALFA India ALF-L09527-18 Chloromethyl chloroformate, 97% 22128-62-7 50g ₹15432 2022-05-26 Buy
Product number Packaging Price Buy
23181 10ML ₹11214.7 Buy
23181 50ML ₹42845.35 Buy
23181 50ML ₹42845.35 Buy
C1396 25G ₹6200 Buy
ALF-L09527-18 50g ₹15432 Buy

Chloromethyl chloroformate Chemical Properties,Uses,Production

Chemical Properties

Chloromethyl chloroformate is Clear Colourless Oil

Uses

Chloromethyl chloroformate is used as a reagent in the synthesis of carbamates and carbonates.

General Description

Chloromethyl chloroformate is a colorless liquid with a penetrating, irritating odor. Denser than water. Contact may irritate skin, eyes and mucous membranes. Toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.

Air & Water Reactions

Reacts with moisture in air to generate heat and hydrochloric acid fumes [Merck, 11th ed., 1989]. Reacts with water.

Reactivity Profile

CHLOROMETHYLCHLOROFORMATE is water reactive. Incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars etc.). Substance will react with water (some violently), releasing corrosive and/or toxic gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Chloromethyl chloroformate Preparation Products And Raw materials

CHLOROFORMIC ACID CHLOROMETHYL ESTER CHLOROMETHYL CHLOROFORMATE CMCF CHLOROMETHYL CHLOROFORMATE (JMC)(INTERMEDIATE OF TENOFOVIR DISOPROXIL FUMARATE) Chloromethylchloroformate,97% chlorocarbonicacidchloromethylester Chloromethyl Chloroformate (JMC) Carbonochloridic acid chloromethyl ester Chloromethoxycarbonyl chloride Formic acid, chloro-, chloromethyl ester ChloroMethyl chloroforMate >=98.0% (GC) Chloromethyl Chloroformate > JMC ChloroMethyl carbonochloridate Tenofovir Impurity 42 Tenofovir Impurity 65 Tenofovir Impurity 241 Tenofovir Impurity 42 CRS Chloromethyl chloromethanoate 22128-62-7 ClCO2CH2Cl ClCH2OCOCl ClCOOCH2Cl Organic Building Blocks Building Blocks Carbonyl Compounds Acid Halides Miscellaneous Reagents Acid HalidesDerivatization Reagents HPLC Carbonyl ChloridesDerivatization Reagents HPLC Carbonyl Compounds Fluorescence Halogenated Organic Building Blocks